TY - JOUR

T1 - Insulin Pump Treatment in Adults with Type 1 Diabetes in the Capital Region of Denmark

T2 - Design and Cohort Characteristics of the Steno Tech Survey

AU - Rytter, Karen

AU - Madsen, Kristoffer P.

AU - Andersen, Henrik U.

AU - Cleal, Bryan

AU - Hommel, Eva

AU - Nexo, Mette A.

AU - Pedersen-Bjergaard, Ulrik

AU - Skinner, Timothy

AU - Willaing, Ingrid

AU - Norgaard, Kirsten

AU - Schmidt, Signe

PY - 2022

Y1 - 2022

N2 - IntroductionInsulin pump therapy can improve quality of life and glycaemic outcomes for many people with type 1 diabetes (T1D). The multidimensional Steno Tech Survey study aims to investigate why some insulin pump users do not achieve treatment goals. In this article, we present the study design and analyse differences in population characteristics between responders and non-responders.MethodsIn June 2020, all 1591 insulin pump users (≥ 18 years) in the Capital Region of Denmark were invited to participate in an online questionnaire that evaluated several dimensions of insulin pump self-management and psychosocial health. Demographic, socioeconomic and clinical characteristics, including age, sex and HbA1c, of the cohort were identified via national registries. Predictors of questionnaire response/non-response were explored with logistic regression analysis.ResultsIn the full study population, 58% were female, median age was 42 years and median HbA1c was 58 mmol/mol (7.5%); 30% had HbA1c < 53 mmol/mol (7.0%). In total, 770 individuals (48%) responded to the questionnaire. Logistic regression analysis showed that 50+ years of age (odds ratio [OR] = 2.3, 95% confidence interval [CI]: 1.4–3.8), female sex (OR = 1.3, CI: 1.02–1.6), being married (OR = 1.8, CI: 1.3–2.4) and having long higher education (OR = 1.6, CI: 1.004–2.5) were significantly associated with a higher likelihood of responding to the survey; the opposite was found for HbA1c from 64 to < 75 mmol (8.0–9.0%) (OR = 0.6, CI: 0.4–0.8) and HbA1c ≥ 75 mmol/mol (≥ 9.0%) (OR = 0.2, CI: 0.1–0.3).ConclusionsThe established Steno Tech cohort enables future analysis of a range of psychosocial and behavioural aspects of insulin pump self-management. Interpretation and generalization of findings should consider observed differences between responders and non-responders.

AB - IntroductionInsulin pump therapy can improve quality of life and glycaemic outcomes for many people with type 1 diabetes (T1D). The multidimensional Steno Tech Survey study aims to investigate why some insulin pump users do not achieve treatment goals. In this article, we present the study design and analyse differences in population characteristics between responders and non-responders.MethodsIn June 2020, all 1591 insulin pump users (≥ 18 years) in the Capital Region of Denmark were invited to participate in an online questionnaire that evaluated several dimensions of insulin pump self-management and psychosocial health. Demographic, socioeconomic and clinical characteristics, including age, sex and HbA1c, of the cohort were identified via national registries. Predictors of questionnaire response/non-response were explored with logistic regression analysis.ResultsIn the full study population, 58% were female, median age was 42 years and median HbA1c was 58 mmol/mol (7.5%); 30% had HbA1c < 53 mmol/mol (7.0%). In total, 770 individuals (48%) responded to the questionnaire. Logistic regression analysis showed that 50+ years of age (odds ratio [OR] = 2.3, 95% confidence interval [CI]: 1.4–3.8), female sex (OR = 1.3, CI: 1.02–1.6), being married (OR = 1.8, CI: 1.3–2.4) and having long higher education (OR = 1.6, CI: 1.004–2.5) were significantly associated with a higher likelihood of responding to the survey; the opposite was found for HbA1c from 64 to < 75 mmol (8.0–9.0%) (OR = 0.6, CI: 0.4–0.8) and HbA1c ≥ 75 mmol/mol (≥ 9.0%) (OR = 0.2, CI: 0.1–0.3).ConclusionsThe established Steno Tech cohort enables future analysis of a range of psychosocial and behavioural aspects of insulin pump self-management. Interpretation and generalization of findings should consider observed differences between responders and non-responders.

KW - HbA1c

KW - Insulin pump

KW - National registries

KW - Response

KW - non-response

KW - Survey

KW - Type 1 diabetes

U2 - 10.1007/s13300-021-01181-0

DO - 10.1007/s13300-021-01181-0

M3 - Journal article

C2 - 34807407

VL - 13

SP - 113

EP - 129

JO - Diabetes Therapy

JF - Diabetes Therapy

SN - 1869-6953

ER -