Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis. / Diederichsen, H Z; Skamling, M; Diederichsen, A; Grinsted, P; Antonsen, S; Petersen, P H; Munck, A P; Kragstrup, J.

In: Ugeskrift for Laeger, Vol. 163, No. 27, 02.07.2001, p. 3784-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Diederichsen, HZ, Skamling, M, Diederichsen, A, Grinsted, P, Antonsen, S, Petersen, PH, Munck, AP & Kragstrup, J 2001, 'Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis', Ugeskrift for Laeger, vol. 163, no. 27, pp. 3784-7.

APA

Diederichsen, H. Z., Skamling, M., Diederichsen, A., Grinsted, P., Antonsen, S., Petersen, P. H., Munck, A. P., & Kragstrup, J. (2001). Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis. Ugeskrift for Laeger, 163(27), 3784-7.

Vancouver

Diederichsen HZ, Skamling M, Diederichsen A, Grinsted P, Antonsen S, Petersen PH et al. Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis. Ugeskrift for Laeger. 2001 Jul 2;163(27):3784-7.

Author

Diederichsen, H Z ; Skamling, M ; Diederichsen, A ; Grinsted, P ; Antonsen, S ; Petersen, P H ; Munck, A P ; Kragstrup, J. / Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis. In: Ugeskrift for Laeger. 2001 ; Vol. 163, No. 27. pp. 3784-7.

Bibtex

@article{589d225a84a545e8820a0e0e46417944,
title = "Randomiseret, kontrolleret unders{\o}gelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis",
abstract = "INTRODUCTION: The aim was to assess whether the frequency of antibiotic prescriptions to patients with respiratory infections is reduced when general practitioners (GPs) use a CRP rapid test to support their clinical assessment, and to examine whether the use of the test would have any effect on the course of disease.MATERIAL AND METHOD: A randomised controlled trial was carried out by 35 general practices in the County of Funen, Denmark, with 812 patients with respiratory infection. The main outcome measures were frequency of antibiotic prescriptions and morbidity one week after the consultation, as stated by the patients.RESULTS: The frequency of antibiotic prescriptions was 43% (179/414) in the CRP group and 46% (184/398) in the control group (NS, OR = 0.9). At one week, increased or unchanged morbidity was stated more frequently in the CRP group (12%) than in the control group (8%) (OR = 1.6, p = 0.05). In the control group, the variable having the greatest influence on whether the GP prescribed antibiotics was the patient's general well-being (OR = 2.9, p < 0.0001), whereas in the CRP group the CRP value had the greatest influence (OR = 1.1 per unit increase [mg/l], p < 0.0001).CONCLUSION: From on the present study, the use of a single CRP rapid test to support possible antibiotic treatment of respiratory infections in general practice cannot be recommended.",
keywords = "Anti-Bacterial Agents/administration & dosage, Biomarkers/blood, C-Reactive Protein/metabolism, Decision Support Techniques, Denmark, Drug Utilization/statistics & numerical data, Family Practice, Humans, Practice Guidelines as Topic, Practice Patterns, Physicians', Respiratory Tract Infections/blood",
author = "Diederichsen, {H Z} and M Skamling and A Diederichsen and P Grinsted and S Antonsen and Petersen, {P H} and Munck, {A P} and J Kragstrup",
year = "2001",
month = jul,
day = "2",
language = "Dansk",
volume = "163",
pages = "3784--7",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "27",

}

RIS

TY - JOUR

T1 - Randomiseret, kontrolleret undersøgelse af anvendelsen af CRP-hurtigtest som vejledning ved behandlingen af luftvejsinfektioner i almen praksis

AU - Diederichsen, H Z

AU - Skamling, M

AU - Diederichsen, A

AU - Grinsted, P

AU - Antonsen, S

AU - Petersen, P H

AU - Munck, A P

AU - Kragstrup, J

PY - 2001/7/2

Y1 - 2001/7/2

N2 - INTRODUCTION: The aim was to assess whether the frequency of antibiotic prescriptions to patients with respiratory infections is reduced when general practitioners (GPs) use a CRP rapid test to support their clinical assessment, and to examine whether the use of the test would have any effect on the course of disease.MATERIAL AND METHOD: A randomised controlled trial was carried out by 35 general practices in the County of Funen, Denmark, with 812 patients with respiratory infection. The main outcome measures were frequency of antibiotic prescriptions and morbidity one week after the consultation, as stated by the patients.RESULTS: The frequency of antibiotic prescriptions was 43% (179/414) in the CRP group and 46% (184/398) in the control group (NS, OR = 0.9). At one week, increased or unchanged morbidity was stated more frequently in the CRP group (12%) than in the control group (8%) (OR = 1.6, p = 0.05). In the control group, the variable having the greatest influence on whether the GP prescribed antibiotics was the patient's general well-being (OR = 2.9, p < 0.0001), whereas in the CRP group the CRP value had the greatest influence (OR = 1.1 per unit increase [mg/l], p < 0.0001).CONCLUSION: From on the present study, the use of a single CRP rapid test to support possible antibiotic treatment of respiratory infections in general practice cannot be recommended.

AB - INTRODUCTION: The aim was to assess whether the frequency of antibiotic prescriptions to patients with respiratory infections is reduced when general practitioners (GPs) use a CRP rapid test to support their clinical assessment, and to examine whether the use of the test would have any effect on the course of disease.MATERIAL AND METHOD: A randomised controlled trial was carried out by 35 general practices in the County of Funen, Denmark, with 812 patients with respiratory infection. The main outcome measures were frequency of antibiotic prescriptions and morbidity one week after the consultation, as stated by the patients.RESULTS: The frequency of antibiotic prescriptions was 43% (179/414) in the CRP group and 46% (184/398) in the control group (NS, OR = 0.9). At one week, increased or unchanged morbidity was stated more frequently in the CRP group (12%) than in the control group (8%) (OR = 1.6, p = 0.05). In the control group, the variable having the greatest influence on whether the GP prescribed antibiotics was the patient's general well-being (OR = 2.9, p < 0.0001), whereas in the CRP group the CRP value had the greatest influence (OR = 1.1 per unit increase [mg/l], p < 0.0001).CONCLUSION: From on the present study, the use of a single CRP rapid test to support possible antibiotic treatment of respiratory infections in general practice cannot be recommended.

KW - Anti-Bacterial Agents/administration & dosage

KW - Biomarkers/blood

KW - C-Reactive Protein/metabolism

KW - Decision Support Techniques

KW - Denmark

KW - Drug Utilization/statistics & numerical data

KW - Family Practice

KW - Humans

KW - Practice Guidelines as Topic

KW - Practice Patterns, Physicians'

KW - Respiratory Tract Infections/blood

M3 - Tidsskriftartikel

C2 - 11466986

VL - 163

SP - 3784

EP - 3787

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 27

ER -

ID: 324191490