Jørgen Hilden
Associate professor emeritus, Associate Professor emeritus
- 2021
- Published
A screening method to spot biomarkers that may warn of serious events in a chronic disease - illustrated by cardiological CLARICOR trial data
Winkel, P., Hilden, Jørgen, Jakobsen, J. C., Lindschou, J., Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J., Bjerre, M. & Gluud, C., 2021, In: Clinical Chemistry and Laboratory Medicine. 59, 11, p. 1852-1860 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trajectories in severe persistent pain after groin hernia repair: A retrospective analysis
Jensen, E. K., Bäckryd, E., Hilden, Jørgen & Werner, M. U., 2021, In: Scandinavian Journal of Pain. 21, 1, p. 70-80 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease
Schroder, J., Jakobsen, J. C., Winkel, P., Hilden, Jørgen, Jensen, G. B., Sajadieh, Ahmad, Larsson, A., Ärnlöv, J., Harutyunyan, M., Johansen, Julia Sidenius, Kjøller, E., Gluud, C. & Kastrup, J., 2020, In: Journal of the American Heart Association. 9, 5, e01463.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic value of 12 novel cardiological biomarkers in stable coronary artery disease: A 10-year follow-up of the placebo group of the Copenhagen CLARICOR trial
Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Iversen, Kasper, Bjerre, M., Larsson, A., Ärnlöv, J. & Gluud, C., 2020, In: BMJ Open. 10, 8, 7 p., e033720.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum osteoprotegerin as a long-term predictor for patients with stable coronary artery disease and its association with diabetes and statin treatment: A CLARICOR trial 10-year follow-up substudy
Bjerre, M., Hilden, Jørgen, Winkel, P., Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J., Jakobsen, J. C. & Gluud, C., 2020, In: Atherosclerosis. 301, p. 8-14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Circulating endostatin as a risk factor for cardiovascular events in patients with stable coronary heart disease: A CLARICOR trial sub-study
Ruge, T., Carlsson, A. C., Kjøller, E., Hilden, Jørgen, Kolmos, H. J., Sajadieh, Ahmad, Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Arnlov, J., 2019, In: Atherosclerosis. 284, p. 202-208 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Power estimations for non-primary outcomes in randomised clinical trials
Jakobsen, J. C., Ovesen, C., Winkel, P., Hilden, Jørgen, Gluud, C. & Wetterslev, J., 2019, In: BMJ Open. 9, 6, 3 p., e027092.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy
Carlsson, A. C., Ruge, T., Kjøller, E., Hilden, Jørgen, Kolmos, H. J., Sajadieh, Ahmad, Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Ärnlöv, J., 1 May 2018, In: Journal of the American Heart Association. 7, 9, 11 p., e008299.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cathepsin B and S as markers for cardiovascular risk and all-cause mortality in patients with stable coronary heart disease during 10 years: a CLARICOR trial sub-study
Wuopio, J., Hilden, Jørgen, Bring, C., Kastrup, J., Sajadieh, Ahmad, Jensen, G. B., Kjøller, E., Kolmos, H. J., Larsson, A., Jakobsen, J. C., Winkel, P., Gluud, C., Carlsson, A. C. & Ärnlöv, J., 2018, In: Atherosclerosis. 278, p. 97-102 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimum clinically important differences in chronic pain vary considerable by baseline pain and methodological factors: systematic review of empirical studies
Olsen, Mette Frahm, Bjerre, E., Hansen, M. D., Tendal, B., Hilden, Jørgen & Hróbjartsson, A., 2018, In: Journal of Clinical Epidemiology. 101, p. 87-106.e2 22 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course
Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Jensen, G., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Arnlov, J. & Gluud, C., 2018, In: Open Heart. 5, 2, 10 p., e000808.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Pain relief that matters to patients: systematic review of empirical studies assessing the minimum clinically important difference in acute pain
Olsen, Mette Frahm, Bjerre, E., Hansen, M. D., Hilden, Jørgen, Landler, N. E., Tendal, B. & Hróbjartsson, A., 2017, In: B M C Medicine. 15, 18 p., 35.Research output: Contribution to journal › Review › Research › peer-review
- Published
Predictors for major cardiovascular outcomes in stable ischaemic heart disease (PREMAC): statistical analysis plan for data originating from the CLARICOR (clarithromycin for patients with stable coronary heart disease) trial
Winkel, P., Jakobsen, J. C., Hilden, Jørgen, Lange, Theis, Jensen, G. B., Kjøller, E., Sajadieh, Ahmad, Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J. & Gluud, C., 2017, In: Diagnostic and Prognostic Research. 1, 8 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?
Pepe, M. S., Janes, H., Li, C. I., Bossuyt, P. M., Feng, Z. & Hilden, Jørgen, May 2016, In: Clinical Chemistry. 62, 5, p. 737-742 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The matching quality of experimental and control interventions in blinded pharmacological randomised clinical trials: a methodological systematic review
Bello, S., Wei, M., Hilden, Jørgen & Hróbjartsson, A., 13 Feb 2016, In: BMC Medical Research Methodology. 16, p. 1-12 12 p., 18.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
The Net Reclassification Index (NRI): A Misleading Measure of Prediction Improvement Even with Independent Test Data Sets
Pepe, M. S., Fan, J., Feng, Z., Gerds, Thomas Alexander & Hilden, Jørgen, Oct 2015, In: Statistics in BioSciences. 7, 2, p. 282-295 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clarithromycin for stable coronary heart disease increases all-cause and cardiovascular mortality and cerebrovascular morbidity over 10years in the CLARICOR randomised, blinded clinical trial
Winkel, P., Hilden, Jørgen, Hansen, J. F., Kastrup, J., Kolmos, H. J., Kjøller, E., Boje Jensen, G., Skoog, M., Lindschou, J., Gluud, C. & CLARICOR Trial Group, C. T. G., Mar 2015, In: International Journal of Cardiology. 182, p. 459-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: The CLARICOR trial
Bjerre, M., Hilden, Jørgen, Kastrup, J., Skoog, M., Hansen, J. F., Kolmos, H. J., Jensen, G. B., Kjøller, E., Winkel, P., Flyvbjerg, A., Gluud, C. & CLARICOR Trial Group, C. T. G., Nov 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 8, p. 657-664 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A note on the evaluation of novel biomarkers: do not rely on integrated discrimination improvement and net reclassification index
Hilden, Jørgen & Gerds, Thomas Alexander, 30 Aug 2014, In: Statistics in Medicine. 33, 19, p. 3405-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calibration of models is not sufficient to justify NRI
Gerds, Thomas Alexander & Hilden, Jørgen, 30 Aug 2014, In: Statistics in Medicine. 33, 19, p. 3419-20 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Agreement between public register and adjudication committee outcome in a cardiovascular randomized clinical trial
Kjøller, E., Hilden, Jørgen, Winkel, P., Galatius, S., Frandsen, N. J., Jensen, G. B., Fischer Hansen, J., Kastrup, J., Jespersen, C. M., Hildebrandt, P., Kolmos, H. J., Gluud, C. & CLARICOR Trial Group, C. T. G., Aug 2014, In: American Heart Journal. 168, 2, p. 197–204.e4 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bias due to lack of patient blinding in clinical trials: A systematic review of trials randomizing patients to blind and nonblind sub-studies
Hróbjartsson, A., Emanuelsson, F., Skou Thomsen, A. S., Hilden, Jørgen & Brorson, Stig, Aug 2014, In: International Journal of Epidemiology. 43, 4, p. 1272-1283 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Observer bias in randomized clinical trials with time-to-event outcomes: systematic review of trials with both blinded and non-blinded outcome assessors
Hróbjartsson, A., Thomsen, A. S. S., Emanuelsson, F., Tendal, B., Rasmussen, J. V., Hilden, Jørgen, Boutron, I., Ravaud, P. & Brorson, Stig, Jun 2014, In: International Journal of Epidemiology. 43, 3, p. 937-948 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On NRI, IDI, and "good-looking" statistics with nothing underneath
Hilden, Jørgen, Mar 2014, In: Epidemiology (Cambridge, Mass.). 25, 2, p. 265-7 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Risk stratification in stable coronary artery disease is possible at cardiac troponin levels below conventional detection and is improved by use of N-terminal pro-B-type natriuretic peptide
Lyngbæk, S., Winkel, P., Gøtze, J. P., Kastrup, J., Gluud, C., Kolmos, H. J., Kjøller, E., Jensen, G. B., Hansen, J. F., Hildebrandt, P., Hilden, Jørgen & CLARICOR Trial Group, C. T. G., 2014, In: European Journal of Preventive Cardiology. 21, 10, p. 1275-1284 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Serum YKL-40 predicts long-term mortality in patients with stable coronary disease: a prognostic study within the CLARICOR trial
Harutyunyan, M., Goetze, Jens P. , Winkel, P., Johansen, Julia Sidenius, Hansen, J. F., Jensen, G. B., Hilden, Jørgen, Kjøller, E., Kolmos, H. J., Gluud, C. & Kastrup, J., Jul 2013, In: Immunobiology. 218, 7, p. 945-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Observer bias in randomized clinical trials with measurement scale outcomes: a systematic review of trials with both blinded and nonblinded assessors
Hróbjartsson, A., Thomsen, A. S. S., Emanuelsson, F., Tendal, B., Hilden, Jørgen, Boutron, I., Ravaud, P. & Brorson, Stig, 5 Mar 2013, In: C M A J. 185, 4, p. E201-11Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors
Hróbjartsson, A., Thomsen, A. S. S., Emanuelsson, F., Tendal, B., Hilden, Jørgen, Boutron, I., Ravaud, P. & Brorson, Stig, 27 Feb 2012, In: B M J (Online). 344, p. e1119Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Observer bias in randomised clinical trials with binary outcomes: systematic review of trials with both blinded and non-blinded outcome assessors
Hróbjartsson, A., Thomsen, A. S. S., Emanuelsson, F., Tendal, B., Hilden, Jørgen, Boutron, I., Ravaud, P. & Brorson, S., 27 Feb 2012, In: B M J (Clinical Research Edition). 344, 1 p., e1119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Good interobserver agreement was attainable on outcome adjudication in patients with stable coronary heart disease
Kjoller, E., Hilden, Jørgen, Winkel, P., Frandsen, N. J., Galatius, S., Jensen, G., Kastrup, J., Hansen, J. F., Kolmos, H. J. J., Jespersen, C. M., Hildebrandt, P., Gluud, C. N. & CLARICOR Trial Group, C. T. G., 2012, In: Journal of Clinical Epidemiology. 65, 4, p. 444-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
High-sensitivity C-reactive protein and N-terminal pro-B-type natriuretic peptide in patients with stable coronary artery disease: a prognostic study within the CLARICOR Trial
Harutyunyan, M. J., Mathiasen, A. B., Winkel, P., Goetze, Jens P. , Hansen, J. F., Hildebrandt, P., Jensen, G. B., Hilden, Jørgen, Jespersen, C. M., Kjøller, E., Kolmos, H. J., Gluud, C., Kastrup, J. & CLARICOR Trial Group, C. T. G., 1 Feb 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 1, p. 52-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy associated plasma protein-A as a marker for myocardial infarction and death in patients with stable coronary artery disease: A prognostic study within the CLARICOR Trial
Iversen, Kasper, Teisner, B., Winkel, P., Gluud, C., Kjøller, E., Kolmos, H. J., Hildebrandt, P. R., Hilden, Jørgen, Kastrup, J. & The CLARICOR Trial Group, T. C. T. G., 1 Jan 2011, In: Atherosclerosis. 214, 1, p. 203-208 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of the diagnostic accuracy of laboratory tests using receiver operating characteristic curves; approved guideline - second edition
Kroll, M., Biswas, B., Budd, J., Durham, P., Gorman, R., Gwise, T., Halim, A., Hatjimihail, A., Hilden, Jørgen & Kyunghee, S., 2011, In: Clinical and Laboratory Standards Institute Document. 31, 23, p. 1-45 45 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excess sudden cardiac deaths after short-term clarithromycin administration in the CLARICOR trial: why is this so, and why are statins protective?
Winkel, P., Hilden, Jørgen, Hansen, J. F., Hildebrandt, P., Kastrup, J., Kolmos, H. J., Kjøller, E., Jespersen, C. M., Gluud, C., Jensen, G. & CLARICOR Trial, G., 2011, In: Cardiology. 118, 1, p. 63-67Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Statin treatment prevents increased cardiovascular and all-cause mortality associated with clarithromycin in patients with stable coronary heart disease
Jensen, G. B., Hilden, J., Als-Nielsen, B., Damgaard, M., Hansen, J. F., Hansen, S., Helø, O. H., Hildebrandt, P., Kastrup, J., Kolmos, H. J., Kjøller, E., Lind, I., Nielsen, H., Petersen, L., Jespersen, C. M., Gluud, C., CLARICOR Trial Group, Jensen, G. B., Hilden, J., Als-Nielsen, B. & 14 others, , 1 Feb 2010, In: Journal of Cardiovascular Pharmacology. 55, 2, p. 123-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous use of serum IgG and IgM for risk scoring of suspected early Lyme borreliosis: graphical and bivariate analyses
Dessau, R. B., Ejlertsen, T. & Hilden, Jørgen, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 4, p. 313-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Betydning af opholdstid og antal flytninger på asylbørns psykiske helbred - sekundærpublikation
Jervelund, Signe Smith, Nørredam, Marie Louise, Christiansen, K. L., Obel, C., Hilden, Jørgen & Krasnik, Allan, 2009, In: Ugeskrift for læger. 171, 12, p. 981-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bias in Scientific Studies
Hilden, Jørgen, 2009, Encyclopedia Of Medical Decision Making. Kattan, M. (ed.). USA: SAGE Publications, p. 80-85 6 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Boolean Algebra and Nodes
Hilden, Jørgen, 2009, Encyclopedia Of Medical Decision Making. Kattan, M. W. (ed.). USA: SAGE Publications, p. 94-98 5 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Compliance with and short-term adverse events from clarithromycin versus placebo in patients with stable coronary heart disease: the CLARICOR trial
Jespersen, C. M., Kolmos, H. J., Frydendall, N., Hilden, Jørgen, Gluud, C., Hansen, J. F. & CLARICOR Trial Group, C. T. G., 2009, In: Journal of Antimicrobial Chemotherapy. 64, 2, p. 411-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expected Value of Sample Information
Hilden, Jørgen, 2009, Expected Value of Sample Information: Net Benefit of Sampling. USA: SAGE Publications, p. 481-86 6 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Povl Heiberg's 1897 methodological study on the statistical method as an aid in therapeutic trials
Gluud, C. & Hilden, Jørgen, 2009, In: Preventive Medicine. 48, 6, p. 600-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Budget impact analysis and its rational basis
Hilden, Jørgen, 2008, In: Medical Decision Making. 28, 4, p. 460-1 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clarithromycin for 2 Weeks for Stable Coronary Heart Disease: 6-Year Follow-Up of the CLARICOR Randomized Trial and Updated Meta-Analysis of Antibiotics for Coronary Heart Disease.
Gluud, C., Als-Nielsen, B., Damgaard, M., Fischer Hansen, J., Hansen, S., Helø, O. H., Hildebrandt, P., Hilden, J., Jensen, G. B., Kastrup, J., Kolmos, H. J., Kjøller, E., Lind, I., Nielsen, H., Petersen, L., Jespersen, C. M., CLARICOR Trial Group, Gluud, C., Als-Nielsen, B., Damgaard, M. & 13 others, , 2008, In: Cardiology. 111, 4, p. 280-287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials (vol 36, pg 847, 2007)
Pildal, J., Hrobjartsson, A., Jorgensen, K. J., Hilden, Jørgen, Altman, D. G. & Gotzsche, P. C., 2008, In: International Journal of Epidemiology. 37, 2, p. 422-422 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mental health among children seeking asylum in Denmark--the effect of length of stay and number of relocations: a cross-sectional study
Nørredam, Marie Louise, Nielsen, S., Christiansen, K., Obel, C., Hilden, Jørgen & Krasnik, Allan, 2008, In: BMC Public Health. 8, 293Research output: Contribution to journal › Journal article › Research › peer-review
- Published
More studies on outcomes using biochemical diagnostic tests are needed: findings from the Danish Society of Clinical Biochemistry
Madsen, J. S., Nybo, M., Magid, E., Hilden, Jørgen, Hornung, N., Larsen, T. B., Jørgensen, L. & Jørgensen, P. E., 2008, In: Clinical Chemistry. 54, 7, p. 1254-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organisational factors influencing asylum-seeking children's mental health
Jervelund, Signe Smith, Nørredam, Marie Louise, Christiansen, K. L., Obel, C., Hilden, Jørgen & Krasnik, Allan, 2008. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Systematic reviews of diagnostic test accuracy
Leeflang, M. M. G., Deeks, J. J., Gatsonis, C., Bossuyt, P. M. M. & Hilden, Jørgen, 2008, In: Annals of Internal Medicine. 149, 12, p. 889-97 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Osteoporosis Self-Assessment Tool versus alternative tests for selecting postmenopausal women for bone mineral density assessment: a comparative systematic review of accuracy
Rud, B., Hilden, Jørgen, Hyldstrup, L. & Hróbjartsson, A., 2008, In: Osteoporosis International.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 314941
Most downloads
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172
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Pain relief that matters to patients: systematic review of empirical studies assessing the minimum clinically important difference in acute pain
Research output: Contribution to journal › Review › Research › peer-review
Published -
160
downloads
10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
151
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Predictors for major cardiovascular outcomes in stable ischaemic heart disease (PREMAC): statistical analysis plan for data originating from the CLARICOR (clarithromycin for patients with stable coronary heart disease) trial
Research output: Contribution to journal › Journal article › Research › peer-review
Published