False-positive Human Papillomavirus DNA tests in cervical screening: it is all in a definition

Research output: Contribution to journalJournal articleResearchpeer-review

Matejka Rebolj, Igor Pribac, Elsebeth Lynge

Based on data from randomised controlled trials (RCT) on primary cervical screening, it has been reported that the problem of more frequent false-positive tests in Human Papillomavirus (HPV) DNA screening compared to cytology could be overcome. However, these reports predominantly operated with a narrow definition of a (false-)positive test. The aim of this paper was to illustrate how the narrow definition affected the measured adverse effects of HPV DNA screening compared with cytology screening.
Original languageEnglish
JournalEuropean Journal of Cancer
Volume47
Issue number2
Pages (from-to)255-261
Number of pages7
ISSN0959-8049
DOIs
Publication statusPublished - Jan 2011

    Research areas

  • Adult, Cervical Intraepithelial Neoplasia, DNA, Viral, Early Detection of Cancer, False Positive Reactions, Female, Humans, Middle Aged, Papillomaviridae, Papillomavirus Infections, Randomized Controlled Trials as Topic, Sensitivity and Specificity, Uterine Cervical Neoplasms, Vaginal Smears

ID: 38295609