Research areas

  1. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters

    Andersen, J., Kristensen, Anders Skov, Bang-Andersen, B. & Strømgaard, Kristian, 2009, In: Chemical Communications. 25, p. 3677-3692

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients

    Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230

    Research output: Contribution to journalReviewResearch

  3. Published

    Receptorer i historisk og nutidig belysning

    Bräuner, Hans, 2009, In: Carlsbergfondet. Aarsskrift. p. 30-35

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy

    Keiding, S., Iversen, P., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Gjedde, A., Schousboe, Arne & Vilstrup, H., 2009, In: Journal of Neurochemistry. s1, p. 269-270

    Research output: Contribution to journalConference abstract in journalResearch

  5. Published

    Rheological behaviour of poly(N-isopropyl acrylamide) in water-acetone mixtures

    Munk, T. P., Hietala, S., Kalliomäki, K., Nuopponen, M., Tenhu, H., Tian, F., Rantanen, Jukka & Baldursdóttir, S. G., 2009, In: Nordic Rheology Society Annual Transactions. 17, p. 113-118 6 p.

    Research output: Contribution to journalConference articleResearch

  6. Published

    Risk assessment of contaminants in sewage sludge applied on Norwegian soils: opinion of the panel on contaminants in the Norwegian Scientific Committee for Food Safety

    Sundstøl Eriksen, G., Amundsen, C. E., Bernhoft, A., Eggen, T., Grave, K., Halling-Sørensen, B., Källqvist, T., Sogn, T. & Sverdrup, L., 2009, Oslo: Norwegian Scientific Committee for Food Safety. 208 p.

    Research output: Book/ReportReportCommunication

  7. Published

    Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents

    Walls, Anne Byriel, Heimbürger, C., Bouman, S., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Neuroscience. 158, 1, p. 284-292

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Role of active metabolites in the use of opioids

    Coller, J. K., Christrup, Lona Louring & Somogyi, A. A., 2009, In: European Journal of Clinical Pharmacology. 65, 2, p. 121-139

    Research output: Contribution to journalReviewResearch

  9. Published

    Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy

    Grohganz, Holger, Fonteyne, M., Skibsted, E., Falck, T., Palmqvist, B. & Rantanen, Jukka, 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, p. 901-907

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C. S., Larsen, Susan Weng, Jensen, H., Yaghmur, Anan & Østergaard, Jesper, 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journalReviewResearch

  11. Published

    SHOP: receptor-based scaffold hopping by GRID-based similarity searches

    Bergmann, R., Liljefors, T., Sørensen, M. D. & Zamora, I., 2009, In: Journal of Chemical Information and Modeling. 49, 3, p. 658-669

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

    Maher, S., Leonard, T. W., Jacobsen, Jette & Brayden, D. J., 2009, In: Advanced Drug Delivery Reviews. p. 1427-1449

    Research output: Contribution to journalReviewResearch

  13. Published

    Sample preparation and separation techniques for bioanalysis of morphine and related substances

    Hansen, S. H., 2009, In: Journal of Separation Science. 32, p. 825-834

    Research output: Contribution to journalReviewResearch

  14. Published

    Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

    Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Simulating permeability and drug absorption

    Steffansen, B. & Rapin, N. P. J., 2009.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Simultaneous evaluation of ligand binding properies and protein size by electrophoresis and taylor dispersion in capillaries

    Østergaard, Jesper & Jensen, H., 2009, In: Analytical Chemistry. 81, 20, p. 8644-8648

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Site-site interactions enhances intramolecular electron transfer in streptomyces coelicolor laccase

    Farver, O., Tepper, A. W. J. W., Wherland, S., Canters, G. W. & Pecht, I., 2009, In: Journal of the American Chemical Society. 131, p. 18226-18227

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Skræddersyede proteiner: uden naturens begrænsninger

    Strømgaard, Kristian, Jensen, M. S. & Kristensen, Anders Skov, 2009, In: Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  19. Published

    Solid form screening: A review

    Aaltonen, J., Allesø, M., Mirza, S., Koradia, V. S., Gordon, K. C. & Rantanen, Jukka, 2009, In: European Journal of Pharmaceutics and Biopharmaceutics. 71, 1, p. 23-37

    Research output: Contribution to journalReviewResearch

  20. Published

    Solvent-mediated solid phase transformations of carbamazepine: effects of simulated intestinal fluid and fasted state simulated intestinal fluid

    Lehto, P., Aaltonen, J., Tenho, M., Rantanen, Jukka, Hirvonen, J., Tanninen, V. P. & Peltonen, L., 2009, In: Journal of Pharmaceutical Sciences. 98, 3, p. 985-996

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Sparing the ortho-position in nucleophilic aromatic substitution-specific displacement of the 4-SePh group in 2,4-bis(phenylseleno)nitrobenzene

    Stuhr-Hansen, N., Götze, T. F., Henriksen, L., Sølling, Theis Ivan, Langkilde, Annette Eva & Sørensen, H. O., 2009, In: Heteroatom Chemistry. 20, 2, p. 101-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators

    Nordly, P. J., Madsen, H. B., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Expert Opinion on Drug Delivery. 6, 7, p. 1-16

    Research output: Contribution to journalReviewResearch

  23. Published

    Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors

    Sivaprakasam, M., Hansen, K. B., David, O., Nielsen, Birgitte, Traynelis, S. F., Clausen, Rasmus Prætorius, Couty, F. & Bunch, Lennart, 2009, In: ChemMedChem. 4, 1, p. 110-117

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Structural characterisation and dehydration behaviour of siramesine hydrochloride

    Zimmermann, A., Tian, F., Lopez de Diego, H., Frydenvang, Karla Andrea, Rantanen, Jukka, Elema, M. R. & Hovgaard, L., 2009, In: Journal of Pharmaceutical Sciences. 98, 10, p. 3596-3607

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structure of a fatty acid-binding protein from Bacillus subtilis determined by sulfur-SAD phasing using in-house chromium radiation

    Nan, J., Zhou, Y., Yang, C., Brostromer, E., Kristensen, O. & Su, X., 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 5, p. 440-448

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Structure of the first PDZ domain of human PSD-93

    Fiorentini, M., Nielsen, A. K., Kristensen, O., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2009, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 65, 12, p. 1254-1257

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Subtype selective kainic acid receptor agonists: discovery and approaches to rational design

    Bunch, Lennart & Krogsgaard-Larsen, Povl, 2009, In: Medicinal Research Reviews. 29, 1, p. 3-28

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension

    Christensen, A., Christrup, Lona Louring, Fabricius, P. E., Chrostowska, M., Wronka, M., Narkiewicz, K. & Hansen, E. H., 2009, In: Blood Pressure. 18, 5, p. 280-285

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

    Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 17, p. 3087-3091

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives

    Armishaw, C., Jensen, Anders A., Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, Peptides for youth: The proceedings of the 20th American peptide symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). Springer, Vol. 611. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  31. Published

    Synthesis of bicyclic acidic amino acids conformationally restricted mimetics of Glu or Asp & work towards the enantioselective total synthesis of cardinalin 3

    Sejberg, J. J. P., 2009, København: Det Farmaceutiske Fakultet. 169 p.

    Research output: Book/ReportPh.D. thesisResearch

  32. Published

    Tabletter med løse ender

    Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6

    Research output: Contribution to journalJournal articleResearch

  33. Published

    Targeting protein-protein interactions: inhibitors of c-Myc/Max and PDZ domain proteins

    Bach, Anders, 2009, København: Det Farmaceutiske Fakultet. 196 p.

    Research output: Book/ReportPh.D. thesisResearch

  34. Published
  35. Published

    The Danish version of the Medication Adherence Report Scale: preliminary validation in cancer pain patients: preliminary validation in cancer pain patients

    Jacobsen, Ramune, Møldrup, C., Christrup, Lona Louring, Sjøgren, P. & Hansen, O. B., 2009, In: Pain Practice. 9, 1, p. 1-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The Danish version of the questionnaire on pain communication: preliminary validation in cancer patients: preliminary validation in cancer patients

    Jacobsen, Ramune, Møldrup, C., Christrup, Lona Louring, Sjøgren, P. & Hansen, O. B., 2009, In: Acta Anaesthesiologica Scandinavica. 53, 6, p. 807-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses

    Guetg, N., Seddik, R., Vigot, R., Turecek, R., Gassmann, M., Vogt, K. E., Bräuner, Hans, Shigemoto, R., Kretz, O., Frotscher, M., Kulik, Á. & Bettler, B., 2009, In: Journal of Neuroscience. 29, 5, p. 1414-1423

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The accuracy of geometries for iron porphyrin complexes from density functional theory

    Rydberg, P. Å. A. & Olsen, L., 2009, In: Journal of Physical Chemistry A. 113, 43, p. 11949-11953

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

    Champion, E., Remaud-Simeon, M., Skov, L. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 12, p. 1309-1314

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers

    Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The four human ¿-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay

    Kvist, T., Christiansen, B., Jensen, Anders A. & Bräuner, Hans, 2009, In: Combinatorial Chemistry & High Throughput Screening. 12, 3, p. 241-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

    Clausen, Rasmus Prætorius, Naur, P., Kristensen, Anders Skov, Greenwood, J. R., Strange, M., Bräuner, Hans, Jensen, Anders A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, Birgitte, Pickering, Darryl S, Brehm, L., Gajhede, Michael, Krogsgaard-Larsen, Povl & Kastrup, Jette Sandholm Jensen, 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4911-4922

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The innate immune responses, adjuvants and delivery systems

    Moghimi, S. M., 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 113-124

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  44. Published

    The ionotropic glutamate receptors: structural and functional studies using the methods of protein crystallography and patch clamp electrophysiology

    Hald, H., 2009, København: Det Farmaceutiske Fakultet. 196 p.

    Research output: Book/ReportPh.D. thesisResearch

  45. Published

    The lay public's explicit and implicit definitions of drugs

    Björnsdóttir, I., Almarsdóttir, A. B. & Traulsen, Janine Marie, 2009, In: Research in Social and Administrative Pharmacy. 5, 1, p. 40-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The lithiation and acyl transfer reactions of phosphine oxides, sulfides and boranes in the synthesis of cyclopropanes

    Clarke, C., Fox, D. J., Pedersen, D. S. & Warren, S., 2009, In: Organic & Biomolecular Chemistry. 7, 7, p. 1329-1336

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The risk of exaggerated risk aversion-: a life and death struggle for molecular imaging

    Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G., Nordberg, A. & 1 others, Brooks, D., 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 10, p. 1693-4 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The role of PAT1 (SLC36A1) in oral drug delivery: absorption of gaboxadol in vitro and in vivo

    Broberg, M. L., 2009, København: Det Farmaceutiske Fakultet. 84 p.

    Research output: Book/ReportPh.D. thesisResearch

  49. Published

    The use of biorelevant dissolution media in determining the region of microemulsion: Implications for in vitro lipid formulation assessment

    Ogbonna, A., Ren, S., Olesen, P. & Mullertz, Anette , 2009.

    Research output: Contribution to conferencePosterResearch

  50. Published

    Thermocleavable p-conjugated polymers: Synthesis and photovoltaic applications

    Helgesen, M., 2009, Roskilde: Danmarks Tekniske Universitet, Risø Nationallaboratoriet for Bæredygtig Energi. 156 p.

    Research output: Book/ReportPh.D. thesisResearch