Effect of sex, age, and race on the clinical presentation of tuberculosis: A 15-year population-based study
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Effect of sex, age, and race on the clinical presentation of tuberculosis : A 15-year population-based study. / Zhang, Xinyu; Andersen, Aase B.; Lillebaek, Troels; Kamper-Jørgensen, Zaza; Thomsen, Vibeke Østergaard; Ladefoged, Karin; Marrs, Carl F.; Zhang, Lixin; Yang, Zhenhua.
In: American Journal of Tropical Medicine and Hygiene, Vol. 85, No. 2, 08.2011, p. 285-290.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Effect of sex, age, and race on the clinical presentation of tuberculosis
T2 - A 15-year population-based study
AU - Zhang, Xinyu
AU - Andersen, Aase B.
AU - Lillebaek, Troels
AU - Kamper-Jørgensen, Zaza
AU - Thomsen, Vibeke Østergaard
AU - Ladefoged, Karin
AU - Marrs, Carl F.
AU - Zhang, Lixin
AU - Yang, Zhenhua
PY - 2011/8
Y1 - 2011/8
N2 - Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenland during 1992-2007 to gain insight to the role of host factors in EPTB pathogenesis. Among patients from Somalia and Asia, persons 25-44 and 45-64 years of age were more likely to have EPTB than persons 15-24 years of age. In contrast, among persons from Greenland, the two oldest age groups were significantly less likely to have EPTB than the youngest age group. For all the age groups, the odds for having EPTB was significantly higher among patients from Somalia and Asia and significantly lower among the patients from Greenland than among patients from Denmark. Furthermore, the occurrence of specific types of EPTB significantly varied among different age groups or origins.
AB - Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenland during 1992-2007 to gain insight to the role of host factors in EPTB pathogenesis. Among patients from Somalia and Asia, persons 25-44 and 45-64 years of age were more likely to have EPTB than persons 15-24 years of age. In contrast, among persons from Greenland, the two oldest age groups were significantly less likely to have EPTB than the youngest age group. For all the age groups, the odds for having EPTB was significantly higher among patients from Somalia and Asia and significantly lower among the patients from Greenland than among patients from Denmark. Furthermore, the occurrence of specific types of EPTB significantly varied among different age groups or origins.
UR - http://www.scopus.com/inward/record.url?scp=80051484433&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2011.10-0630
DO - 10.4269/ajtmh.2011.10-0630
M3 - Journal article
C2 - 21813849
AN - SCOPUS:80051484433
VL - 85
SP - 285
EP - 290
JO - Journal. National Malaria Society
JF - Journal. National Malaria Society
SN - 0002-9637
IS - 2
ER -
ID: 247164526