Research areas

  1. Published

    Conformational changes and ligand recognition of Escherichia coli D-xylose binding protein revealed

    Sooriyaarachchi, S., Ubhayasekera, W., Park, C. & Mowbray, S. L., 1 Oct 2010, In: Journal of Molecular Biology. 402, 4, p. 657-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae

    Mellergaard Larsen, M., Adsersen, A., Davis, A. P., Lledó, M. D., Jäger, A. K. & Rønsted, Nina, Oct 2010, In: Biochemical Systematics and Ecology. 38, 5, p. 1026-1034

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands

    Krogsgaard-Larsen, N., Jensen, Anders A. & Kehler, J., 15 Sep 2010, In: Bioorganic & Medicinal Chemistry Letters. 20, 18, p. 5431-5433

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Direct interaction between CD91 and C1q

    Duus, K., Hansen, E. W., Tacnet, P., Frachet, P., Arlaud, G. J., Thielens, N. M. & Houen, G., 1 Sep 2010, In: FEBS Journal. 277, 17, p. 3526-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    EASL clinical practice guidelines on the management of asites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis

    Pere, G., Angeli, P., Lenz, K., Søren, M., Moore, K., Moreau, R., Merkel, C., Larsen, H. R., Bernardi, M., Garcia-Tsao, G. & Hayes, P., 1 Sep 2010, In: Journal of Hepatology. 53, 3, p. 397-417 30 p.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  6. Published

    Zinc ions bind to and inhibit activated protein C

    Zhu, T., Ubhayasekera, W., Nickolaus, N., Sun, W., Tingsborg, S., Mowbray, S. L. & Schedin-Weiss, S., 1 Sep 2010, In: Thrombosis and Haemostasis. 104, 3, p. 544-553

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures

    Suñol, C., Babot, Z., Cristòfol, R., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, Sep 2010, In: Neurochemical Research. 35, 9, p. 1384-1390 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Application of Q2MM to stereoselective reactions

    Nilsson Lill, S. O., Forbes, A., Donoghue, P., Verdolino, V., Wiest, O., Rydberg, P. & Norrby, P., Sep 2010, In: Current Organic Chemistry. 14, 15, p. 1629-1645

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)

    Saaby, Lasse, Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In: Planta Medica. 76, 12, p. 1171

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Collabortion care models: how pharmacy students vary their communication with diabetes patients and their GPs respectively

    Kaae, Susanne, Sørensen, E. W., Nørgaard, Lotte Stig & Søndergaard, B., Aug 2010, In: Pharmacy Practice News. 8, Suppl. 1, p. 43

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Content of antidepressant hyperforin correlates with translucent glands in Hypericum perforatum L.

    Soelberg, Jens, Johansen, B. B. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1325

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus

    Schou, J., Kristiansen, Uffe, Stafford, G. I., van Heerden, F. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1217

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Phylogeny as selection tool for exploring CNS-activity in the Amaryllidaceae

    Rønsted, Nina, Bay-Smidt, M. G. K., Krydsfeldt, K., van Staden, J., Stafford, G. I. & Jäger, A. K., Aug 2010, In: Planta Medica. 76, 12, p. 1178

    Research output: Contribution to journalConference articleResearchpeer-review

  14. Published

    Phytochemical profile and in vitro activities of Capsella bursa-pastoris L. extracts

    Grosso, C., Vinholes, J., Goncalves, R., Jäger, A., Valentao, P. & Andrade, P., Aug 2010, In: Planta Medica. 76, 12, p. 1239

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    The effect of structural characteristics of Lycopodane-type alkaloids on their acetylcholinesterase inhibitory activity in silico

    Halldorsdottir, E., Jaroszewski, J. W. & Olafsdottir, E., Aug 2010, In: Planta Medica. 76, 12, p. 1212

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    The pharmacophore of thapsigargin

    Christensen, Søren Brøgger, Skytte, D. M., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M. & Møller, J. V., Aug 2010, In: Planta Medica. 76, 12, p. 1187

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Brain activation due to postoperative pain from the right hand measured with regional cerebral blood flow using positron emission tomography

    Gordh, T., Vinnars, B., Blomberg, H., Modig, J., Frederikson, M. & Honoré, P. G. H., Jul 2010, In: Scandinavian Journal of Pain. 1, 3, p. 115-119 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    1H NMR metabolic fingerprinting of saffron extracts

    Yilmaz, A., Nyberg, N. T., Mølgaard, Per, Asili, J. & Jaroszewski, J. W., 17 Jun 2010, In: Metabolomics. 6, 4, p. 511-517

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Ribavirin dosage in patients with HCV genotypes 2 and 3 who completed short therapy with peg-interferon alpha-2b and ribavirin

    Mangia, A., Dalgard, O., Minerva, N., Verbaan, H., Bacca, D., Larsen, H. R., Copetti, M., Caretta, V., Piazzollla, V., Cozzolongo, R., Mottola, L. & Andriulli, A., 1 Jun 2010, In: Alimentary Pharmacology and Therapeutics. 31, 12, p. 1346-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Ionophores in the Environment

    Bak, S. A., Hansen, M., Björklund, E. & Halling-Sørensen, B., 24 May 2010.

    Research output: Contribution to conferencePosterResearch

  21. Published

    In patients with HCV genotype 2 or 3 infection and RVR 14 weeks treatment is noninferior to 24 weeks: pooled analysis of two Scandinavian trials

    Dalgard, O., Bjoro, K., Larsen, H. R. & Verbaan, H., 1 May 2010, In: European Journal of Gastroenterology and Hepatology. 22, 5, p. 552-556 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions

    Ihrmark, K., Asmail, N., Ubhayasekera, W., Melin, P., Stenlid, J. & Karlsson, M., 15 Mar 2010, In: Evolutionary Bioinformatics Online. 6, p. 1-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    SMARTCyp: A 2D method for prediction of cytochrome P450-mediated drug metabolism

    Rydberg, P., Gloriam, David E., Zaretzki, J., Breneman, C. & Olsen, L., 15 Mar 2010, In: ACS Medicinal Chemistry Letters. 1, 3, p. 96-100

    Research output: Contribution to journalLetterResearchpeer-review

  24. Published

    Amino acid derived 1,4-dialkyl substituted imidazolones

    Diness, Frederik & Meldal, Morten Peter, 11 Mar 2010, In: Biopolymers. 94, 2, p. 236-241

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Chemical composition of the essential oils from Iranian conifers. Part I: Aroma profiles of leaves and fruits of Juniperus polycarpos var. polycarpos (Cupressaceae)

    Emami, S. A., Afsharypuor, S., Asili, J. & Sairafianpour, M., Mar 2010, In: Journal of Essential Oil Research. 22, 2, p. 103-106

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Frydenvang, Karla Andrea, Hansen, L., Nielsen, P. G. & Jaroszewski, J. W., 18 Feb 2010, In: Journal of Natural Products. 73, 4, p. 776-779

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors reverses subcronic PCP-induced deficits in the novel object recognition task in rats

    Nielsen, T. D., Larsen, D. B., Hansen, S. L., Grayson, B., Neill, J. C. & Plath, N., 11 Feb 2010, In: Behavioural Brain Research. 207, 1, p. 144-150 7 p.

    Research output: Contribution to journalJournal articleResearch

  28. Published

    Regioselective functionalization of 2-(2'-fluorophenyl)-3-cyanopyridine and its cyclization to benzo[h]-1,6-naphthyridines

    Cailly, T. B. G. & Begtrup, M., 6 Feb 2010, In: Tetrahedron. 66, 6, p. 1299-1307

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Peptoid-Peptide hybrid backbone architectures

    Olsen, Christian Adam, 25 Jan 2010, In: ChemBioChem. 11, 2, p. 152-160

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction

    Bach, Anders & Strømgaard, Kristian, 14 Jan 2010, Patent No. WO2010/004003 (Granted: EP2320927B1; US9241967B2)

    Research output: Patent

  31. Published

    The emerging role of promiscuous 7TM receptors as chemosensors for food intake

    Wellendorph, Petrine, Johansen, L. D. & Bräuner, Hans, 1 Jan 2010, Incretins and insulin secretion. Litwack, G. (ed.). Amsterdam: Elsevier Editora, Vol. 84. p. 151-184 (Vitamins & hormones, Vol. 84).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  32. Published

    "Patients don't lie"; a view on adherence in asthma

    Møldrup, C., Stein, J. & Søndergaard, B., 2010, In: Pharmacy World and Science. 32, 6, p. 795-798

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    5-Hydroxy-L-tryptohan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

    Broberg, M. L., Holm, R., Jensen, K. G., Sveigaard, C., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: European Journal of Pharmaceutical Sciences. 39, 1-3, p. 68-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Hvad er forskning? Normer, videnskab og samfund.

    Emmeche, Claus (ed.) & Faye, Jan (ed.), 2010, Nyt fra Samfundsvidenskaberne. 275 p.

    Research output: Book/ReportBookResearchpeer-review

  35. Published

    Short communication: Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products

    Jäger, A. K., Saaby, Lasse, Kudsk, D. S., Witt, K. C. & Mølgaard, Per, 2010, In: Journal of Dairy Science. 93, 6, p. 2351-2353

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A community standard format for the representation of protein affinity reagents

    Gloriam, D. E. I., Orchard, S., Bertinetti, D., Björling, E., Bongcam-Rudloff, E., Borrebaeck, C. A. K., Bourbeillon, J., Bradbury, A. R. M., de Daruvar, A., Dübel, S., Frank, R., Gibson, T. J., Gold, L., Haslam, N., Herberg, F. W., Hiltke, T., Hoheisel, J. D., Kerrien, S., Koegl, M., Konthur, Z. & 16 others, Korn, B., Landegren, U., Montecchi-Palazzi, L., Palcy, S., Rodriguez, H., Schweinsberg, S., Sievert, V., Stoevesandt, O., Taussig, M. J., Ueffing, M., Uhlén, M., van der Maarel, S., Wingren, C., Woollard, P., Sherman, D. J. & Hermjakob, H., 2010, In: Molecular and Cellular Proteomics. 9, 1, p. 1-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. s1, p. 288-289

    Research output: Contribution to journalConference abstract in journalResearch

  38. Published

    A method for analysis of dimethyl selenide and dimethyl diselenide by LC-ICP-DRC-MS

    Lunøe, K., Skov, S., Gabel-Jensen, C., Stürup, Stefan & Gammelgaard, Bente, 2010, In: Analytical and Bioanalytical Chemistry. 398, 7-8, p. 3081-3086

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity

    Stanley, N. J., Hutchinson, M. R., Kvist, T., Nielsen, Birgitte, Mathiesen, Jesper M., Bräuner, Hans, Avery, T. D., Tiekink, E. R. T., Pedersen, D. S., Irvine, R. J., Abell, A. D. & Taylor, D. K., 2010, In: Bioorganic & Medicinal Chemistry. 18, 16, p. 6089-6098

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A novel hybrid chromatography - crystallization process for the isolation and purification of a natural pharmaceutical ingredient from a medicinal herb

    Qu, H., Christensen, K. B., Fretté, X. C., Tian, F., Qu, H., Rantanen, Jukka & Christensen, L. P., 2010, In: Organic Process Research and Development. 14, 3, p. 585-591

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A pharmacokinetic and pharmacodynamic study of oral oxycodone in a human experimental pain model of hyperalgesia

    Olesen, A. E., Upton, R., Staahl, C., Christrup, Lona Louring, Arendt-Nielsen, L. & Drewes, A. M., 2010, In: Clinical Pharmacokinetics. 49, 12, p. 817-827

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa

    Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, Søren Brøgger, Søhoel, H. & Massanet, G. M., 2010, In: Planta Medica. 76, 3, p. 284-290

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1)

    Omkvist, D. H., Larsen, S. B., Nielsen, C. U., Steffansen, B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 2010, In: The AAPS Journal. 12, 3, p. 385-396

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A synthetic combinatorial strategy for developing a-conotoxin analogs as potent a7 nicotinic acetylcholine receptor antagonists

    Armishaw, C. J., Singh, N., Medina-Franco, J. L., Clark, R. J., Scott, K. C. M., Houghten, R. A. & Jensen, Anders A., 2010, In: Journal of Biological Chemistry. 285, 3, p. 1809-1821

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

    Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

    Research output: Contribution to journalJournal articleResearch

  46. Published

    Absorptive transporters

    Nielsen, C. U., Steffansen, B. & Larsen, Birger Brodin, 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage from evaluation. Steffansen, B., Brodin, B. & Uhd Nielsen, C. (eds.). London: Pharmaceutical Press, p. 193-211 (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. Published

    Acetylcholine

    Jensen, Anders A. & Krogsgaard-Larsen, Povl, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 263-281

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  48. Published

    Acetylcholinesterase inhibitory activity of lycopodane-type alkaloids from the Icelandic Lycopodium annotinum ssp. alpestre

    Halldórsdóttir, E. S., Jaroszewski, J. W. & Olafsdottir, E. S., 2010, In: Phytochemistry. 71, 2-3, p. 149-157

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Adolescents' medicine use: a response to strain

    Holstein, B., Hansen, E. H., Iannotti, R., Andersen, A. & Tobi, H., 2010, In: International Journal of Behavioral Medicine. 17, Suppl. 1, p. s20

    Research output: Contribution to journalConference abstract in journalResearch

  50. Published

    Adverse drug reactions from psychotropic medicines in the paediatric population: analysis of reports to the Danish Medicines Agency over a decade

    Aagaard, L. & Hansen, E. H., 2010, In: BMC Research Notes. 3, p. 176 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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