Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?

Research output: Contribution to journalJournal articleResearchpeer-review

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Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents? / Greve, Aja Neergaard; Mors, Ole; Mortensen, Erik Lykke; Meier, Sandra Melanie; McGrath, John J.; Petersen, Liselotte.

In: Schizophrenia Research: Cognition, Vol. 9, 09.2017, p. 18-22.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Greve, AN, Mors, O, Mortensen, EL, Meier, SM, McGrath, JJ & Petersen, L 2017, 'Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?', Schizophrenia Research: Cognition, vol. 9, pp. 18-22. https://doi.org/10.1016/j.scog.2017.07.001

APA

Greve, A. N., Mors, O., Mortensen, E. L., Meier, S. M., McGrath, J. J., & Petersen, L. (2017). Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents? Schizophrenia Research: Cognition, 9, 18-22. https://doi.org/10.1016/j.scog.2017.07.001

Vancouver

Greve AN, Mors O, Mortensen EL, Meier SM, McGrath JJ, Petersen L. Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents? Schizophrenia Research: Cognition. 2017 Sep;9:18-22. https://doi.org/10.1016/j.scog.2017.07.001

Author

Greve, Aja Neergaard ; Mors, Ole ; Mortensen, Erik Lykke ; Meier, Sandra Melanie ; McGrath, John J. ; Petersen, Liselotte. / Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?. In: Schizophrenia Research: Cognition. 2017 ; Vol. 9. pp. 18-22.

Bibtex

@article{aecc17a3d16947699738b804b1a8d5ec,
title = "Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?",
abstract = "Results from twin, family, and adoption studies all suggest that general intelligence is highly heritable. Several studies have shown lower premorbid intelligence in individuals before the onset of both mood disorders and psychosis, as well as in children and adolescents at genetic high risk for developing schizophrenia. Based on these findings, we aim to investigate if the association between educational achievement in parents and intelligence in their offspring is influenced by schizophrenia or mood disorder in parents. In a large population-based sample of young adult male conscripts (n = 156,531) the presence of a mental disorder in the parents were associated with significantly lower offspring scores on a test of general intelligence, the B{\o}rge Priens Pr{\o}ve (BPP), and higher educational attainment in parents was significantly associated with higher BPP test scores in offspring. A significant interaction suggested that the positive association between maternal education and offspring intelligence was stronger in offspring of mothers with schizophrenia compared to the control group (p = 0.03). The associations between parental education and offspring intelligence are also observed when restricting the sample to conscripts whose parents are diagnosed after 30 years of age. In conclusion, findings from this study show a more positive effect of education on offspring intelligence in mothers with schizophrenia compared to mothers from the control group. This effect could have both environmental and genetic explanations.",
keywords = "Educational attainment, General cognitive ability, Intelligence, Mood disorder, Schizophrenia",
author = "Greve, {Aja Neergaard} and Ole Mors and Mortensen, {Erik Lykke} and Meier, {Sandra Melanie} and McGrath, {John J.} and Liselotte Petersen",
year = "2017",
month = "9",
doi = "10.1016/j.scog.2017.07.001",
language = "English",
volume = "9",
pages = "18--22",
journal = "Schizophrenia Research: Cognition",
issn = "2215-0013",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?

AU - Greve, Aja Neergaard

AU - Mors, Ole

AU - Mortensen, Erik Lykke

AU - Meier, Sandra Melanie

AU - McGrath, John J.

AU - Petersen, Liselotte

PY - 2017/9

Y1 - 2017/9

N2 - Results from twin, family, and adoption studies all suggest that general intelligence is highly heritable. Several studies have shown lower premorbid intelligence in individuals before the onset of both mood disorders and psychosis, as well as in children and adolescents at genetic high risk for developing schizophrenia. Based on these findings, we aim to investigate if the association between educational achievement in parents and intelligence in their offspring is influenced by schizophrenia or mood disorder in parents. In a large population-based sample of young adult male conscripts (n = 156,531) the presence of a mental disorder in the parents were associated with significantly lower offspring scores on a test of general intelligence, the Børge Priens Prøve (BPP), and higher educational attainment in parents was significantly associated with higher BPP test scores in offspring. A significant interaction suggested that the positive association between maternal education and offspring intelligence was stronger in offspring of mothers with schizophrenia compared to the control group (p = 0.03). The associations between parental education and offspring intelligence are also observed when restricting the sample to conscripts whose parents are diagnosed after 30 years of age. In conclusion, findings from this study show a more positive effect of education on offspring intelligence in mothers with schizophrenia compared to mothers from the control group. This effect could have both environmental and genetic explanations.

AB - Results from twin, family, and adoption studies all suggest that general intelligence is highly heritable. Several studies have shown lower premorbid intelligence in individuals before the onset of both mood disorders and psychosis, as well as in children and adolescents at genetic high risk for developing schizophrenia. Based on these findings, we aim to investigate if the association between educational achievement in parents and intelligence in their offspring is influenced by schizophrenia or mood disorder in parents. In a large population-based sample of young adult male conscripts (n = 156,531) the presence of a mental disorder in the parents were associated with significantly lower offspring scores on a test of general intelligence, the Børge Priens Prøve (BPP), and higher educational attainment in parents was significantly associated with higher BPP test scores in offspring. A significant interaction suggested that the positive association between maternal education and offspring intelligence was stronger in offspring of mothers with schizophrenia compared to the control group (p = 0.03). The associations between parental education and offspring intelligence are also observed when restricting the sample to conscripts whose parents are diagnosed after 30 years of age. In conclusion, findings from this study show a more positive effect of education on offspring intelligence in mothers with schizophrenia compared to mothers from the control group. This effect could have both environmental and genetic explanations.

KW - Educational attainment

KW - General cognitive ability

KW - Intelligence

KW - Mood disorder

KW - Schizophrenia

UR - http://www.scopus.com/inward/record.url?scp=85025805116&partnerID=8YFLogxK

U2 - 10.1016/j.scog.2017.07.001

DO - 10.1016/j.scog.2017.07.001

M3 - Journal article

C2 - 28868239

AN - SCOPUS:85025805116

VL - 9

SP - 18

EP - 22

JO - Schizophrenia Research: Cognition

JF - Schizophrenia Research: Cognition

SN - 2215-0013

ER -

ID: 188962093