Primary prevention of fat and weight gain among obesity susceptible healthy weight preschool children: Main results from the “Healthy Start” randomized controlled intervention
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Primary prevention of fat and weight gain among obesity susceptible healthy weight preschool children : Main results from the “Healthy Start” randomized controlled intervention. / Olsen, Nanna Julie; Ängquist, Lars; Frederiksen, Peder; Lykke Mortensen, Erik; Lilienthal Heitmann, Berit.
In: Pediatric Obesity, Vol. 16, No. 4, e12736, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Primary prevention of fat and weight gain among obesity susceptible healthy weight preschool children
T2 - Main results from the “Healthy Start” randomized controlled intervention
AU - Olsen, Nanna Julie
AU - Ängquist, Lars
AU - Frederiksen, Peder
AU - Lykke Mortensen, Erik
AU - Lilienthal Heitmann, Berit
PY - 2021
Y1 - 2021
N2 - Background: A vital public health challenge lies in understanding the primary drivers behind excessive weight gain among healthy weight individuals. Objectives: To examine if excessive weight and fat gain can be prevented among healthy weight, obesity susceptible children aged 2 to 6 years. Methods: Eligible children were identified based on information on either a high birth weight, maternal pre-pregnancy obesity or maternal low educational level from national registries, and randomized into an intervention group, a control group and a shadow control group. All children with overweight at baseline were excluded from subsequent analysis (n = 196), while healthy weight children were included (n = 926). The intervention was designed to deliver improvements in diet and physical activity habits, optimization of sleep quantity and quality, and reduction of family stress. The average intervention period was 1.3 years. Results: Intention-to-treat analyses indicated a lower gain in percentage fat mass and a higher gain in fat-free mass in the intervention group compared with the control group. However, the results should be interpreted with caution, as they were clinically small and borderline significant, only. Conclusion: This primary prevention intervention among young healthy weight children with susceptibility to future obesity had clinically small effects on growth and body composition. More interventions, conducting primary obesity prevention, are urgently needed.
AB - Background: A vital public health challenge lies in understanding the primary drivers behind excessive weight gain among healthy weight individuals. Objectives: To examine if excessive weight and fat gain can be prevented among healthy weight, obesity susceptible children aged 2 to 6 years. Methods: Eligible children were identified based on information on either a high birth weight, maternal pre-pregnancy obesity or maternal low educational level from national registries, and randomized into an intervention group, a control group and a shadow control group. All children with overweight at baseline were excluded from subsequent analysis (n = 196), while healthy weight children were included (n = 926). The intervention was designed to deliver improvements in diet and physical activity habits, optimization of sleep quantity and quality, and reduction of family stress. The average intervention period was 1.3 years. Results: Intention-to-treat analyses indicated a lower gain in percentage fat mass and a higher gain in fat-free mass in the intervention group compared with the control group. However, the results should be interpreted with caution, as they were clinically small and borderline significant, only. Conclusion: This primary prevention intervention among young healthy weight children with susceptibility to future obesity had clinically small effects on growth and body composition. More interventions, conducting primary obesity prevention, are urgently needed.
KW - children
KW - intervention
KW - obesity
KW - primary prevention
KW - susceptibility
U2 - 10.1111/ijpo.12736
DO - 10.1111/ijpo.12736
M3 - Journal article
C2 - 33021348
AN - SCOPUS:85092106275
VL - 16
JO - Pediatric obesity
JF - Pediatric obesity
SN - 2047-6302
IS - 4
M1 - e12736
ER -
ID: 249856420