Estimation from current-status data in continuous time
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Estimation from current-status data in continuous time. / Keiding, Niels; Begtrup, Kamilla; Scheike, Thomas H.; Hasibeder, Günther.
In: Lifetime Data Analysis, Vol. 2, No. 2, 06.1996, p. 119-129.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Estimation from current-status data in continuous time
AU - Keiding, Niels
AU - Begtrup, Kamilla
AU - Scheike, Thomas H.
AU - Hasibeder, Günther
PY - 1996/6
Y1 - 1996/6
N2 - The nonparametric maximum likelihood estimator for current-status data has been known for at least 40 years, but only recently have the mathematical-statistical properties been clarified. This note provides a case study in the important and often studied context of estimating age-specific immunization intensities from a seroprevalence survey. Fully parametric and spline-based alternatives (also based on continuous-time models) are given. The basic reproduction number R0 exemplifies estimation of a functional. The limitations implied by the necessarily rather restrictive epidemiological assumptions are briefly discussed.
AB - The nonparametric maximum likelihood estimator for current-status data has been known for at least 40 years, but only recently have the mathematical-statistical properties been clarified. This note provides a case study in the important and often studied context of estimating age-specific immunization intensities from a seroprevalence survey. Fully parametric and spline-based alternatives (also based on continuous-time models) are given. The basic reproduction number R0 exemplifies estimation of a functional. The limitations implied by the necessarily rather restrictive epidemiological assumptions are briefly discussed.
KW - Age-specific incidence
KW - Basic reproduction number
KW - Epidemiology
KW - Smoothing splines
KW - Weibull survival distribution
UR - http://www.scopus.com/inward/record.url?scp=0030321329&partnerID=8YFLogxK
U2 - 10.1007/BF00128570
DO - 10.1007/BF00128570
M3 - Journal article
C2 - 9384639
AN - SCOPUS:0030321329
VL - 2
SP - 119
EP - 129
JO - Lifetime Data Analysis
JF - Lifetime Data Analysis
SN - 1380-7870
IS - 2
ER -
ID: 201613622