False-positive Human Papillomavirus DNA tests in cervical screening: it is all in a definition
Research output: Contribution to journal › Journal article
Based on data from randomised controlled trials (RCT) on primary cervical screening, it has been reported that the problem of more frequent false-positive tests in Human Papillomavirus (HPV) DNA screening compared to cytology could be overcome. However, these reports predominantly operated with a narrow definition of a (false-)positive test. The aim of this paper was to illustrate how the narrow definition affected the measured adverse effects of HPV DNA screening compared with cytology screening.
|Journal||European Journal of Cancer|
|Number of pages||7|
|Publication status||Published - Jan 2011|
- Adult, Cervical Intraepithelial Neoplasia, DNA, Viral, Early Detection of Cancer, False Positive Reactions, Female, Humans, Middle Aged, Papillomaviridae, Papillomavirus Infections, Randomized Controlled Trials as Topic, Sensitivity and Specificity, Uterine Cervical Neoplasms, Vaginal Smears