Systolic heart failure: a prothrombotic state

Research output: Contribution to journalJournal articleResearchpeer-review

Systolic heart failure is a common syndrome whose incidence is expected to increase. Several treatment modalities, such as beta-blockers and angiotensin-converting enzyme inhibitors, improve survival. Whether antithrombotic treatment is effective remains to be elucidated, although observations suggest a prothrombotic state in heart failure. This article focuses on this prothrombotic state and discusses the risk of thromboembolic events, pathophysiological mechanisms, and the potential role of anticoagulant treatment.
Original languageEnglish
JournalSeminars in Thrombosis and Hemostasis
Issue number5
Pages (from-to)497-504
Number of pages8
Publication statusPublished - 1 Jul 2009

Bibliographical note

Keywords: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Fibrinolytic Agents; Heart Failure, Systolic; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Pulmonary Embolism; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin-Angiotensin System; Thromboembolism; Warfarin

ID: 20320180