TY - JOUR

T1 - Intensive community pharmacy intervention had little impact on triptan consumption

T2 - A randomized controlled trial

AU - Søndergaard, Jens

AU - Foged, Annette

AU - Kragstrup, Jakob

AU - Gaist, David

AU - Gram, Lars Freng

AU - Sindrup, Søren Hein

AU - Schaffalizky De Muckadell, Hans Ulrik

AU - Larsen, Bente Overgaard

AU - Herborg, Hanne

AU - Andersen, Morten

N1 - Funding Information: The authors would like to thank the pharmacies for their participation in the trial. The study was supported by The Danish Pharmacy Foundation (Apotekerfonden).

PY - 2006/3

Y1 - 2006/3

N2 - Objective. To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans. Design. Randomized controlled trial. Setting. 22 community pharmacies in the County of Funen, Denmark. Subjects. A total of 1123 triptan users at intervention pharmacies and 1340 at control pharmacies. Intervention. Intervention pharmacy staff received information on migraine and other types of headache, detection of inappropriate triptan use and other drug-related problems, and techniques for establishing a dialogue with patients. Intervention consisted of a folder and a structured dialogue with the pharmacy staff. The folder included questions aimed at detecting overuse and inappropriate triptan use. Main outcome measures. Change in average triptan consumption in doses per month measured by means of a prescription database with information on all purchases of reimbursed drugs at the level of the individual patient. Results. Overall, intervention had no statistically significant short-term impact on patients' consumption of triptans either among incident users (intervention/control ratio 1.02; 95% confidence interval 0.95 to 1.12), or among prevalent users (1.02; 0.97 to 1.08). No effects were observed after 6 and 9 months, apart from a possible borderline effect after 9 months among prevalent users with intermediate triptan consumption (0.93; 0.87 to 1.00). Conclusion. The pharmaceutical care campaign did not reduce the use of triptans.

AB - Objective. To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans. Design. Randomized controlled trial. Setting. 22 community pharmacies in the County of Funen, Denmark. Subjects. A total of 1123 triptan users at intervention pharmacies and 1340 at control pharmacies. Intervention. Intervention pharmacy staff received information on migraine and other types of headache, detection of inappropriate triptan use and other drug-related problems, and techniques for establishing a dialogue with patients. Intervention consisted of a folder and a structured dialogue with the pharmacy staff. The folder included questions aimed at detecting overuse and inappropriate triptan use. Main outcome measures. Change in average triptan consumption in doses per month measured by means of a prescription database with information on all purchases of reimbursed drugs at the level of the individual patient. Results. Overall, intervention had no statistically significant short-term impact on patients' consumption of triptans either among incident users (intervention/control ratio 1.02; 95% confidence interval 0.95 to 1.12), or among prevalent users (1.02; 0.97 to 1.08). No effects were observed after 6 and 9 months, apart from a possible borderline effect after 9 months among prevalent users with intermediate triptan consumption (0.93; 0.87 to 1.00). Conclusion. The pharmaceutical care campaign did not reduce the use of triptans.

KW - Community pharmacy service

KW - Drug therapy

KW - Drug utilization

KW - Humans

KW - Migraine

KW - Pharmaceutical services

KW - Pharmacists

KW - Physicians' practice patterns

KW - Prescribing

KW - Primary healthcare

KW - Randomized controlled trials

KW - Research

KW - Serotonin agonists

KW - Tension headache

UR - http://www.scopus.com/inward/record.url?scp=32344434736&partnerID=8YFLogxK

U2 - 10.1080/02813430500444916

DO - 10.1080/02813430500444916

M3 - Journal article

C2 - 16464810

AN - SCOPUS:32344434736

VL - 24

SP - 16

EP - 21

JO - Scandinavian Journal of Primary Health Care

JF - Scandinavian Journal of Primary Health Care

SN - 0281-3432

IS - 1

ER -