The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects

Research output: Contribution to journalJournal articleResearchpeer-review

  • K Yanagisawa
  • Lesli Hingstrup Larsen
  • G Andersen
  • Drivsholm, Thomas
  • A Cederberg
  • R Westergren
  • K Borch-Johnsen
  • O Pedersen
  • S Enerbäck
  • T Hansen
The transcription factor FOXC2 plays a key role in adipocyte differentiation and the FOXC2 gene is a candidate gene for Type 2 diabetes, obesity and dyslipidaemia. We investigated whether the FOXC2 -512C>T promoter variant is associated with Type 2 diabetes or its intermediary phenotypes in glucose tolerant subjects.
Original languageEnglish
JournalDiabetologia
Volume46
Issue number11
Pages (from-to)1576-1580
Number of pages5
ISSN0012-186X
DOIs
Publication statusPublished - 1 Nov 2003

    Research areas

  • Base Sequence, Body Constitution, C-Peptide, DNA Primers, DNA-Binding Proteins, Denmark, Diabetes Mellitus, European Continental Ancestry Group, Female, Forkhead Transcription Factors, Genetic Variation, Glucose Tolerance Test, Humans, Male, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Reference Values, Sequence Deletion, Transcription Factors

ID: 33030715