Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts. / Lund-Blix, Nicolai A.; Sander, Stine Dydensborg; Størdal, Ketil; Nybo Andersen, Anne-Marie; Rønningen, Kjersti S.; Joner, Geir; Skrivarhaug, Torild; Njølstad, Pal R.; Husby, Steffen; Stene, Lars C.

In: Diabetes Care, Vol. 40, No. 7, 07.2017, p. 920-927.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Lund-Blix, NA, Sander, SD, Størdal, K, Nybo Andersen, A-M, Rønningen, KS, Joner, G, Skrivarhaug, T, Njølstad, PR, Husby, S & Stene, LC 2017, 'Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts', Diabetes Care, vol. 40, no. 7, pp. 920-927. https://doi.org/10.2337/dc17-0016

APA

Lund-Blix, N. A., Sander, S. D., Størdal, K., Nybo Andersen, A-M., Rønningen, K. S., Joner, G., ... Stene, L. C. (2017). Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts. Diabetes Care, 40(7), 920-927. https://doi.org/10.2337/dc17-0016

Vancouver

Lund-Blix NA, Sander SD, Størdal K, Nybo Andersen A-M, Rønningen KS, Joner G et al. Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts. Diabetes Care. 2017 Jul;40(7):920-927. https://doi.org/10.2337/dc17-0016

Author

Lund-Blix, Nicolai A. ; Sander, Stine Dydensborg ; Størdal, Ketil ; Nybo Andersen, Anne-Marie ; Rønningen, Kjersti S. ; Joner, Geir ; Skrivarhaug, Torild ; Njølstad, Pal R. ; Husby, Steffen ; Stene, Lars C. / Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts. In: Diabetes Care. 2017 ; Vol. 40, No. 7. pp. 920-927.

Bibtex

@article{1152e03716684961b6045232b8174670,
title = "Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts",
abstract = "OBJECTIVE: Our aim was to study the relation between the duration of full and any breastfeeding and risk of type 1 diabetes.RESEARCH DESIGN AND METHODS: We included two population-based cohorts of children followed from birth (1996–2009) to 2014 (Denmark) or 2015 (Norway). We analyzed data from a total of 155,392 children participating in the Norwegian Mother and Child Cohort Study (MoBa) and the Danish National Birth Cohort (DNBC). Parents reported infant dietary practices when their child was 6 and 18 months old. The outcome was clinical type 1 diabetes, ascertained from nationwide childhood diabetes registries. Hazard ratios (HRs) were estimated using Cox regression.RESULTS: Type 1 diabetes was identified in 504 children during follow-up, and the incidence of type 1 diabetes per 100,000 person-years was 30.5 in the Norwegian cohort and 23.5 in the Danish cohort. Children who were never breastfed had a twofold increased risk of type 1 diabetes compared with those who were breastfed (HR 2.29 [95{\%} CI 1.14–4.61] for no breastfeeding vs. any breastfeeding for ≥12 months). Among those who were breastfed, however, the incidence of type 1 diabetes was independent of duration of both full breastfeeding (HR per month 0.99 [95{\%} CI 0.97–1.01]) and any breastfeeding (0.97 [0.92–1.03]).CONCLUSIONS: Suggestive evidence supports the contention that breastfeeding reduces the risk of type 1 diabetes. Among those who were breastfed, however, no evidence indicated that prolonging full or any breastfeeding was associated with a reduced risk of type 1 diabetes.",
author = "Lund-Blix, {Nicolai A.} and Sander, {Stine Dydensborg} and Ketil St{\o}rdal and {Nybo Andersen}, Anne-Marie and R{\o}nningen, {Kjersti S.} and Geir Joner and Torild Skrivarhaug and Nj{\o}lstad, {Pal R.} and Steffen Husby and Stene, {Lars C.}",
year = "2017",
month = "7",
doi = "10.2337/dc17-0016",
language = "English",
volume = "40",
pages = "920--927",
journal = "Diabetes Care",
issn = "0149-5992",
publisher = "American Diabetes Association",
number = "7",

}

RIS

TY - JOUR

T1 - Infant Feeding and Risk of Type 1 Diabetes in Two Large Scandinavian Birth Cohorts

AU - Lund-Blix, Nicolai A.

AU - Sander, Stine Dydensborg

AU - Størdal, Ketil

AU - Nybo Andersen, Anne-Marie

AU - Rønningen, Kjersti S.

AU - Joner, Geir

AU - Skrivarhaug, Torild

AU - Njølstad, Pal R.

AU - Husby, Steffen

AU - Stene, Lars C.

PY - 2017/7

Y1 - 2017/7

N2 - OBJECTIVE: Our aim was to study the relation between the duration of full and any breastfeeding and risk of type 1 diabetes.RESEARCH DESIGN AND METHODS: We included two population-based cohorts of children followed from birth (1996–2009) to 2014 (Denmark) or 2015 (Norway). We analyzed data from a total of 155,392 children participating in the Norwegian Mother and Child Cohort Study (MoBa) and the Danish National Birth Cohort (DNBC). Parents reported infant dietary practices when their child was 6 and 18 months old. The outcome was clinical type 1 diabetes, ascertained from nationwide childhood diabetes registries. Hazard ratios (HRs) were estimated using Cox regression.RESULTS: Type 1 diabetes was identified in 504 children during follow-up, and the incidence of type 1 diabetes per 100,000 person-years was 30.5 in the Norwegian cohort and 23.5 in the Danish cohort. Children who were never breastfed had a twofold increased risk of type 1 diabetes compared with those who were breastfed (HR 2.29 [95% CI 1.14–4.61] for no breastfeeding vs. any breastfeeding for ≥12 months). Among those who were breastfed, however, the incidence of type 1 diabetes was independent of duration of both full breastfeeding (HR per month 0.99 [95% CI 0.97–1.01]) and any breastfeeding (0.97 [0.92–1.03]).CONCLUSIONS: Suggestive evidence supports the contention that breastfeeding reduces the risk of type 1 diabetes. Among those who were breastfed, however, no evidence indicated that prolonging full or any breastfeeding was associated with a reduced risk of type 1 diabetes.

AB - OBJECTIVE: Our aim was to study the relation between the duration of full and any breastfeeding and risk of type 1 diabetes.RESEARCH DESIGN AND METHODS: We included two population-based cohorts of children followed from birth (1996–2009) to 2014 (Denmark) or 2015 (Norway). We analyzed data from a total of 155,392 children participating in the Norwegian Mother and Child Cohort Study (MoBa) and the Danish National Birth Cohort (DNBC). Parents reported infant dietary practices when their child was 6 and 18 months old. The outcome was clinical type 1 diabetes, ascertained from nationwide childhood diabetes registries. Hazard ratios (HRs) were estimated using Cox regression.RESULTS: Type 1 diabetes was identified in 504 children during follow-up, and the incidence of type 1 diabetes per 100,000 person-years was 30.5 in the Norwegian cohort and 23.5 in the Danish cohort. Children who were never breastfed had a twofold increased risk of type 1 diabetes compared with those who were breastfed (HR 2.29 [95% CI 1.14–4.61] for no breastfeeding vs. any breastfeeding for ≥12 months). Among those who were breastfed, however, the incidence of type 1 diabetes was independent of duration of both full breastfeeding (HR per month 0.99 [95% CI 0.97–1.01]) and any breastfeeding (0.97 [0.92–1.03]).CONCLUSIONS: Suggestive evidence supports the contention that breastfeeding reduces the risk of type 1 diabetes. Among those who were breastfed, however, no evidence indicated that prolonging full or any breastfeeding was associated with a reduced risk of type 1 diabetes.

U2 - 10.2337/dc17-0016

DO - 10.2337/dc17-0016

M3 - Journal article

C2 - 28487451

VL - 40

SP - 920

EP - 927

JO - Diabetes Care

JF - Diabetes Care

SN - 0149-5992

IS - 7

ER -

ID: 188197324