Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal. / Mortensen, Erik L.; Reinisch, June M.; Sanders, Stephanie A.; Rubin, Donald B.

In: Ugeskrift for Laeger, Vol. 158, No. 46, 1996, p. 6589-6594.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mortensen, EL, Reinisch, JM, Sanders, SA & Rubin, DB 1996, 'Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal', Ugeskrift for Laeger, vol. 158, no. 46, pp. 6589-6594.

APA

Mortensen, E. L., Reinisch, J. M., Sanders, S. A., & Rubin, D. B. (1996). Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal. Ugeskrift for Laeger, 158(46), 6589-6594.

Vancouver

Mortensen EL, Reinisch JM, Sanders SA, Rubin DB. Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal. Ugeskrift for Laeger. 1996;158(46):6589-6594.

Author

Mortensen, Erik L. ; Reinisch, June M. ; Sanders, Stephanie A. ; Rubin, Donald B. / Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal. In: Ugeskrift for Laeger. 1996 ; Vol. 158, No. 46. pp. 6589-6594.

Bibtex

@article{8466e19a6bbc466597d61d54a5113b99,
title = "Intelligensdefekter som senf{\o}lge af pr{\ae}natal eksposition for phenobarbital - Fenemal",
abstract = "Two double-blind studies were conducted on two independent samples of adult men prenatally exposed to phenobarbital and matched control samples using two different measures of general intelligence (WAIS and a draft board test (BPP)). The two studies included 33 and 81 exposed adult men respectively, and the two control groups included 52 and 101 unexposed men matched on a wide spectrum of maternal variables recorded pre- and perinatally. Based on data from control subjects, regression models were built relating intelligence scores to relevant preexposure matching variables. Models generated predicted scores for each exposed subject. Men exposed prenatally to phenobarbital had significantly lower verbal intelligence scores than predicted. Lower socioeconomic status and being the offspring of an unwanted pregnancy increased the magnitude of the negative effects. Exposure which includes the last trimester was the most detrimental. Physicians are urged to use increased caution in prescribing such medications during pregnancy or to premature neonates.",
author = "Mortensen, {Erik L.} and Reinisch, {June M.} and Sanders, {Stephanie A.} and Rubin, {Donald B.}",
year = "1996",
language = "Tysk",
volume = "158",
pages = "6589--6594",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "46",

}

RIS

TY - JOUR

T1 - Intelligensdefekter som senfølge af prænatal eksposition for phenobarbital - Fenemal

AU - Mortensen, Erik L.

AU - Reinisch, June M.

AU - Sanders, Stephanie A.

AU - Rubin, Donald B.

PY - 1996

Y1 - 1996

N2 - Two double-blind studies were conducted on two independent samples of adult men prenatally exposed to phenobarbital and matched control samples using two different measures of general intelligence (WAIS and a draft board test (BPP)). The two studies included 33 and 81 exposed adult men respectively, and the two control groups included 52 and 101 unexposed men matched on a wide spectrum of maternal variables recorded pre- and perinatally. Based on data from control subjects, regression models were built relating intelligence scores to relevant preexposure matching variables. Models generated predicted scores for each exposed subject. Men exposed prenatally to phenobarbital had significantly lower verbal intelligence scores than predicted. Lower socioeconomic status and being the offspring of an unwanted pregnancy increased the magnitude of the negative effects. Exposure which includes the last trimester was the most detrimental. Physicians are urged to use increased caution in prescribing such medications during pregnancy or to premature neonates.

AB - Two double-blind studies were conducted on two independent samples of adult men prenatally exposed to phenobarbital and matched control samples using two different measures of general intelligence (WAIS and a draft board test (BPP)). The two studies included 33 and 81 exposed adult men respectively, and the two control groups included 52 and 101 unexposed men matched on a wide spectrum of maternal variables recorded pre- and perinatally. Based on data from control subjects, regression models were built relating intelligence scores to relevant preexposure matching variables. Models generated predicted scores for each exposed subject. Men exposed prenatally to phenobarbital had significantly lower verbal intelligence scores than predicted. Lower socioeconomic status and being the offspring of an unwanted pregnancy increased the magnitude of the negative effects. Exposure which includes the last trimester was the most detrimental. Physicians are urged to use increased caution in prescribing such medications during pregnancy or to premature neonates.

UR - http://www.scopus.com/inward/record.url?scp=0030580213&partnerID=8YFLogxK

M3 - Tidsskriftartikel

C2 - 8966823

AN - SCOPUS:0030580213

VL - 158

SP - 6589

EP - 6594

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 46

ER -

ID: 275900733