Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion

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Standard

Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. / Johansen, A; Nielsen, E-M D; Andersen, G; Hamid, Y H; Jensen, D P; Glümer, C; Drivsholm, T; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Pedersen, O.

In: Diabetologia, Vol. 47, No. 8, 01.08.2004, p. 1437-41.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Johansen, A, Nielsen, E-MD, Andersen, G, Hamid, YH, Jensen, DP, Glümer, C, Drivsholm, T, Borch-Johnsen, K, Jørgensen, T, Hansen, T & Pedersen, O 2004, 'Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion', Diabetologia, vol. 47, no. 8, pp. 1437-41. https://doi.org/10.1007/s00125-004-1459-7

APA

Johansen, A., Nielsen, E-M. D., Andersen, G., Hamid, Y. H., Jensen, D. P., Glümer, C., Drivsholm, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T., & Pedersen, O. (2004). Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. Diabetologia, 47(8), 1437-41. https://doi.org/10.1007/s00125-004-1459-7

Vancouver

Johansen A, Nielsen E-MD, Andersen G, Hamid YH, Jensen DP, Glümer C et al. Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. Diabetologia. 2004 Aug 1;47(8):1437-41. https://doi.org/10.1007/s00125-004-1459-7

Author

Johansen, A ; Nielsen, E-M D ; Andersen, G ; Hamid, Y H ; Jensen, D P ; Glümer, C ; Drivsholm, T ; Borch-Johnsen, K ; Jørgensen, T ; Hansen, T ; Pedersen, O. / Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion. In: Diabetologia. 2004 ; Vol. 47, No. 8. pp. 1437-41.

Bibtex

@article{530b26e21c4f4bb89a2466da1d9bd1df,
title = "Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion",
abstract = "Polymorphisms of the butyrylcholinesterase gene (BCHE) are reported to associate with Alzheimer's disease and a recent study found a significant association of the BCHE K variant (G1615A/Ala539Thr) with Type 2 diabetes. The objectives of our study were to examine whether the BCHE K variant is associated with Type 2 diabetes or estimates of pancreatic beta cell function in large-scale populations of glucose-tolerant Caucasians.",
keywords = "Amino Acid Substitution, Base Sequence, Blood Glucose, Butyrylcholinesterase, DNA Primers, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Variation, Genotype, Humans, Insulin, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Polymorphism, Single Nucleotide, Reference Values",
author = "A Johansen and Nielsen, {E-M D} and G Andersen and Hamid, {Y H} and Jensen, {D P} and C Gl{\"u}mer and T Drivsholm and K Borch-Johnsen and T J{\o}rgensen and T Hansen and O Pedersen",
year = "2004",
month = aug,
day = "1",
doi = "10.1007/s00125-004-1459-7",
language = "English",
volume = "47",
pages = "1437--41",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "8",

}

RIS

TY - JOUR

T1 - Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion

AU - Johansen, A

AU - Nielsen, E-M D

AU - Andersen, G

AU - Hamid, Y H

AU - Jensen, D P

AU - Glümer, C

AU - Drivsholm, T

AU - Borch-Johnsen, K

AU - Jørgensen, T

AU - Hansen, T

AU - Pedersen, O

PY - 2004/8/1

Y1 - 2004/8/1

N2 - Polymorphisms of the butyrylcholinesterase gene (BCHE) are reported to associate with Alzheimer's disease and a recent study found a significant association of the BCHE K variant (G1615A/Ala539Thr) with Type 2 diabetes. The objectives of our study were to examine whether the BCHE K variant is associated with Type 2 diabetes or estimates of pancreatic beta cell function in large-scale populations of glucose-tolerant Caucasians.

AB - Polymorphisms of the butyrylcholinesterase gene (BCHE) are reported to associate with Alzheimer's disease and a recent study found a significant association of the BCHE K variant (G1615A/Ala539Thr) with Type 2 diabetes. The objectives of our study were to examine whether the BCHE K variant is associated with Type 2 diabetes or estimates of pancreatic beta cell function in large-scale populations of glucose-tolerant Caucasians.

KW - Amino Acid Substitution

KW - Base Sequence

KW - Blood Glucose

KW - Butyrylcholinesterase

KW - DNA Primers

KW - Diabetes Mellitus, Type 2

KW - Gene Frequency

KW - Genetic Variation

KW - Genotype

KW - Humans

KW - Insulin

KW - Polymerase Chain Reaction

KW - Polymorphism, Restriction Fragment Length

KW - Polymorphism, Single Nucleotide

KW - Reference Values

U2 - 10.1007/s00125-004-1459-7

DO - 10.1007/s00125-004-1459-7

M3 - Journal article

C2 - 15258737

VL - 47

SP - 1437

EP - 1441

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 8

ER -

ID: 33030584