Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. Tuberculosisusing dried blood spots

Research output: Contribution to journalJournal articleResearchpeer-review

  • Thomas Blauenfeldt
  • Jan Heyckendorf
  • Sidse Graff Jensen
  • Christoph Lange
  • Camilla Drabe
  • Thomas S. Hermansen
  • Lena De Thurah
  • Lillebæk, Troels
  • Jesper Eugen-Olsen
  • Niels Seersholm
  • Søren Hoff
  • Jesper Bonde
  • Morten Ruhwald

Background: Antigen specific release of IP-10 is the most promising alternative marker to IFN-γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is released in high levels enabling novel approaches such as field friendly dried blood spots (DBS) and molecular detection.

Original languageEnglish
Article numbere105628
JournalPLoS ONE
Volume9
Issue number9
ISSN1932-6203
DOIs
Publication statusPublished - 3 Sep 2014
Externally publishedYes

ID: 247163747