Genome-wide association study identifies four loci associated with eruption of permanent teeth

Research output: Contribution to journalJournal articleResearchpeer-review

  • Frank Geller
  • Bjarke Feenstra
  • Hao Zhang
  • John R Shaffer
  • Thomas Hansen
  • Ann-Louise Esserlind
  • Heather A Boyd
  • Ellen A Nohr
  • Nicholas J Timpson
  • Ghazaleh Fatemifar
  • Lavinia Paternoster
  • David M Evans
  • Robert J Weyant
  • Steven M Levy
  • Mark Lathrop
  • George Davey Smith
  • Jeffrey C Murray
  • Mary L Marazita
  • Mads Melbye
The sequence and timing of permanent tooth eruption is thought to be highly heritable and can have important implications for the risk of malocclusion, crowding, and periodontal disease. We conducted a genome-wide association study of number of permanent teeth erupted between age 6 and 14 years, analyzed as age-adjusted standard deviation score averaged over multiple time points, based on childhood records for 5,104 women from the Danish National Birth Cohort. Four loci showed association at P
Original languageEnglish
JournalP L o S Genetics
Volume7
Issue number9
Pages (from-to)e1002275
ISSN1553-7390
DOIs
Publication statusPublished - 1 Sep 2011

ID: 40186795