Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood: A cohort study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood : A cohort study. / Blond, Kim; Vistisen, Dorte; Aarestrup, Julie; Bjerregaard, Lise G.; Hudda, Mohammed T.; Tjønneland, Anne; Allin, Kristine H.; Jørgensen, Marit E.; Jensen, Britt W.; Baker, Jennifer L.

In: Diabetes Research and Clinical Practice, Vol. 191, 110055, 2022.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Blond, K, Vistisen, D, Aarestrup, J, Bjerregaard, LG, Hudda, MT, Tjønneland, A, Allin, KH, Jørgensen, ME, Jensen, BW & Baker, JL 2022, 'Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood: A cohort study', Diabetes Research and Clinical Practice, vol. 191, 110055. https://doi.org/10.1016/j.diabres.2022.110055

APA

Blond, K., Vistisen, D., Aarestrup, J., Bjerregaard, L. G., Hudda, M. T., Tjønneland, A., Allin, K. H., Jørgensen, M. E., Jensen, B. W., & Baker, J. L. (2022). Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood: A cohort study. Diabetes Research and Clinical Practice, 191, [110055]. https://doi.org/10.1016/j.diabres.2022.110055

Vancouver

Blond K, Vistisen D, Aarestrup J, Bjerregaard LG, Hudda MT, Tjønneland A et al. Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood: A cohort study. Diabetes Research and Clinical Practice. 2022;191. 110055. https://doi.org/10.1016/j.diabres.2022.110055

Author

Blond, Kim ; Vistisen, Dorte ; Aarestrup, Julie ; Bjerregaard, Lise G. ; Hudda, Mohammed T. ; Tjønneland, Anne ; Allin, Kristine H. ; Jørgensen, Marit E. ; Jensen, Britt W. ; Baker, Jennifer L. / Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood : A cohort study. In: Diabetes Research and Clinical Practice. 2022 ; Vol. 191.

Bibtex

@article{697ac9fc7b564b368cb3a3a7b88eed80,
title = "Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood: A cohort study",
abstract = "Aims: We examined associations between five body mass index (BMI) trajectories from ages 6–15 years and register-based adult-onset type 2 diabetes mellitus (T2D) and coronary heart disease (CHD) with and without adjustment for adult BMI. Methods: Child and adult BMI came from two Danish cohorts and 13,205 and 13,438 individuals were included in T2D and CHD analyses, respectively. Trajectories were estimated by latent class modelling. Incidence rate ratios (IRRs) were estimated with Poisson regression. Results: In models without adult BMI, compared to the lowest trajectory, among men the T2D IRRs were 0.92 (95 %CI:0.77–1.09) for the second lowest trajectory and 1.51 (95 %CI:0.71–3.20) for the highest trajectory. The corresponding IRRs in women were 0.92 (95 %CI:0.74–1.16) and 3.58 (95 %CI:2.30–5.57). In models including adult BMI, compared to the lowest trajectory, T2D IRRs in men were 0.57 (95 %CI:0.47–0.68) for the second lowest trajectory and 0.26 (95 %CI:0.12–0.56) for the highest trajectory. The corresponding IRRs in women were 0.60 (95 %CI:0.48–0.75) and 0.59 (95 %CI:0.36–0.96). The associations were similar in direction, but not statistically significant, for CHD. Conclusions: Incidence rates of adult-onset T2D were greater for a high child BMI trajectory than a low child BMI trajectory, but not in models that included adult BMI.",
keywords = "Body mass index, Cardiovascular diseases, Diabetes mellitus, Type 2",
author = "Kim Blond and Dorte Vistisen and Julie Aarestrup and Bjerregaard, {Lise G.} and Hudda, {Mohammed T.} and Anne Tj{\o}nneland and Allin, {Kristine H.} and J{\o}rgensen, {Marit E.} and Jensen, {Britt W.} and Baker, {Jennifer L.}",
note = "Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
doi = "10.1016/j.diabres.2022.110055",
language = "English",
volume = "191",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Body mass index trajectories in childhood and incidence rates of type 2 diabetes and coronary heart disease in adulthood

T2 - A cohort study

AU - Blond, Kim

AU - Vistisen, Dorte

AU - Aarestrup, Julie

AU - Bjerregaard, Lise G.

AU - Hudda, Mohammed T.

AU - Tjønneland, Anne

AU - Allin, Kristine H.

AU - Jørgensen, Marit E.

AU - Jensen, Britt W.

AU - Baker, Jennifer L.

N1 - Publisher Copyright: © 2022 The Authors

PY - 2022

Y1 - 2022

N2 - Aims: We examined associations between five body mass index (BMI) trajectories from ages 6–15 years and register-based adult-onset type 2 diabetes mellitus (T2D) and coronary heart disease (CHD) with and without adjustment for adult BMI. Methods: Child and adult BMI came from two Danish cohorts and 13,205 and 13,438 individuals were included in T2D and CHD analyses, respectively. Trajectories were estimated by latent class modelling. Incidence rate ratios (IRRs) were estimated with Poisson regression. Results: In models without adult BMI, compared to the lowest trajectory, among men the T2D IRRs were 0.92 (95 %CI:0.77–1.09) for the second lowest trajectory and 1.51 (95 %CI:0.71–3.20) for the highest trajectory. The corresponding IRRs in women were 0.92 (95 %CI:0.74–1.16) and 3.58 (95 %CI:2.30–5.57). In models including adult BMI, compared to the lowest trajectory, T2D IRRs in men were 0.57 (95 %CI:0.47–0.68) for the second lowest trajectory and 0.26 (95 %CI:0.12–0.56) for the highest trajectory. The corresponding IRRs in women were 0.60 (95 %CI:0.48–0.75) and 0.59 (95 %CI:0.36–0.96). The associations were similar in direction, but not statistically significant, for CHD. Conclusions: Incidence rates of adult-onset T2D were greater for a high child BMI trajectory than a low child BMI trajectory, but not in models that included adult BMI.

AB - Aims: We examined associations between five body mass index (BMI) trajectories from ages 6–15 years and register-based adult-onset type 2 diabetes mellitus (T2D) and coronary heart disease (CHD) with and without adjustment for adult BMI. Methods: Child and adult BMI came from two Danish cohorts and 13,205 and 13,438 individuals were included in T2D and CHD analyses, respectively. Trajectories were estimated by latent class modelling. Incidence rate ratios (IRRs) were estimated with Poisson regression. Results: In models without adult BMI, compared to the lowest trajectory, among men the T2D IRRs were 0.92 (95 %CI:0.77–1.09) for the second lowest trajectory and 1.51 (95 %CI:0.71–3.20) for the highest trajectory. The corresponding IRRs in women were 0.92 (95 %CI:0.74–1.16) and 3.58 (95 %CI:2.30–5.57). In models including adult BMI, compared to the lowest trajectory, T2D IRRs in men were 0.57 (95 %CI:0.47–0.68) for the second lowest trajectory and 0.26 (95 %CI:0.12–0.56) for the highest trajectory. The corresponding IRRs in women were 0.60 (95 %CI:0.48–0.75) and 0.59 (95 %CI:0.36–0.96). The associations were similar in direction, but not statistically significant, for CHD. Conclusions: Incidence rates of adult-onset T2D were greater for a high child BMI trajectory than a low child BMI trajectory, but not in models that included adult BMI.

KW - Body mass index

KW - Cardiovascular diseases

KW - Diabetes mellitus

KW - Type 2

U2 - 10.1016/j.diabres.2022.110055

DO - 10.1016/j.diabres.2022.110055

M3 - Journal article

C2 - 36041552

AN - SCOPUS:85137276134

VL - 191

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

M1 - 110055

ER -

ID: 320654031