Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia. / ØRding, H.; Hansen, U.; Skovgaard, L. Theil.

In: Acta Anaesthesiologica Scandinavica Supplementum, Vol. 32, No. 2, 02.1988, p. 121-124.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

ØRding, H, Hansen, U & Skovgaard, LT 1988, 'Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia', Acta Anaesthesiologica Scandinavica Supplementum, vol. 32, no. 2, pp. 121-124. https://doi.org/10.1111/j.1399-6576.1988.tb02699.x

APA

ØRding, H., Hansen, U., & Skovgaard, L. T. (1988). Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia. Acta Anaesthesiologica Scandinavica Supplementum, 32(2), 121-124. https://doi.org/10.1111/j.1399-6576.1988.tb02699.x

Vancouver

ØRding H, Hansen U, Skovgaard LT. Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia. Acta Anaesthesiologica Scandinavica Supplementum. 1988 Feb;32(2):121-124. https://doi.org/10.1111/j.1399-6576.1988.tb02699.x

Author

ØRding, H. ; Hansen, U. ; Skovgaard, L. Theil. / Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia. In: Acta Anaesthesiologica Scandinavica Supplementum. 1988 ; Vol. 32, No. 2. pp. 121-124.

Bibtex

@article{e02abdf5f030408da65e6820dc9f88b1,
title = "Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia",
abstract = "Muscle fiber typing and in vitro contracture tests were performed in 59 patients investigated for susceptibility to malignant hyperthermia (MH). Eighteen patients were found to be susceptible to MH. There was no difference in age or fiber type distribution between MH susceptible and non–susceptible patients. No correlation was found between age and fiber type distribution. Separate analyses for each diagnostic group revealed no relationship between age or fiber type distribution and response to halothane or caffeine. When all caffeine results were pooled, however, there was a significant effect of age on the caffeine specific concentration (the concentration eliciting a contracture of 1 g), but not on the caffeine threshold concentration (the minimal concentration eliciting an increase in tension). It is concluded that age and fiber type distribution have no influence on MH diagnosis, if the protocol of the European MH Group for evaluation of susceptibility to MH is followed.",
keywords = "Anesthetic, caffeine, fiber type, halothane, hyperthermia, malignant, muscle, volatile",
author = "H. {\O}Rding and U. Hansen and Skovgaard, {L. Theil}",
year = "1988",
month = feb,
doi = "10.1111/j.1399-6576.1988.tb02699.x",
language = "English",
volume = "32",
pages = "121--124",
journal = "Acta Anaesthesiologica Scandinavica",
issn = "0001-5172",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Age, fiber type composition and in vitro contracture responses in human malignant hyperthermia

AU - ØRding, H.

AU - Hansen, U.

AU - Skovgaard, L. Theil

PY - 1988/2

Y1 - 1988/2

N2 - Muscle fiber typing and in vitro contracture tests were performed in 59 patients investigated for susceptibility to malignant hyperthermia (MH). Eighteen patients were found to be susceptible to MH. There was no difference in age or fiber type distribution between MH susceptible and non–susceptible patients. No correlation was found between age and fiber type distribution. Separate analyses for each diagnostic group revealed no relationship between age or fiber type distribution and response to halothane or caffeine. When all caffeine results were pooled, however, there was a significant effect of age on the caffeine specific concentration (the concentration eliciting a contracture of 1 g), but not on the caffeine threshold concentration (the minimal concentration eliciting an increase in tension). It is concluded that age and fiber type distribution have no influence on MH diagnosis, if the protocol of the European MH Group for evaluation of susceptibility to MH is followed.

AB - Muscle fiber typing and in vitro contracture tests were performed in 59 patients investigated for susceptibility to malignant hyperthermia (MH). Eighteen patients were found to be susceptible to MH. There was no difference in age or fiber type distribution between MH susceptible and non–susceptible patients. No correlation was found between age and fiber type distribution. Separate analyses for each diagnostic group revealed no relationship between age or fiber type distribution and response to halothane or caffeine. When all caffeine results were pooled, however, there was a significant effect of age on the caffeine specific concentration (the concentration eliciting a contracture of 1 g), but not on the caffeine threshold concentration (the minimal concentration eliciting an increase in tension). It is concluded that age and fiber type distribution have no influence on MH diagnosis, if the protocol of the European MH Group for evaluation of susceptibility to MH is followed.

KW - Anesthetic

KW - caffeine

KW - fiber type

KW - halothane

KW - hyperthermia

KW - malignant

KW - muscle

KW - volatile

UR - http://www.scopus.com/inward/record.url?scp=0023939363&partnerID=8YFLogxK

U2 - 10.1111/j.1399-6576.1988.tb02699.x

DO - 10.1111/j.1399-6576.1988.tb02699.x

M3 - Journal article

C2 - 3348072

AN - SCOPUS:0023939363

VL - 32

SP - 121

EP - 124

JO - Acta Anaesthesiologica Scandinavica

JF - Acta Anaesthesiologica Scandinavica

SN - 0001-5172

IS - 2

ER -

ID: 259166247