Pregnancy, cardiovascular health, and microchimerism

Department of Public Health

Pregnancy, cardiovascular health, and microchimerism

Research output: Contribution to journal › Review › Research › peer-review

Standard

Pregnancy, cardiovascular health, and microchimerism. / Søndergaard, Sara Hallum; Kamper-Jørgensen, Mads.

In: Current Opinion in Lipidology, Vol. 35, No. 1, 2024, p. 7-13.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Søndergaard, SH & Kamper-Jørgensen, M 2024, 'Pregnancy, cardiovascular health, and microchimerism', Current Opinion in Lipidology, vol. 35, no. 1, pp. 7-13. https://doi.org/10.1097/MOL.0000000000000914

APA

Søndergaard, S. H., & Kamper-Jørgensen, M. (2024). Pregnancy, cardiovascular health, and microchimerism. Current Opinion in Lipidology, 35(1), 7-13. https://doi.org/10.1097/MOL.0000000000000914

Vancouver

Søndergaard SH, Kamper-Jørgensen M. Pregnancy, cardiovascular health, and microchimerism. Current Opinion in Lipidology. 2024;35(1):7-13. https://doi.org/10.1097/MOL.0000000000000914

Author

Søndergaard, Sara Hallum ; Kamper-Jørgensen, Mads. / Pregnancy, cardiovascular health, and microchimerism. In: Current Opinion in Lipidology. 2024 ; Vol. 35, No. 1. pp. 7-13.

Bibtex

@article{ce4687df05ce4fda94bc27db8dcf272f,

title = "Pregnancy, cardiovascular health, and microchimerism",

abstract = "Purpose of reviewTo provide an updated review of scientific literature concerning associations between pregnancy and cardiovascular health among women, and to discuss a possible impact of microchimerism on the association.Recent findingsIn most studies, pregnancy and childbirth is associated with increased risk of cardiovascular disease in women. Some ascribe the association mainly to lifestyle, whereas others suggest that pregnancy itself negatively affects women's cardiovascular health. Pregnancy is a natural source of microchimerism, which in turn markedly affects female health. The only study published in the area surprisingly shows that among middle-aged women, male-origin microchimerism (MOM) is associated with half the risk of developing ischemic heart disease (IHD). No similar association is found between MOM and ischemic stroke.SummaryThe sparse evidence published suggests reduced risk of developing IHD among MOM-positive women. Despite the association being biologically plausible, replication of the findings is warranted to support that this is not a chance finding.",

keywords = "cardiovascular disease, microchimerism, pregnancy, review",

author = "S{\o}ndergaard, {Sara Hallum} and Mads Kamper-J{\o}rgensen",

year = "2024",

doi = "10.1097/MOL.0000000000000914",

language = "English",

volume = "35",

pages = "7--13",

journal = "Current Opinion in Lipidology",

issn = "0957-9672",

publisher = "Lippincott Williams & Wilkins, Ltd.",

number = "1",

}

RIS

TY - JOUR

T1 - Pregnancy, cardiovascular health, and microchimerism

AU - Søndergaard, Sara Hallum

AU - Kamper-Jørgensen, Mads

PY - 2024

Y1 - 2024

N2 - Purpose of reviewTo provide an updated review of scientific literature concerning associations between pregnancy and cardiovascular health among women, and to discuss a possible impact of microchimerism on the association.Recent findingsIn most studies, pregnancy and childbirth is associated with increased risk of cardiovascular disease in women. Some ascribe the association mainly to lifestyle, whereas others suggest that pregnancy itself negatively affects women's cardiovascular health. Pregnancy is a natural source of microchimerism, which in turn markedly affects female health. The only study published in the area surprisingly shows that among middle-aged women, male-origin microchimerism (MOM) is associated with half the risk of developing ischemic heart disease (IHD). No similar association is found between MOM and ischemic stroke.SummaryThe sparse evidence published suggests reduced risk of developing IHD among MOM-positive women. Despite the association being biologically plausible, replication of the findings is warranted to support that this is not a chance finding.

AB - Purpose of reviewTo provide an updated review of scientific literature concerning associations between pregnancy and cardiovascular health among women, and to discuss a possible impact of microchimerism on the association.Recent findingsIn most studies, pregnancy and childbirth is associated with increased risk of cardiovascular disease in women. Some ascribe the association mainly to lifestyle, whereas others suggest that pregnancy itself negatively affects women's cardiovascular health. Pregnancy is a natural source of microchimerism, which in turn markedly affects female health. The only study published in the area surprisingly shows that among middle-aged women, male-origin microchimerism (MOM) is associated with half the risk of developing ischemic heart disease (IHD). No similar association is found between MOM and ischemic stroke.SummaryThe sparse evidence published suggests reduced risk of developing IHD among MOM-positive women. Despite the association being biologically plausible, replication of the findings is warranted to support that this is not a chance finding.

KW - cardiovascular disease

KW - microchimerism

KW - pregnancy

KW - review

U2 - 10.1097/MOL.0000000000000914

DO - 10.1097/MOL.0000000000000914

M3 - Review

C2 - 37982290

AN - SCOPUS:85180331185

VL - 35

SP - 7

EP - 13

JO - Current Opinion in Lipidology

JF - Current Opinion in Lipidology

SN - 0957-9672

IS - 1

ER -

ID: 382332463