Observations on the periodicity of Plasmodium falciparum gametocytes in natural human infections
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Observations on the periodicity of Plasmodium falciparum gametocytes in natural human infections. / Magesa, S M; Mdira, Y K; Akida, J A; Bygbjerg, I C; Jakobsen, P H.
In: Acta Tropica, Vol. 76, No. 3, 2000, p. 239-46.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Observations on the periodicity of Plasmodium falciparum gametocytes in natural human infections
AU - Magesa, S M
AU - Mdira, Y K
AU - Akida, J A
AU - Bygbjerg, I C
AU - Jakobsen, P H
N1 - Keywords: Animals; Anopheles; Child, Preschool; Female; Humans; Infant; Insect Vectors; Malaria, Falciparum; Male; Mathematics; Microfilaria; Parasitemia; Periodicity; Plasmodium falciparum; Tanzania; Time Factors
PY - 2000
Y1 - 2000
N2 - The circadian periodicity of Plasmodium falciparum gametocytes in peripheral blood was analysed in a group of children from an holoendemic community of north-eastern Tanzania. No periodicity was observed with asexual stage parasites. Gametocytes were shown to display a diurnal subperiodic pattern with a periodicity index of 31. 8. Mathematical analysis of the data indicated that P. falciparum gametocytes tend to display periodicity with a peak (15:30-19:30 h) that do not coincide with the peak (00:30-03:30 h) biting activity of the local vector, Anopheles gambiae. We were thus able to show a P. falciparum gametocyte periodicity with a harmonic wave pattern, but its functional biological significance if any, is currently unknown.
AB - The circadian periodicity of Plasmodium falciparum gametocytes in peripheral blood was analysed in a group of children from an holoendemic community of north-eastern Tanzania. No periodicity was observed with asexual stage parasites. Gametocytes were shown to display a diurnal subperiodic pattern with a periodicity index of 31. 8. Mathematical analysis of the data indicated that P. falciparum gametocytes tend to display periodicity with a peak (15:30-19:30 h) that do not coincide with the peak (00:30-03:30 h) biting activity of the local vector, Anopheles gambiae. We were thus able to show a P. falciparum gametocyte periodicity with a harmonic wave pattern, but its functional biological significance if any, is currently unknown.
M3 - Journal article
C2 - 10974164
VL - 76
SP - 239
EP - 246
JO - Acta Tropica
JF - Acta Tropica
SN - 0001-706X
IS - 3
ER -
ID: 9830464