Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial

Research output: Contribution to journalJournal articleResearchpeer-review

  • J Donald Easton
  • Renato D Lopes
  • M Cecilia Bahit
  • Daniel M Wojdyla
  • Christopher B Granger
  • Lars Wallentin
  • Marco Alings
  • Shinya Goto
  • Basil S Lewis
  • Mårten Rosenqvist
  • Michael Hanna
  • Puneet Mohan
  • John H Alexander
  • Hans-Christoph Diener
  • ARISTOTLE Committees and Investigators
  • Torp-Pedersen, Christian Tobias
In the ARISTOTLE trial, the rate of stroke or systemic embolism was reduced by apixaban compared with warfarin in patients with atrial fibrillation (AF). Patients with AF and previous stroke or transient ischaemic attack (TIA) have a high risk of stroke. We therefore aimed to assess the efficacy and safety of apixaban compared with warfarin in prespecified subgroups of patients with and without previous stroke or TIA.
Original languageEnglish
JournalThe Lancet Neurology
Volume11
Issue number6
Pages (from-to)503-11
Number of pages9
ISSN1474-4422
DOIs
Publication statusPublished - Jun 2012

ID: 48592372