The Mothers, Infants, and Lactation Quality (MILQ) Study: A multi-center collaboration
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The Mothers, Infants, and Lactation Quality (MILQ) Study: A multi-center collaboration. / Allen, Lindsay H; Hampel, Daniela; Shahab-Ferdows, Setareh; Andersson, Maria; Barros, Erica; Doel, Andrew M; Eriksen, Kamilla Gehrt; Christensen, Sophie Hilario; Islam, Munirul; Kac, Gilberto; Keya, Farhana Khanam; Michaelsen, Kim F.; de Barros Mucci, Daniela; Njie, Fanta; Peerson, Janet M; Moore, Sophie E.
In: Current Developments in Nutrition, Vol. 5, No. 10, nzab116, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The Mothers, Infants, and Lactation Quality (MILQ) Study: A multi-center collaboration
AU - Allen, Lindsay H
AU - Hampel, Daniela
AU - Shahab-Ferdows, Setareh
AU - Andersson, Maria
AU - Barros, Erica
AU - Doel, Andrew M
AU - Eriksen, Kamilla Gehrt
AU - Christensen, Sophie Hilario
AU - Islam, Munirul
AU - Kac, Gilberto
AU - Keya, Farhana Khanam
AU - Michaelsen, Kim F.
AU - de Barros Mucci, Daniela
AU - Njie, Fanta
AU - Peerson, Janet M
AU - Moore, Sophie E
N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
PY - 2021
Y1 - 2021
N2 - Little valid information is available on human milk nutrient concentrations, especially for micronutrients (MNs), and there are no valid reference values (RVs) across lactation. In this multi-center collaborative study, RVs will be established for human milk nutrients across the first 8.5 mo postpartum. Well-nourished, unsupplemented women in Bangladesh, Brazil, Denmark, and The Gambia (n = 250/site) were recruited during the third trimester of pregnancy. Milk, blood, saliva, urine, and stool samples from mothers and their infants are collected identically at 3 visits (1-3.49, 3.5-5.99, 6.0-8.49 mo postpartum). Milk analyses include macronutrients, selected vitamins, trace elements and minerals, iodine, metabolomics, amino acids, human milk oligosaccharides, and bioactive peptides. We measure milk volume; maternal and infant diets, anthropometry, and morbidity; infant development, maternal genome, and the infant and maternal microbiome. RVs will be constructed based on methods for the WHO Child Growth Standards and the Intergrowth-21st Project. This trial was registered at clinical trials.gov as NCT03254329.
AB - Little valid information is available on human milk nutrient concentrations, especially for micronutrients (MNs), and there are no valid reference values (RVs) across lactation. In this multi-center collaborative study, RVs will be established for human milk nutrients across the first 8.5 mo postpartum. Well-nourished, unsupplemented women in Bangladesh, Brazil, Denmark, and The Gambia (n = 250/site) were recruited during the third trimester of pregnancy. Milk, blood, saliva, urine, and stool samples from mothers and their infants are collected identically at 3 visits (1-3.49, 3.5-5.99, 6.0-8.49 mo postpartum). Milk analyses include macronutrients, selected vitamins, trace elements and minerals, iodine, metabolomics, amino acids, human milk oligosaccharides, and bioactive peptides. We measure milk volume; maternal and infant diets, anthropometry, and morbidity; infant development, maternal genome, and the infant and maternal microbiome. RVs will be constructed based on methods for the WHO Child Growth Standards and the Intergrowth-21st Project. This trial was registered at clinical trials.gov as NCT03254329.
KW - Faculty of Science
KW - Human milk
KW - Macronutrients
KW - Micronutrients
KW - Composistion
KW - Reference values
U2 - 10.1093/cdn/nzab116
DO - 10.1093/cdn/nzab116
M3 - Journal article
C2 - 34712893
VL - 5
JO - Current Developments in Nutrition
JF - Current Developments in Nutrition
SN - 2475-2991
IS - 10
M1 - nzab116
ER -
ID: 282937793