Despite numerous efforts to prevent work-related illnesses and health-promoting measures in the work environment, an increased number of employees find themselves mentally stressed, and work-related musculoskeletal problems are still common. To overcome these problems, new methods have been developed integrating preventive and health-promotion efforts in the work environment with a clear organisational foundation. Recent research has shown good results from these integrated approaches as shown in this review, and this may be the key to create a work environment, which may even improve the health of employees.