Research areas

  1. Published

    Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

    Conti, P., De Amici, M., Roda, G., Pinto, A., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte, Bräuner, Hans & De Micheli, C., 2007, In: Tetrahedron. 63, 10, p. 2249-2256

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

    Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, Birgitte, Madsen, Ulf, Frydenvang, Karla Andrea, Colombo, A. & De Micheli, C., 2007, In: European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid

    Jørgensen, Charlotte Grube, Clausen, Rasmus Prætorius, Hansen, K. B., Bräuner, Hans, Nielsen, Birgitte, Metzler, B., Kehler, J., Krogsgaard-Larsen, Povl & Madsen, Ulf, 2007, In: Organic & Biomolecular Chemistry. 5, 3, p. 463-471

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In: Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In: Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Synthesis of bicyclic acidic amino acids conformationally restricted mimetics of Glu or Asp & work towards the enantioselective total synthesis of cardinalin 3

    Sejberg, J. J. P., 2009, København: Det Farmaceutiske Fakultet. 169 p.

    Research output: Book/ReportPh.D. thesisResearch

  7. Published

    Synthesis of conformationally constrained glutamic acid homologues and investigation of their pharmacological profiles

    Conti, P., Pinto, A., Tamborini, L., Grazioso, G., De Sarro, G., Bräuner, Hans, Szabo, G., Hársing, L. G. & De Micheli, C., 2007, In: ChemMedChem. 2, 11, p. 1639-1647 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Synthesis of enantiopure 3-substituted morpholines

    Bornholdt, J., Felding, J. & Kristensen, Jesper Langgaard, 2010, In: Journal of Organic Chemistry. 75, 21, p. 7454-7457

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Synthesis of imidazole-4(5)-acetic acid analogues: for characterizing the ionotropic GABA receptors

    Madsen, C., 2010, København: Det Farmaceutiske Fakultet. 186 p.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Synthesis of new GABA uptake inhibitors

    Jørgensen, L., 2011, København: Det Farmaceutiske Fakultet. 157 p.

    Research output: Book/ReportPh.D. thesisResearch

  12. Published

    Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

    Pinto, A., Conti, P., Grazioso, G., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte & De Micheli, C., 1 Feb 2011, In: European Journal of Medicinal Chemistry. 46, 2, p. 787-793

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Synthesis of the thiazole-thiazoline fragment of largazole analogues

    Diness, Frederik, Nielsen, D. S. & Fairlie, D. P., 2 Dec 2011, In: Journal of Organic Chemistry. 76, 23, p. 9845-9851

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care

    Thomsen, L. A., Winterstein, A. G., Søndergaard, B., Nørgaard, Lotte Stig & Melander, A., 2007, In: Annals of Pharmacotherapy. 41, 9, p. 1411-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Tabletter med løse ender

    Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6

    Research output: Contribution to journalJournal articleResearch

  16. Published

    Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species

    Sprogøe, K., Stærk, Dan, Jäger, A. K., Adsersen, A., Hansen, S. H., Witt, M., Landbo, A. R., Meyer, A. S. & Jaroszewski, J. W., 2007, In: Journal of Natural Products. 70, 9, p. 1472-1477

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In: Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

    Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Targeting protein-protein interactions: inhibitors of c-Myc/Max and PDZ domain proteins

    Bach, Anders, 2009, København: Det Farmaceutiske Fakultet. 196 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published
  21. Published

    Teaching social sciences to undergraduate pharmacy students: An international survey

    Ryan, K., Bissell, P., Anderson, C., Traulsen, Janine Marie & Sleath, B., 2007, In: Pharmacy Education. 1, p. 1-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Temocene: the porphycene analogue of temoporfin (Foscan®)

    Garcia-Diaz, M., Sanchez-Garcia, D., Nonell, S., Soriano, J., Villanueva, A., Stockert, J. C., Canete, M., Sagrista, M. L. & Mora, M., 1 Jul 2011, In: MedChemComm. 2, 7, p. 616-619 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Textbook of drug design and discovery

    Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.

    Research output: Book/ReportBookEducation

  24. Published

    Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases

    Vandecaetsbeek, I., Christensen, Søren Brøgger, Liu, Huizhen, van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P., 1 May 2011, In: BBA General Subjects. 1813, 5, p. 1118-1127

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development.

    Doan, T. Q. N. & Christensen, Søren Brøgger, Oct 2015, In: Current Pharmaceutical Design. 21, 38, p. 5505-5517 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    The Danish version of the Medication Adherence Report Scale: preliminary validation in cancer pain patients: preliminary validation in cancer pain patients

    Jacobsen, Ramune, Møldrup, C., Christrup, Lona Louring, Sjøgren, P. & Hansen, O. B., 2009, In: Pain Practice. 9, 1, p. 1-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The Danish version of the questionnaire on pain communication: preliminary validation in cancer patients: preliminary validation in cancer patients

    Jacobsen, Ramune, Møldrup, C., Christrup, Lona Louring, Sjøgren, P. & Hansen, O. B., 2009, In: Acta Anaesthesiologica Scandinavica. 53, 6, p. 807-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The EUFEPS workshop on institutional peer review "The ultimate tool to advance the pharmaceutical sciences?" A continuing story: A continuing story

    Crommelin, D. J. A. & Bjerrum, Ole Jannik, 2008, In: European Journal of Pharmaceutical Sciences. 35, 4, p. 361-364

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses

    Guetg, N., Seddik, R., Vigot, R., Turecek, R., Gassmann, M., Vogt, K. E., Bräuner, Hans, Shigemoto, R., Kretz, O., Frotscher, M., Kulik, Á. & Bettler, B., 2009, In: Journal of Neuroscience. 29, 5, p. 1414-1423

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The GTP-cyclohydrolase deficient mouse shows reduced acute pain perception

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie & Møller, L. B., 2010.

    Research output: Contribution to conferencePosterCommunication

  31. Published

    The N-vinyl group as a protection group of the preparation of 3(5)-substituted pyrazoles via bromine-lithium exchange

    Iddon, B., Tønder, J. E., Hosseini, M. & Begtrup, M. E., 2007, In: Tetrahedron. 63, 1, p. 56-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice

    Diep, T. A., Golbas, G. & Hansen, Harald S., 28 Jun 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  33. Published

    The SMARTCyp cytochrome P450 metabolism prediction server

    Rydberg, P., Gloriam, David E. & Olsen, L., 1 Dec 2010, In: Bioinformatics. 26, 23, p. 2988-2989

    Research output: Contribution to journalLetterResearchpeer-review

  34. Published

    The accuracy of geometries for iron porphyrin complexes from density functional theory

    Rydberg, P. Å. A. & Olsen, L., 2009, In: Journal of Physical Chemistry A. 113, 43, p. 11949-11953

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The antagonistic effect of antipsychotic drugs on a HEK293 cell line stably expressing human alpha(1A1)-adrenoceptors

    Nourian, Z., Mulvany, M. J., Nielsen, K. B., Pickering, Darryl S & Kristensen, T., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 32-40

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

    Champion, E., Remaud-Simeon, M., Skov, L. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 12, p. 1309-1314

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The calcium-sensing receptor and calcimimetics in blood pressure modulation

    Smajilovic, S., Yano, S., Jabbari, R. & Tfelt-Hansen, J., Oct 2011, In: British Journal of Pharmacology. 164, 3, p. 884-893

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers

    Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The cost of health related quality of life in urology

    Holm-Larsen, T., 2008, Det Farmaceutiske Fakultet. 90 p.

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    The cysteine protease RgpB as a biomarker for the periodonto-pathogen Porphyromonas gingivalis: Nanobody selection and assay development

    Skottrup, P. D., Leonard, P., Kaczmarek, J., Veillard, F., Johannes Enghild, J., O'Kennedy, R., Sroka, A., Clausen, Rasmus Prætorius, Potempa, J. & Riise, E. S., 2011.

    Research output: Contribution to conferencePosterResearch

  41. Published

    The diffusion of innovation: factors influencing the uptake of pharmacogenetics

    Nielsen, L. F. & Møldrup, C., 2007, In: Community Genetics. 10, 4, p. 231-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The effect of extracts of Searsia species on epileptiform activity in slices of the mouse cerebral cortex

    Pedersen, M. E., Vestergaard, H. T., Stafford, G. I., van Staden, J. & Jäger, A. K., 2008, In: Journal of Ethnopharmacology. 119, 3, p. 538-541

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The effect of fish oil-supplementation on oxidative burst in healthy young men, measured by whole blood chemiluminescence

    Bartelt, S., Damsgaard, C. T., Timm, M., Hansen, E. W., Hansen, Harald S. & Lauritzen, L., 2007.

    Research output: Contribution to conferencePosterResearch

  44. Published

    The effect of health, socio-economic position, and mode of data collection on non-response in health interview surveys

    Ekholm, O., Gundgaard, J., Rasmussen, N. K. R. & Hansen, E. H., 2010, In: Scandinavian Journal of Public Health. 38, 7, p. 699-706 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The effect of non-response on estimates of health care utilisation: linking health surveys and registers

    Gundgaard, J., Ekholm, O., Hansen, E. H. & Rasmussen, N. K., 2008, In: European Journal of Public Health. 18, 2, p. 189-194

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The effect of structural characteristics of Lycopodane-type alkaloids on their acetylcholinesterase inhibitory activity in silico

    Halldorsdottir, E., Jaroszewski, J. W. & Olafsdottir, E., Aug 2010, In: Planta Medica. 76, 12, p. 1212

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    The emerging role of promiscuous 7TM receptors as chemosensors for food intake

    Wellendorph, Petrine, Johansen, L. D. & Bräuner, Hans, 1 Jan 2010, Incretins and insulin secretion. Litwack, G. (ed.). Amsterdam: Elsevier Editora, Vol. 84. p. 151-184 (Vitamins & hormones, Vol. 84).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  48. Published

    The existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogue

    Bondensgaard, K., Breinholt, J., Madsen, D., Omkvist, D. H., Kang, L., Worsaae, A., Becker, P., Bruun Schiødt, C. & Hjorth, S. A., 2007, In: Journal of Biological Chemistry. 282, 32, p. 23326-23336

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The four human ¿-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay

    Kvist, T., Christiansen, B., Jensen, Anders A. & Bräuner, Hans, 2009, In: Combinatorial Chemistry & High Throughput Screening. 12, 3, p. 241-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

    Clausen, Rasmus Prætorius, Naur, P., Kristensen, Anders Skov, Greenwood, J. R., Strange, M., Bräuner, Hans, Jensen, Anders A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, Birgitte, Pickering, Darryl S, Brehm, L., Gajhede, Michael, Krogsgaard-Larsen, Povl & Kastrup, Jette Sandholm Jensen, 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4911-4922

    Research output: Contribution to journalJournal articleResearchpeer-review