Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort

Research output: Contribution to journalJournal articlepeer-review

Standard

Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence : The Danish Nurse Cohort. / Lim, Youn-Hee; Jørgensen, Jeanette T; So, Rina; Cole-Hunter, Tom; Mehta, Amar J; Amini, Heresh; Bräuner, Elvira V; Westendorp, Rudi G J; Liu, Shuo; Mortensen, Laust H; Hoffmann, Barbara; Loft, Steffen; Ketzel, Matthias; Hertel, Ole; Brandt, Jørgen; Jensen, Steen Solvang; Backalarz, Claus; Simonsen, Mette K; Tasic, Nebojsa; Maric, Matija; Andersen, Zorana J.

In: Journal of the American Heart Association, Vol. 10, No. 20, e021436, 2021.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Lim, Y-H, Jørgensen, JT, So, R, Cole-Hunter, T, Mehta, AJ, Amini, H, Bräuner, EV, Westendorp, RGJ, Liu, S, Mortensen, LH, Hoffmann, B, Loft, S, Ketzel, M, Hertel, O, Brandt, J, Jensen, SS, Backalarz, C, Simonsen, MK, Tasic, N, Maric, M & Andersen, ZJ 2021, 'Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort', Journal of the American Heart Association, vol. 10, no. 20, e021436. https://doi.org/10.1161/JAHA.121.021436

APA

Lim, Y-H., Jørgensen, J. T., So, R., Cole-Hunter, T., Mehta, A. J., Amini, H., Bräuner, E. V., Westendorp, R. G. J., Liu, S., Mortensen, L. H., Hoffmann, B., Loft, S., Ketzel, M., Hertel, O., Brandt, J., Jensen, S. S., Backalarz, C., Simonsen, M. K., Tasic, N., ... Andersen, Z. J. (2021). Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort. Journal of the American Heart Association, 10(20), [e021436]. https://doi.org/10.1161/JAHA.121.021436

Vancouver

Lim Y-H, Jørgensen JT, So R, Cole-Hunter T, Mehta AJ, Amini H et al. Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort. Journal of the American Heart Association. 2021;10(20). e021436. https://doi.org/10.1161/JAHA.121.021436

Author

Lim, Youn-Hee ; Jørgensen, Jeanette T ; So, Rina ; Cole-Hunter, Tom ; Mehta, Amar J ; Amini, Heresh ; Bräuner, Elvira V ; Westendorp, Rudi G J ; Liu, Shuo ; Mortensen, Laust H ; Hoffmann, Barbara ; Loft, Steffen ; Ketzel, Matthias ; Hertel, Ole ; Brandt, Jørgen ; Jensen, Steen Solvang ; Backalarz, Claus ; Simonsen, Mette K ; Tasic, Nebojsa ; Maric, Matija ; Andersen, Zorana J. / Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence : The Danish Nurse Cohort. In: Journal of the American Heart Association. 2021 ; Vol. 10, No. 20.

Bibtex

@article{dcd67089543a4d77b59d192d36c1495a,
title = "Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort",
abstract = "Background We examined the association of long-term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And Results Using data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3-year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models, adjusting for relevant confounders. Incidence of HF was defined as the first hospital contact (inpatient, outpatient, or emergency) between cohort baseline (1993 or 1999) and December 31, 2014, based on the Danish National Patient Register. Annual mean levels of particulate matter with a diameter <2.5 µm since 1990 and NO2 and road traffic noise since 1970 were estimated at participants' residences. Of the 22 189 nurses, 484 developed HF. We detected associations with all 3 pollutants, with hazard ratios (HRs) of 1.17 (95% CI, 1.01-1.36), 1.10 (95% CI, 0.99-1.22), and 1.12 (95% CI, 0.99-1.26) per increase of 5.1 µg/m3 in particulate matter with a diameter <2.5 µm, 8.6 µg/m3 in NO2, and 9.3 dB in road traffic noise, respectively. We observed an enhanced risk of HF incidence for those exposed to high levels of the 3 pollutants; however, the effect modification of coexposure was not statistically significant. Former smokers and nurses with hypertension showed the strongest associations with particulate matter with a diameter <2.5 µm (Peffect modification<0.05). Conclusions We found that long-term exposures to air pollution and road traffic noise were independently associated with HF.",
author = "Youn-Hee Lim and J{\o}rgensen, {Jeanette T} and Rina So and Tom Cole-Hunter and Mehta, {Amar J} and Heresh Amini and Br{\"a}uner, {Elvira V} and Westendorp, {Rudi G J} and Shuo Liu and Mortensen, {Laust H} and Barbara Hoffmann and Steffen Loft and Matthias Ketzel and Ole Hertel and J{\o}rgen Brandt and Jensen, {Steen Solvang} and Claus Backalarz and Simonsen, {Mette K} and Nebojsa Tasic and Matija Maric and Andersen, {Zorana J}",
year = "2021",
doi = "10.1161/JAHA.121.021436",
language = "English",
volume = "10",
journal = "Journal of the American Heart Association",
issn = "2047-9980",
publisher = "Wiley-Blackwell",
number = "20",

}

RIS

TY - JOUR

T1 - Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence

T2 - The Danish Nurse Cohort

AU - Lim, Youn-Hee

AU - Jørgensen, Jeanette T

AU - So, Rina

AU - Cole-Hunter, Tom

AU - Mehta, Amar J

AU - Amini, Heresh

AU - Bräuner, Elvira V

AU - Westendorp, Rudi G J

AU - Liu, Shuo

AU - Mortensen, Laust H

AU - Hoffmann, Barbara

AU - Loft, Steffen

AU - Ketzel, Matthias

AU - Hertel, Ole

AU - Brandt, Jørgen

AU - Jensen, Steen Solvang

AU - Backalarz, Claus

AU - Simonsen, Mette K

AU - Tasic, Nebojsa

AU - Maric, Matija

AU - Andersen, Zorana J

PY - 2021

Y1 - 2021

N2 - Background We examined the association of long-term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And Results Using data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3-year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models, adjusting for relevant confounders. Incidence of HF was defined as the first hospital contact (inpatient, outpatient, or emergency) between cohort baseline (1993 or 1999) and December 31, 2014, based on the Danish National Patient Register. Annual mean levels of particulate matter with a diameter <2.5 µm since 1990 and NO2 and road traffic noise since 1970 were estimated at participants' residences. Of the 22 189 nurses, 484 developed HF. We detected associations with all 3 pollutants, with hazard ratios (HRs) of 1.17 (95% CI, 1.01-1.36), 1.10 (95% CI, 0.99-1.22), and 1.12 (95% CI, 0.99-1.26) per increase of 5.1 µg/m3 in particulate matter with a diameter <2.5 µm, 8.6 µg/m3 in NO2, and 9.3 dB in road traffic noise, respectively. We observed an enhanced risk of HF incidence for those exposed to high levels of the 3 pollutants; however, the effect modification of coexposure was not statistically significant. Former smokers and nurses with hypertension showed the strongest associations with particulate matter with a diameter <2.5 µm (Peffect modification<0.05). Conclusions We found that long-term exposures to air pollution and road traffic noise were independently associated with HF.

AB - Background We examined the association of long-term exposure to air pollution and road traffic noise with incident heart failure (HF). Methods And Results Using data on female nurses from the Danish Nurse Cohort (aged >44 years), we investigated associations between 3-year mean exposures to air pollution and road traffic noise and incident HF using Cox regression models, adjusting for relevant confounders. Incidence of HF was defined as the first hospital contact (inpatient, outpatient, or emergency) between cohort baseline (1993 or 1999) and December 31, 2014, based on the Danish National Patient Register. Annual mean levels of particulate matter with a diameter <2.5 µm since 1990 and NO2 and road traffic noise since 1970 were estimated at participants' residences. Of the 22 189 nurses, 484 developed HF. We detected associations with all 3 pollutants, with hazard ratios (HRs) of 1.17 (95% CI, 1.01-1.36), 1.10 (95% CI, 0.99-1.22), and 1.12 (95% CI, 0.99-1.26) per increase of 5.1 µg/m3 in particulate matter with a diameter <2.5 µm, 8.6 µg/m3 in NO2, and 9.3 dB in road traffic noise, respectively. We observed an enhanced risk of HF incidence for those exposed to high levels of the 3 pollutants; however, the effect modification of coexposure was not statistically significant. Former smokers and nurses with hypertension showed the strongest associations with particulate matter with a diameter <2.5 µm (Peffect modification<0.05). Conclusions We found that long-term exposures to air pollution and road traffic noise were independently associated with HF.

U2 - 10.1161/JAHA.121.021436

DO - 10.1161/JAHA.121.021436

M3 - Journal article

C2 - 34612059

VL - 10

JO - Journal of the American Heart Association

JF - Journal of the American Heart Association

SN - 2047-9980

IS - 20

M1 - e021436

ER -

ID: 281400051