Long working hours and cardiovascular disease: a meta-analysis of epidemiologic studies
Research output: Contribution to journal › Journal article › Research › peer-review
OBJECTIVE: To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).
METHODS: Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case-control studies were analyzed for the study.
RESULTS: Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias.
CONCLUSIONS: These findings provide evidence of increased CVD with long working hours.
|Journal||Journal of Occupational and Environmental Medicine|
|Number of pages||6|
|Publication status||Published - 2012|
- Adult, Aged, Cardiovascular Diseases/epidemiology, Confidence Intervals, Female, Humans, Male, Middle Aged, Odds Ratio, Time Factors, Work Schedule Tolerance/physiology, Young Adult