TY - JOUR

T1 - Radiologic assessment of bone maturity and cortical thickness in experimental osteo-fluorosis in the young pig

AU - Wenzel, A

AU - Kragstrup, J

AU - Richards, A

PY - 1984

Y1 - 1984

N2 - Radiographs of the left forelimb were obtained after slaughter in 16 14-month-old pigs. From age 8-14 months, eight pigs in the experimental group received 2 mg F-/kg body weight per day. Bone maturity in F-animals was the same as in controls. Cortical thickness was increased by 10 per cent in the fluorotic animals (p less than 0.01) and their plasma-fluoride levels increased throughout the experimental period to approximate those reported for man in endemic fluorosis areas. Thus fluoride given in the dose used and over that period, did not affect maturation in the long bones but increased cortical bone mass in the diaphyses.

AB - Radiographs of the left forelimb were obtained after slaughter in 16 14-month-old pigs. From age 8-14 months, eight pigs in the experimental group received 2 mg F-/kg body weight per day. Bone maturity in F-animals was the same as in controls. Cortical thickness was increased by 10 per cent in the fluorotic animals (p less than 0.01) and their plasma-fluoride levels increased throughout the experimental period to approximate those reported for man in endemic fluorosis areas. Thus fluoride given in the dose used and over that period, did not affect maturation in the long bones but increased cortical bone mass in the diaphyses.

KW - Animals

KW - Bone Development/drug effects

KW - Bone and Bones/analysis

KW - Female

KW - Forelimb/diagnostic imaging

KW - Metacarpus/diagnostic imaging

KW - Radiography

KW - Sodium Fluoride/analysis

KW - Swine

U2 - 10.1016/0003-9969(84)90001-3

DO - 10.1016/0003-9969(84)90001-3

M3 - Journal article

C2 - 6594085

VL - 29

SP - 745

EP - 749

JO - Archives of Oral Biology

JF - Archives of Oral Biology

SN - 0003-9969

IS - 10

ER -