Personality and risk of hospital diagnosed mental disorder: a 35 years’ prospective study
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Personality and risk of hospital diagnosed mental disorder : a 35 years’ prospective study. / Christensen, D. S.; Flensborg-Madsen, T.; Andersen, N. E.; Rosenkær, I. B.; Mortensen, E. L.
In: Social Psychiatry and Psychiatric Epidemiology, Vol. 56, 2021, p. 2073–2081.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Personality and risk of hospital diagnosed mental disorder
T2 - a 35 years’ prospective study
AU - Christensen, D. S.
AU - Flensborg-Madsen, T.
AU - Andersen, N. E.
AU - Rosenkær, I. B.
AU - Mortensen, E. L.
PY - 2021
Y1 - 2021
N2 - Purpose: The present study examined the prospective association of neuroticism, extraversion and psychoticism with risk of hospital diagnosed mental disorder, examining intelligence as a potential confounder of this association. Methods: A total of 1118 Danish men and women completed the Eysenck personality questionnaire at the mean age of 27 years. Information on psychiatric diagnoses was obtained by linking the study population to the national Danish psychiatric registers, and risk of diagnoses associated with each personality trait was examined using multiple Cox regression in models including the three personality traits unadjusted and adjusted for intelligence. Participants with diagnosis from a psychiatric department prior to the personality assessment were excluded. Results: In total, 122 participants were diagnosed with a mental disorder during follow-up. Neuroticism significantly predicted risk of anxiety-, adjustment-, personality- and alcohol and substance abuse diagnoses. Extraversion did not significantly predict any diagnosis type, while psychoticism predicted a combined category of mood and anxiety diagnoses. Despite intelligence being a significant predictor of the majority of the included diagnoses, adjusting for intelligence did not substantially influence any trait-disorder associations. Conclusion: The results confirm high neuroticism as a prospective vulnerability factor for mental disorder and indicate high psychoticism to be a potential risk factor for mood and anxiety disorders. These associations are not confounded by intelligence.
AB - Purpose: The present study examined the prospective association of neuroticism, extraversion and psychoticism with risk of hospital diagnosed mental disorder, examining intelligence as a potential confounder of this association. Methods: A total of 1118 Danish men and women completed the Eysenck personality questionnaire at the mean age of 27 years. Information on psychiatric diagnoses was obtained by linking the study population to the national Danish psychiatric registers, and risk of diagnoses associated with each personality trait was examined using multiple Cox regression in models including the three personality traits unadjusted and adjusted for intelligence. Participants with diagnosis from a psychiatric department prior to the personality assessment were excluded. Results: In total, 122 participants were diagnosed with a mental disorder during follow-up. Neuroticism significantly predicted risk of anxiety-, adjustment-, personality- and alcohol and substance abuse diagnoses. Extraversion did not significantly predict any diagnosis type, while psychoticism predicted a combined category of mood and anxiety diagnoses. Despite intelligence being a significant predictor of the majority of the included diagnoses, adjusting for intelligence did not substantially influence any trait-disorder associations. Conclusion: The results confirm high neuroticism as a prospective vulnerability factor for mental disorder and indicate high psychoticism to be a potential risk factor for mood and anxiety disorders. These associations are not confounded by intelligence.
KW - Intelligence
KW - Mental disorder
KW - Personality
KW - Prospective cohort study
U2 - 10.1007/s00127-020-02001-9
DO - 10.1007/s00127-020-02001-9
M3 - Journal article
C2 - 33388796
AN - SCOPUS:85098640581
VL - 56
SP - 2073
EP - 2081
JO - Social Psychiatry and Psychiatric Epidemiology
JF - Social Psychiatry and Psychiatric Epidemiology
SN - 0933-7954
ER -
ID: 254990813