Differential nongenetic impact of birth weight versus third-trimester growth velocity on glucose metabolism and magnetic resonance imaging abdominal obesity in young healthy twins
Research output: Contribution to journal › Journal article › Research › peer-review
Kasper Pilgaard, Thomas Hammershaimb Mosbech, Louise Grunnet, Hans Eiberg, Gerrit Van Hall, Eva Fallentin, Torben Kjeldgaard Larsen, Rasmus Larsen, Pernille Poulsen, Allan Vaag
Low birth weight is associated with type 2 diabetes, which to some extent may be mediated via abdominal adiposity and insulin resistance. Fetal growth velocity is high during the third trimester, constituting a potential critical window for organ programming. Intra-pair differences among monozygotic twins are instrumental in determining nongenetic associations between early environment and adult metabolic phenotype.
| Original language | English |
|---|---|
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 96 |
| Issue number | 9 |
| Pages (from-to) | 2835-43 |
| Number of pages | 9 |
| ISSN | 0021-972X |
| DOIs | |
| Publication status | Published - 2011 |
- Adolescent, Birth Weight, Body Composition, Female, Glucose, Glucose Clamp Technique, Humans, Infant, Low Birth Weight, Infant, Newborn, Insulin, Insulin Resistance, Male, Obesity, Abdominal, Sex Factors, Twins, Young Adult
Research areas
ID: 38489510