Occupational variation in incidence of bladder cancer: a comparison of population-representative cohorts from Nordic countries and Canada

Research output: Contribution to journalJournal articleResearchpeer-review

Kishor Hadkhale, Jill MacLeod, Paul A. Demers, Jan Ivar Martinsen, Elisabete Weiderpass, Kristina Kjaerheim, Elsebeth Lynge, Pär Sparen, Laufey Tryggvadottir, M. Anne Harris, Michael Tjepkema, Paul A. Peters, Eero Pukkala

Objectives: The objective of this study was to compare occupational variation of the risk of bladder cancer in the Nordic countries and Canada.

Methods: In the Nordic Occupational Cancer study (NOCCA), 73 653 bladder cancer cases were observed during follow-up of 141.6 million person-years. In the Canadian Census Health and Environment Cohort (CanCHEC), 8170 cases were observed during the follow-up of 36.7 million person-years. Standardised incidence ratios with 95% CI were estimated for 53 occupations in the NOCCA cohort and HR with 95% CIs were estimated for 42 occupations in the CanCHEC.

Results: Elevated risks of bladder cancer were observed among hairdressers, printers, sales workers, plumbers, painters, miners and laundry workers. Teachers and agricultural workers had reduced risk of bladder cancer in both cohorts. Chimney-sweeps, tobacco workers and waiters had about 1.5-fold risk in the Nordic countries; no risk estimates for these categories were given from the CanCHEC cohort.

Conclusion: We observed different occupational patterns in risk of bladder cancer in Nordic countries and Canada. The only occupation with similarly increased risk was observed among sales workers. Differences in smoking across occupational groups may explain some, but not all, of this variation.
Original languageEnglish
Article numbere016538
JournalB M J Open
Volume7
Issue number8
Pages (from-to)1-9
Number of pages9
ISSN2044-6055
DOIs
Publication statusPublished - 1 Aug 2017

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