Low birth weight, adult BMI and inflammation in middle age

Research output: Contribution to journal › Conference article › Research › peer-review

Standard

Low birth weight, adult BMI and inflammation in middle age. / Pedersen, Jolene Lee Masters; Rod, Naja Hulvej; Avlund, Kirsten; Budtz-Jørgensen, Esben; Mortensen, Erik Lykke; Sørensen, Thorkild I.A.; Lund, Rikke.

In: Gerontologist, Vol. 53, No. suppl. 1, 2013, p. 380.

Research output: Contribution to journal › Conference article › Research › peer-review

Harvard

Pedersen, JLM, Rod, NH, Avlund, K, Budtz-Jørgensen, E, Mortensen, EL, Sørensen, TIA & Lund, R 2013, 'Low birth weight, adult BMI and inflammation in middle age', Gerontologist, vol. 53, no. suppl. 1, pp. 380. https://doi.org/10.1093/geront/gnt151

APA

Pedersen, J. L. M., Rod, N. H., Avlund, K., Budtz-Jørgensen, E., Mortensen, E. L., Sørensen, T. I. A., & Lund, R. (2013). Low birth weight, adult BMI and inflammation in middle age. Gerontologist, 53(suppl. 1), 380. https://doi.org/10.1093/geront/gnt151

Vancouver

Pedersen JLM, Rod NH, Avlund K, Budtz-Jørgensen E, Mortensen EL, Sørensen TIA et al. Low birth weight, adult BMI and inflammation in middle age. Gerontologist. 2013;53(suppl. 1):380. https://doi.org/10.1093/geront/gnt151

Author

Pedersen, Jolene Lee Masters ; Rod, Naja Hulvej ; Avlund, Kirsten ; Budtz-Jørgensen, Esben ; Mortensen, Erik Lykke ; Sørensen, Thorkild I.A. ; Lund, Rikke. / Low birth weight, adult BMI and inflammation in middle age. In: Gerontologist. 2013 ; Vol. 53, No. suppl. 1. pp. 380.

Bibtex

@inproceedings{6d987d45f19546b392154afe07a9f587,
title = "Low birth weight, adult BMI and inflammation in middle age",
abstract = "This study examines the association between birthweight and adultBMI with inflammation in middle age measured by interleukin 6 (IL-6), interleukin 10 (IL-10), interleukin 18 (IL-18), high sensitivity Creactiveprotein (hsCRP) and tumor necrosis factor alpha (tnf-α). Thestudy is based on participants with continued participation in the CopenhagenPerinatal cohort and Copenhagen Aging and Midlife Biobankclinical examination (n=1,719). Birthweight was negatively associatedwith hsCRP and IL-18.No association was identified with tnf-α, IL-6and IL-10. Adult BMI was positively and significantly associated withall measures of inflammation besides IL-10. Finally, participants in boththe lowest tertile of birthweight and highest tertile of adult BMI hadthe highest levels of all inflammatory markers. Low birthweight andhigh adult BMI are risk factors for inflammation in middle age. Whilethe prenatal period may be sensitive for development of inflammationit appears that modification by adult BMI occurred in this sample.",
author = "Pedersen, {Jolene Lee Masters} and Rod, {Naja Hulvej} and Kirsten Avlund and Esben Budtz-J{\o}rgensen and Mortensen, {Erik Lykke} and S{\o}rensen, {Thorkild I.A.} and Rikke Lund",
year = "2013",
doi = "10.1093/geront/gnt151",
language = "English",
volume = "53",
pages = "380",
journal = "The Gerontologist",
issn = "0016-9013",
publisher = "Oxford University Press",
number = "suppl. 1",

}

RIS

TY - GEN

T1 - Low birth weight, adult BMI and inflammation in middle age

AU - Pedersen, Jolene Lee Masters

AU - Rod, Naja Hulvej

AU - Avlund, Kirsten

AU - Budtz-Jørgensen, Esben

AU - Mortensen, Erik Lykke

AU - Sørensen, Thorkild I.A.

AU - Lund, Rikke

PY - 2013

Y1 - 2013

N2 - This study examines the association between birthweight and adultBMI with inflammation in middle age measured by interleukin 6 (IL-6), interleukin 10 (IL-10), interleukin 18 (IL-18), high sensitivity Creactiveprotein (hsCRP) and tumor necrosis factor alpha (tnf-α). Thestudy is based on participants with continued participation in the CopenhagenPerinatal cohort and Copenhagen Aging and Midlife Biobankclinical examination (n=1,719). Birthweight was negatively associatedwith hsCRP and IL-18.No association was identified with tnf-α, IL-6and IL-10. Adult BMI was positively and significantly associated withall measures of inflammation besides IL-10. Finally, participants in boththe lowest tertile of birthweight and highest tertile of adult BMI hadthe highest levels of all inflammatory markers. Low birthweight andhigh adult BMI are risk factors for inflammation in middle age. Whilethe prenatal period may be sensitive for development of inflammationit appears that modification by adult BMI occurred in this sample.

AB - This study examines the association between birthweight and adultBMI with inflammation in middle age measured by interleukin 6 (IL-6), interleukin 10 (IL-10), interleukin 18 (IL-18), high sensitivity Creactiveprotein (hsCRP) and tumor necrosis factor alpha (tnf-α). Thestudy is based on participants with continued participation in the CopenhagenPerinatal cohort and Copenhagen Aging and Midlife Biobankclinical examination (n=1,719). Birthweight was negatively associatedwith hsCRP and IL-18.No association was identified with tnf-α, IL-6and IL-10. Adult BMI was positively and significantly associated withall measures of inflammation besides IL-10. Finally, participants in boththe lowest tertile of birthweight and highest tertile of adult BMI hadthe highest levels of all inflammatory markers. Low birthweight andhigh adult BMI are risk factors for inflammation in middle age. Whilethe prenatal period may be sensitive for development of inflammationit appears that modification by adult BMI occurred in this sample.

U2 - 10.1093/geront/gnt151

DO - 10.1093/geront/gnt151

M3 - Conference article

VL - 53

SP - 380

JO - The Gerontologist

JF - The Gerontologist

SN - 0016-9013

IS - suppl. 1

ER -

ID: 118448788