Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler
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Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler. / Jørgensen, Anders W; Hilden, Jørgen; Gøtzsche, Peter C.
In: Ugeskrift for læger, Vol. 168, No. 48, 2006, p. 4218-20.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Cochraneoversigter sammenlignet med firmastøttede og andre metaanalyser af de samme laegemidler
AU - Jørgensen, Anders W
AU - Hilden, Jørgen
AU - Gøtzsche, Peter C
PY - 2006
Y1 - 2006
N2 - 24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution. Udgivelsesdato: 2006-Nov-27
AB - 24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution. Udgivelsesdato: 2006-Nov-27
M3 - Tidsskriftartikel
C2 - 17147949
VL - 168
SP - 4218
EP - 4220
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 48
ER -
ID: 14309210