European study showed that children with congenital anomalies often underwent multiple surgical procedures at different ages across Europe
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European study showed that children with congenital anomalies often underwent multiple surgical procedures at different ages across Europe. / Garne, Ester; Loane, Maria; Tan, Joachim; Ballardini, Elisa; Brigden, Joanna; Cavero-Carbonell, Clara; Coi, Alessio; Damkjaer, Mads; Garcia-Villodre, Laura; Gissler, Mika; Given, Joanne; Heino, Anna; Jordan, Sue; Limb, Elizabeth; Neville, Amanda; Rissmann, Anke; Santoro, Michele; Scanlon, Ieuan; Urhoj, Stine Kjaer; Wellesley, Diana; Morris, Joan.
In: Acta paediatrica (Oslo, Norway : 1992), Vol. 112, No. 6, 2023, p. 1304-1311.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - European study showed that children with congenital anomalies often underwent multiple surgical procedures at different ages across Europe
AU - Garne, Ester
AU - Loane, Maria
AU - Tan, Joachim
AU - Ballardini, Elisa
AU - Brigden, Joanna
AU - Cavero-Carbonell, Clara
AU - Coi, Alessio
AU - Damkjaer, Mads
AU - Garcia-Villodre, Laura
AU - Gissler, Mika
AU - Given, Joanne
AU - Heino, Anna
AU - Jordan, Sue
AU - Limb, Elizabeth
AU - Neville, Amanda
AU - Rissmann, Anke
AU - Santoro, Michele
AU - Scanlon, Ieuan
AU - Urhoj, Stine Kjaer
AU - Wellesley, Diana
AU - Morris, Joan
N1 - This article is protected by copyright. All rights reserved.
PY - 2023
Y1 - 2023
N2 - AIM: Children with congenital anomalies often require surgery but data on the burden of surgery for these children are limited.METHODS: A population-based record-linkage study in Finland, Wales and regions of Denmark, England, Italy and Spain. A total of 91,504 children with congenital anomalies born in 1995-2014 were followed to their tenth birthday or the end of 2015. Electronic linkage to hospital databases provided data on in-patient surgical procedures and meta-analyses of surgical procedures were performed by age groups.RESULTS: The percentage of children having surgery in the first year was 38% with some differences across regions and 14% also underwent surgery at age 1-4 years. Regional differences in age at the time of their first surgical procedure were observed for children with cleft palate, hydronephrosis, hypospadias, clubfoot and craniosynostosis. The children had a median of 2.0 (95%CI1.98,2.02) surgical procedures before age five years with children with oesophageal atresia having the highest median number of procedures (4.5; 95% CI 3.3, 5.8).CONCLUSION: A third of children with congenital anomalies required surgery during infancy and often more than one procedure was needed before age five years. There was no European consensus on the preferred age for surgery for some anomalies.
AB - AIM: Children with congenital anomalies often require surgery but data on the burden of surgery for these children are limited.METHODS: A population-based record-linkage study in Finland, Wales and regions of Denmark, England, Italy and Spain. A total of 91,504 children with congenital anomalies born in 1995-2014 were followed to their tenth birthday or the end of 2015. Electronic linkage to hospital databases provided data on in-patient surgical procedures and meta-analyses of surgical procedures were performed by age groups.RESULTS: The percentage of children having surgery in the first year was 38% with some differences across regions and 14% also underwent surgery at age 1-4 years. Regional differences in age at the time of their first surgical procedure were observed for children with cleft palate, hydronephrosis, hypospadias, clubfoot and craniosynostosis. The children had a median of 2.0 (95%CI1.98,2.02) surgical procedures before age five years with children with oesophageal atresia having the highest median number of procedures (4.5; 95% CI 3.3, 5.8).CONCLUSION: A third of children with congenital anomalies required surgery during infancy and often more than one procedure was needed before age five years. There was no European consensus on the preferred age for surgery for some anomalies.
U2 - 10.1111/apa.16726
DO - 10.1111/apa.16726
M3 - Journal article
C2 - 36823678
VL - 112
SP - 1304
EP - 1311
JO - Acta Paediatrica
JF - Acta Paediatrica
SN - 0803-5253
IS - 6
ER -
ID: 338169986