Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study

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Standard

Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study. / Nielsen, N R; Kristensen, T S; Strandberg-Larsen, Katrine; Zhang, Z-F; Schnohr, P; Grønbaek, M.

In: Journal of Internal Medicine, Vol. 263, No. 2, 2008, p. 192-202.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Nielsen, NR, Kristensen, TS, Strandberg-Larsen, K, Zhang, Z-F, Schnohr, P & Grønbaek, M 2008, 'Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study', Journal of Internal Medicine, vol. 263, no. 2, pp. 192-202. https://doi.org/10.1111/j.1365-2796.2007.01826.x

APA

Nielsen, N. R., Kristensen, T. S., Strandberg-Larsen, K., Zhang, Z-F., Schnohr, P., & Grønbaek, M. (2008). Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study. Journal of Internal Medicine, 263(2), 192-202. https://doi.org/10.1111/j.1365-2796.2007.01826.x

Vancouver

Nielsen NR, Kristensen TS, Strandberg-Larsen K, Zhang Z-F, Schnohr P, Grønbaek M. Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study. Journal of Internal Medicine. 2008;263(2):192-202. https://doi.org/10.1111/j.1365-2796.2007.01826.x

Author

Nielsen, N R ; Kristensen, T S ; Strandberg-Larsen, Katrine ; Zhang, Z-F ; Schnohr, P ; Grønbaek, M. / Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study. In: Journal of Internal Medicine. 2008 ; Vol. 263, No. 2. pp. 192-202.

Bibtex

@article{4881ef40de3911ddb5fc000ea68e967b,
title = "Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study",
abstract = "OBJECTIVE: We aim to assess the relationship between stress and risk of primary colorectal cancer in men and women. DESIGN: A prospective cohort study. SETTING: The Copenhagen City Heart Study, Denmark. SUBJECTS: A total of 6488 women and 5426 men were included in the study. The participants were asked about intensity and frequency of stress at baseline in 1981-1983 and were followed until the end of 2000 in the Danish Cancer Registry. Less than 0.1{\%} was lost to follow-up. MAIN OUTCOME MEASURES: First time incidence of primary colorectal cancer. RESULTS: During follow-up 162 women and 166 men were diagnosed with colorectal cancer. Women with moderate and high stress intensity had a hazard ratio of 0.60 (95{\%} CI: 0.37-0.98) and 0.52 (0.23-1.14) for colorectal cancer, respectively, compared to women with no stress. For colon cancer, a one-unit increase on a seven-point stress-score was associated with an 11{\%} lower incidence of the disease (HR = 0.89, 95{\%} CI: 0.81-0.99) amongst women. There was no consistent evidence of an association between stress and colorectal cancer in men. CONCLUSION: Perceived stress was associated with lower risk of particularly colon cancer in women, whilst there was no clear relationship between stress and colorectal cancer in men.",
author = "Nielsen, {N R} and Kristensen, {T S} and Katrine Strandberg-Larsen and Z-F Zhang and P Schnohr and M Gr{\o}nbaek",
note = "Keywords: Adult; Aged; Aged, 80 and over; Cohort Studies; Colorectal Neoplasms; Denmark; Female; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stress, Psychological",
year = "2008",
doi = "10.1111/j.1365-2796.2007.01826.x",
language = "English",
volume = "263",
pages = "192--202",
journal = "Acta Medica Scandinavica",
issn = "0955-7873",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Perceived stress and risk of colorectal cancer in men and women: a prospective cohort study

AU - Nielsen, N R

AU - Kristensen, T S

AU - Strandberg-Larsen, Katrine

AU - Zhang, Z-F

AU - Schnohr, P

AU - Grønbaek, M

N1 - Keywords: Adult; Aged; Aged, 80 and over; Cohort Studies; Colorectal Neoplasms; Denmark; Female; Humans; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stress, Psychological

PY - 2008

Y1 - 2008

N2 - OBJECTIVE: We aim to assess the relationship between stress and risk of primary colorectal cancer in men and women. DESIGN: A prospective cohort study. SETTING: The Copenhagen City Heart Study, Denmark. SUBJECTS: A total of 6488 women and 5426 men were included in the study. The participants were asked about intensity and frequency of stress at baseline in 1981-1983 and were followed until the end of 2000 in the Danish Cancer Registry. Less than 0.1% was lost to follow-up. MAIN OUTCOME MEASURES: First time incidence of primary colorectal cancer. RESULTS: During follow-up 162 women and 166 men were diagnosed with colorectal cancer. Women with moderate and high stress intensity had a hazard ratio of 0.60 (95% CI: 0.37-0.98) and 0.52 (0.23-1.14) for colorectal cancer, respectively, compared to women with no stress. For colon cancer, a one-unit increase on a seven-point stress-score was associated with an 11% lower incidence of the disease (HR = 0.89, 95% CI: 0.81-0.99) amongst women. There was no consistent evidence of an association between stress and colorectal cancer in men. CONCLUSION: Perceived stress was associated with lower risk of particularly colon cancer in women, whilst there was no clear relationship between stress and colorectal cancer in men.

AB - OBJECTIVE: We aim to assess the relationship between stress and risk of primary colorectal cancer in men and women. DESIGN: A prospective cohort study. SETTING: The Copenhagen City Heart Study, Denmark. SUBJECTS: A total of 6488 women and 5426 men were included in the study. The participants were asked about intensity and frequency of stress at baseline in 1981-1983 and were followed until the end of 2000 in the Danish Cancer Registry. Less than 0.1% was lost to follow-up. MAIN OUTCOME MEASURES: First time incidence of primary colorectal cancer. RESULTS: During follow-up 162 women and 166 men were diagnosed with colorectal cancer. Women with moderate and high stress intensity had a hazard ratio of 0.60 (95% CI: 0.37-0.98) and 0.52 (0.23-1.14) for colorectal cancer, respectively, compared to women with no stress. For colon cancer, a one-unit increase on a seven-point stress-score was associated with an 11% lower incidence of the disease (HR = 0.89, 95% CI: 0.81-0.99) amongst women. There was no consistent evidence of an association between stress and colorectal cancer in men. CONCLUSION: Perceived stress was associated with lower risk of particularly colon cancer in women, whilst there was no clear relationship between stress and colorectal cancer in men.

U2 - 10.1111/j.1365-2796.2007.01826.x

DO - 10.1111/j.1365-2796.2007.01826.x

M3 - Journal article

C2 - 18226096

VL - 263

SP - 192

EP - 202

JO - Acta Medica Scandinavica

JF - Acta Medica Scandinavica

SN - 0955-7873

IS - 2

ER -

ID: 9612731