Age-distribution, risk factors and mortality in smokers and non-smokers with acute myocardial infarction: a review. TRACE study group. Danish Trandolapril Cardiac Evaluation

Research output: Contribution to journalJournal articleResearchpeer-review

Smoking is a risk factor for acute myocardial infarction; paradoxically, many studies have shown a lower post-infarct mortality among smokers. There are some important differences between smokers and non-smokers, which might explain the observed difference in mortality: smokers have less multivessel disease and atherosclerosis but are more thrombogenic; thrombolytic therapy seems to be more effective among smokers; smoking might result in an increased out-of-hospital mortality rate, by being more arrhythmogenic; and smokers are on average a decade younger than non-smokers at the time of infarction, and have less concomitant disease. Adjusting for these differences in regression analyses shows that smoking is not an independent risk factor for mortality after acute myocardial infarction. The difference in age and risk factors are responsible for the lower mortality among smokers.
Original languageEnglish
JournalJournal of Cardiovascular Risk
Issue number5
Pages (from-to)307-9
Number of pages2
Publication statusPublished - 1999

Bibliographical note

Keywords: Age Distribution; Denmark; Humans; Myocardial Infarction; Risk Factors; Smoking

ID: 17399316