Deficient maturation of aspects of attention and executive functions in early onset schizophrenia

Research output: Contribution to journalJournal articleResearchpeer-review

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Deficient maturation of aspects of attention and executive functions in early onset schizophrenia. / Jepsen, Jens Richardt M; Fagerlund, Birgitte; Pagsberg, Anne Katrine; Christensen, Anne Marie R; Nordentoft, Merete; Mortensen, Erik L; Jepsen, Jens Richardt M; Fagerlund, Birgitte; Pagsberg, Anne Katrine; Christensen, Anne Marie R; Nordentoft, Merete; Mortensen, Erik Lykke.

In: European Child & Adolescent Psychiatry, 01.08.2010.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Jepsen, JRM, Fagerlund, B, Pagsberg, AK, Christensen, AMR, Nordentoft, M, Mortensen, EL, Jepsen, JRM, Fagerlund, B, Pagsberg, AK, Christensen, AMR, Nordentoft, M & Mortensen, EL 2010, 'Deficient maturation of aspects of attention and executive functions in early onset schizophrenia', European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-010-0126-4, https://doi.org/10.1007/s00787-010-0126-4

APA

Jepsen, J. R. M., Fagerlund, B., Pagsberg, A. K., Christensen, A. M. R., Nordentoft, M., Mortensen, E. L., Jepsen, J. R. M., Fagerlund, B., Pagsberg, A. K., Christensen, A. M. R., Nordentoft, M., & Mortensen, E. L. (2010). Deficient maturation of aspects of attention and executive functions in early onset schizophrenia. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-010-0126-4, https://doi.org/10.1007/s00787-010-0126-4

Vancouver

Jepsen JRM, Fagerlund B, Pagsberg AK, Christensen AMR, Nordentoft M, Mortensen EL et al. Deficient maturation of aspects of attention and executive functions in early onset schizophrenia. European Child & Adolescent Psychiatry. 2010 Aug 1. https://doi.org/10.1007/s00787-010-0126-4, https://doi.org/10.1007/s00787-010-0126-4

Author

Jepsen, Jens Richardt M ; Fagerlund, Birgitte ; Pagsberg, Anne Katrine ; Christensen, Anne Marie R ; Nordentoft, Merete ; Mortensen, Erik L ; Jepsen, Jens Richardt M ; Fagerlund, Birgitte ; Pagsberg, Anne Katrine ; Christensen, Anne Marie R ; Nordentoft, Merete ; Mortensen, Erik Lykke. / Deficient maturation of aspects of attention and executive functions in early onset schizophrenia. In: European Child & Adolescent Psychiatry. 2010.

Bibtex

@article{0bc85580d2bb11df825b000ea68e967b,
title = "Deficient maturation of aspects of attention and executive functions in early onset schizophrenia",
abstract = "The few existing long-term, neuropsychological follow-up studies of early onset schizophrenia (EOS) patients have reported relative stability in some cognitive functions but abnormal developmental trajectories in verbal memory, set shifting, aspects of attention, and speed of information processing throughout late adolescence into early adulthood. The current 5-year follow-up study compared the development of specific cognitive functions in EOS patients (N = 17) from the time of first-episode to chronic phase with that of healthy controls (N = 38) and secondarily to patients with other early onset, non-organic, non-affective psychoses (EOP) (N = 11). Speed of processing of executive functions, set shifting, and attention improved significantly in the healthy controls and reflected continuous functional maturation during late adolescence and early adulthood. The developmental progression of attention and set shifting but not speed of processing of executive functions was significantly subnormal in EOS patients. Other specific cognitive functions that had attained functional maturity in the healthy controls before or around the time of the baseline assessment showed normal development in EOS patients during the follow-up period, indicating stable cognitive deficits. These results suggest post-onset developmental deficits in two out of the three aspects of attention and executive functions that have protracted maturational trajectories and that overlap the age of onset of EOS. No significant difference in the development of any specific cognitive function was found between the EOS and EOP group.",
author = "Jepsen, {Jens Richardt M} and Birgitte Fagerlund and Pagsberg, {Anne Katrine} and Christensen, {Anne Marie R} and Merete Nordentoft and Mortensen, {Erik L} and Jepsen, {Jens Richardt M} and Birgitte Fagerlund and Pagsberg, {Anne Katrine} and Christensen, {Anne Marie R} and Merete Nordentoft and Mortensen, {Erik Lykke}",
year = "2010",
month = aug,
day = "1",
doi = "10.1007/s00787-010-0126-4",
language = "English",
journal = "European Child & Adolescent Psychiatry",
issn = "1018-8827",
publisher = "Springer Medizin",

}

RIS

TY - JOUR

T1 - Deficient maturation of aspects of attention and executive functions in early onset schizophrenia

AU - Jepsen, Jens Richardt M

AU - Fagerlund, Birgitte

AU - Pagsberg, Anne Katrine

AU - Christensen, Anne Marie R

AU - Nordentoft, Merete

AU - Mortensen, Erik L

AU - Jepsen, Jens Richardt M

AU - Fagerlund, Birgitte

AU - Pagsberg, Anne Katrine

AU - Christensen, Anne Marie R

AU - Nordentoft, Merete

AU - Mortensen, Erik Lykke

PY - 2010/8/1

Y1 - 2010/8/1

N2 - The few existing long-term, neuropsychological follow-up studies of early onset schizophrenia (EOS) patients have reported relative stability in some cognitive functions but abnormal developmental trajectories in verbal memory, set shifting, aspects of attention, and speed of information processing throughout late adolescence into early adulthood. The current 5-year follow-up study compared the development of specific cognitive functions in EOS patients (N = 17) from the time of first-episode to chronic phase with that of healthy controls (N = 38) and secondarily to patients with other early onset, non-organic, non-affective psychoses (EOP) (N = 11). Speed of processing of executive functions, set shifting, and attention improved significantly in the healthy controls and reflected continuous functional maturation during late adolescence and early adulthood. The developmental progression of attention and set shifting but not speed of processing of executive functions was significantly subnormal in EOS patients. Other specific cognitive functions that had attained functional maturity in the healthy controls before or around the time of the baseline assessment showed normal development in EOS patients during the follow-up period, indicating stable cognitive deficits. These results suggest post-onset developmental deficits in two out of the three aspects of attention and executive functions that have protracted maturational trajectories and that overlap the age of onset of EOS. No significant difference in the development of any specific cognitive function was found between the EOS and EOP group.

AB - The few existing long-term, neuropsychological follow-up studies of early onset schizophrenia (EOS) patients have reported relative stability in some cognitive functions but abnormal developmental trajectories in verbal memory, set shifting, aspects of attention, and speed of information processing throughout late adolescence into early adulthood. The current 5-year follow-up study compared the development of specific cognitive functions in EOS patients (N = 17) from the time of first-episode to chronic phase with that of healthy controls (N = 38) and secondarily to patients with other early onset, non-organic, non-affective psychoses (EOP) (N = 11). Speed of processing of executive functions, set shifting, and attention improved significantly in the healthy controls and reflected continuous functional maturation during late adolescence and early adulthood. The developmental progression of attention and set shifting but not speed of processing of executive functions was significantly subnormal in EOS patients. Other specific cognitive functions that had attained functional maturity in the healthy controls before or around the time of the baseline assessment showed normal development in EOS patients during the follow-up period, indicating stable cognitive deficits. These results suggest post-onset developmental deficits in two out of the three aspects of attention and executive functions that have protracted maturational trajectories and that overlap the age of onset of EOS. No significant difference in the development of any specific cognitive function was found between the EOS and EOP group.

U2 - 10.1007/s00787-010-0126-4

DO - 10.1007/s00787-010-0126-4

M3 - Journal article

C2 - 20680364

JO - European Child & Adolescent Psychiatry

JF - European Child & Adolescent Psychiatry

SN - 1018-8827

ER -

ID: 22387194