High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test. / Grunnet, Louise Groth; Hjort, Line; Minja, Daniel Thomas; Msemo, Omari Abdul; Møller, Sofie Lykke; Prasad, Rashmi B; Groop, Leif; Lusingu, John; Nielsen, Birgitte Bruun; Schmiegelow, Christentze; Bygbjerg, Ib Christian; Christensen, Dirk Lund.

In: International Journal of Environmental Research and Public Health, Vol. 17, No. 9, 3109, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Grunnet, LG, Hjort, L, Minja, DT, Msemo, OA, Møller, SL, Prasad, RB, Groop, L, Lusingu, J, Nielsen, BB, Schmiegelow, C, Bygbjerg, IC & Christensen, DL 2020, 'High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test', International Journal of Environmental Research and Public Health, vol. 17, no. 9, 3109. https://doi.org/10.3390/ijerph17093109

APA

Grunnet, L. G., Hjort, L., Minja, D. T., Msemo, O. A., Møller, S. L., Prasad, R. B., Groop, L., Lusingu, J., Nielsen, B. B., Schmiegelow, C., Bygbjerg, I. C., & Christensen, D. L. (2020). High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test. International Journal of Environmental Research and Public Health, 17(9), [3109]. https://doi.org/10.3390/ijerph17093109

Vancouver

Grunnet LG, Hjort L, Minja DT, Msemo OA, Møller SL, Prasad RB et al. High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test. International Journal of Environmental Research and Public Health. 2020;17(9). 3109. https://doi.org/10.3390/ijerph17093109

Author

Grunnet, Louise Groth ; Hjort, Line ; Minja, Daniel Thomas ; Msemo, Omari Abdul ; Møller, Sofie Lykke ; Prasad, Rashmi B ; Groop, Leif ; Lusingu, John ; Nielsen, Birgitte Bruun ; Schmiegelow, Christentze ; Bygbjerg, Ib Christian ; Christensen, Dirk Lund. / High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test. In: International Journal of Environmental Research and Public Health. 2020 ; Vol. 17, No. 9.

Bibtex

@article{60d6fce957294dfdad1e68e41464f880,
title = "High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test",
abstract = "Gestational diabetes mellitus (GDM) is associated with poor pregnancy outcomes and increased long-term risk of metabolic diseases for both mother and child. In Tanzania, GDM prevalence increased from 0% in 1991 to 19.5% in 2016. Anaemia has been proposed to precipitate the pathogenesis of GDM. We aimed to examine the prevalence of GDM in a rural area of Tanzania with a high prevalence of anaemia and to examine a potential association between haemoglobin concentration and blood glucose during pregnancy. The participants were included in a population-based preconception, pregnancy and birth cohort study. In total, 538 women were followed during pregnancy and scheduled for an oral glucose tolerance test (OGTT) at week 32-34 of gestation. Gestational diabetes mellitus was diagnosed according to the WHO 2013 guidelines. Out of 392 women screened, 39% (95% CI: 34.2-44.1) had GDM, the majority of whom (94.1%) were diagnosed based solely on the fasting blood sample from the OGTT. No associations were observed between haemoglobin or ferritin and glucose measurements during pregnancy. A very high prevalence of GDM was found in rural Tanzania. In view of the laborious, costly and inconvenient OGTT, alternative methods such as fasting blood glucose should be considered when screening for GDM in low- and middle-income countries.",
author = "Grunnet, {Louise Groth} and Line Hjort and Minja, {Daniel Thomas} and Msemo, {Omari Abdul} and M{\o}ller, {Sofie Lykke} and Prasad, {Rashmi B} and Leif Groop and John Lusingu and Nielsen, {Birgitte Bruun} and Christentze Schmiegelow and Bygbjerg, {Ib Christian} and Christensen, {Dirk Lund}",
year = "2020",
doi = "10.3390/ijerph17093109",
language = "English",
volume = "17",
journal = "International Journal of Environmental Research and Public Health",
issn = "1661-7827",
publisher = "MDPI AG",
number = "9",

}

RIS

TY - JOUR

T1 - High Prevalence of Gestational Diabetes Mellitus in Rural Tanzania-Diagnosis Mainly Based on Fasting Blood Glucose from Oral Glucose Tolerance Test

AU - Grunnet, Louise Groth

AU - Hjort, Line

AU - Minja, Daniel Thomas

AU - Msemo, Omari Abdul

AU - Møller, Sofie Lykke

AU - Prasad, Rashmi B

AU - Groop, Leif

AU - Lusingu, John

AU - Nielsen, Birgitte Bruun

AU - Schmiegelow, Christentze

AU - Bygbjerg, Ib Christian

AU - Christensen, Dirk Lund

PY - 2020

Y1 - 2020

N2 - Gestational diabetes mellitus (GDM) is associated with poor pregnancy outcomes and increased long-term risk of metabolic diseases for both mother and child. In Tanzania, GDM prevalence increased from 0% in 1991 to 19.5% in 2016. Anaemia has been proposed to precipitate the pathogenesis of GDM. We aimed to examine the prevalence of GDM in a rural area of Tanzania with a high prevalence of anaemia and to examine a potential association between haemoglobin concentration and blood glucose during pregnancy. The participants were included in a population-based preconception, pregnancy and birth cohort study. In total, 538 women were followed during pregnancy and scheduled for an oral glucose tolerance test (OGTT) at week 32-34 of gestation. Gestational diabetes mellitus was diagnosed according to the WHO 2013 guidelines. Out of 392 women screened, 39% (95% CI: 34.2-44.1) had GDM, the majority of whom (94.1%) were diagnosed based solely on the fasting blood sample from the OGTT. No associations were observed between haemoglobin or ferritin and glucose measurements during pregnancy. A very high prevalence of GDM was found in rural Tanzania. In view of the laborious, costly and inconvenient OGTT, alternative methods such as fasting blood glucose should be considered when screening for GDM in low- and middle-income countries.

AB - Gestational diabetes mellitus (GDM) is associated with poor pregnancy outcomes and increased long-term risk of metabolic diseases for both mother and child. In Tanzania, GDM prevalence increased from 0% in 1991 to 19.5% in 2016. Anaemia has been proposed to precipitate the pathogenesis of GDM. We aimed to examine the prevalence of GDM in a rural area of Tanzania with a high prevalence of anaemia and to examine a potential association between haemoglobin concentration and blood glucose during pregnancy. The participants were included in a population-based preconception, pregnancy and birth cohort study. In total, 538 women were followed during pregnancy and scheduled for an oral glucose tolerance test (OGTT) at week 32-34 of gestation. Gestational diabetes mellitus was diagnosed according to the WHO 2013 guidelines. Out of 392 women screened, 39% (95% CI: 34.2-44.1) had GDM, the majority of whom (94.1%) were diagnosed based solely on the fasting blood sample from the OGTT. No associations were observed between haemoglobin or ferritin and glucose measurements during pregnancy. A very high prevalence of GDM was found in rural Tanzania. In view of the laborious, costly and inconvenient OGTT, alternative methods such as fasting blood glucose should be considered when screening for GDM in low- and middle-income countries.

U2 - 10.3390/ijerph17093109

DO - 10.3390/ijerph17093109

M3 - Journal article

C2 - 32365670

VL - 17

JO - International Journal of Environmental Research and Public Health

JF - International Journal of Environmental Research and Public Health

SN - 1661-7827

IS - 9

M1 - 3109

ER -

ID: 240742441