Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project

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Standard

Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort : the ELAPSE project. / Chen, Jie; Rodopoulou, Sophia; Strak, Maciej; de Hoogh, Kees; Taj, Tahir; Poulsen, Aslak Harbo; Andersen, Zorana J.; Bellander, Tom; Brandt, Jorgen; Zitt, Emanuel; Fecht, Daniela; Forastiere, Francesco; Gulliver, John; Hertel, Ole; Hoffmann, Barbara; Hvidtfeldt, Ulla Arthur; Verschuren, W. M. Monique; Jorgensen, Jeanette T.; Katsouyanni, Klea; Ketzel, Matthias; Lager, Anton; Leander, Karin; Liu, Shuo; Ljungman, Petter; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Magnusson, Patrik K. E.; Nagel, Gabriele; Pershagen, Goran; Peters, Annette; Rizzuto, Debora; van der Schouw, Yvonne T.; Samoli, Evangelia; Sørensen, Mette; Stafoggia, Massimo; Tjønneland, Anne; Weinmayr, Gudrun; Wolf, Kathrin; Brunekreef, Bert; Raaschou-Nielsen, Ole; Hoek, Gerard.

In: British Journal of Cancer, Vol. 126, 2022, p. 1499–1507.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Chen, J, Rodopoulou, S, Strak, M, de Hoogh, K, Taj, T, Poulsen, AH, Andersen, ZJ, Bellander, T, Brandt, J, Zitt, E, Fecht, D, Forastiere, F, Gulliver, J, Hertel, O, Hoffmann, B, Hvidtfeldt, UA, Verschuren, WMM, Jorgensen, JT, Katsouyanni, K, Ketzel, M, Lager, A, Leander, K, Liu, S, Ljungman, P, Severi, G, Boutron-Ruault, M-C, Magnusson, PKE, Nagel, G, Pershagen, G, Peters, A, Rizzuto, D, van der Schouw, YT, Samoli, E, Sørensen, M, Stafoggia, M, Tjønneland, A, Weinmayr, G, Wolf, K, Brunekreef, B, Raaschou-Nielsen, O & Hoek, G 2022, 'Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project', British Journal of Cancer, vol. 126, pp. 1499–1507. https://doi.org/10.1038/s41416-022-01735-4

APA

Chen, J., Rodopoulou, S., Strak, M., de Hoogh, K., Taj, T., Poulsen, A. H., Andersen, Z. J., Bellander, T., Brandt, J., Zitt, E., Fecht, D., Forastiere, F., Gulliver, J., Hertel, O., Hoffmann, B., Hvidtfeldt, U. A., Verschuren, W. M. M., Jorgensen, J. T., Katsouyanni, K., ... Hoek, G. (2022). Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project. British Journal of Cancer, 126, 1499–1507. https://doi.org/10.1038/s41416-022-01735-4

Vancouver

Chen J, Rodopoulou S, Strak M, de Hoogh K, Taj T, Poulsen AH et al. Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project. British Journal of Cancer. 2022;126:1499–1507. https://doi.org/10.1038/s41416-022-01735-4

Author

Chen, Jie ; Rodopoulou, Sophia ; Strak, Maciej ; de Hoogh, Kees ; Taj, Tahir ; Poulsen, Aslak Harbo ; Andersen, Zorana J. ; Bellander, Tom ; Brandt, Jorgen ; Zitt, Emanuel ; Fecht, Daniela ; Forastiere, Francesco ; Gulliver, John ; Hertel, Ole ; Hoffmann, Barbara ; Hvidtfeldt, Ulla Arthur ; Verschuren, W. M. Monique ; Jorgensen, Jeanette T. ; Katsouyanni, Klea ; Ketzel, Matthias ; Lager, Anton ; Leander, Karin ; Liu, Shuo ; Ljungman, Petter ; Severi, Gianluca ; Boutron-Ruault, Marie-Christine ; Magnusson, Patrik K. E. ; Nagel, Gabriele ; Pershagen, Goran ; Peters, Annette ; Rizzuto, Debora ; van der Schouw, Yvonne T. ; Samoli, Evangelia ; Sørensen, Mette ; Stafoggia, Massimo ; Tjønneland, Anne ; Weinmayr, Gudrun ; Wolf, Kathrin ; Brunekreef, Bert ; Raaschou-Nielsen, Ole ; Hoek, Gerard. / Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort : the ELAPSE project. In: British Journal of Cancer. 2022 ; Vol. 126. pp. 1499–1507.

Bibtex

@article{cde0fc5c6ac24d3fa36e1c9789af7f2c,
title = "Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project",
abstract = "BACKGROUND: The evidence linking ambient air pollution to bladder cancer is limited and mixed.METHODS: We assessed the associations of bladder cancer incidence with residential exposure to fine particles (PM2.5), nitrogen dioxide (NO2), black carbon (BC), warm season ozone (O-3) and eight PM2.5 elemental components (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in a pooled cohort (N = 302,493). Exposures were primarily assessed based on 2010 measurements and back-extrapolated to the baseline years. We applied Cox proportional hazard models adjusting for individual- and area-level potential confounders.RESULTS: During an average of 18.2 years follow-up, 967 bladder cancer cases occurred. We observed a positive though statistically non-significant association between PM2.5 and bladder cancer incidence. Hazard Ratios (HR) were 1.09 (95% confidence interval (CI): 0.93-1.27) per 5 mu g/m(3) for 2010 exposure and 1.06 (95% CI: 0.99-1.14) for baseline exposure. Effect estimates for NO2, BC and O-3 were close to unity. A positive association was observed with PM2.5 zinc (HR 1.08; 95% CI: 1.00-1.16 per 10 ng/m(3)).CONCLUSIONS: We found suggestive evidence of an association between long-term PM2.5 mass exposure and bladder cancer, strengthening the evidence from the few previous studies. The association with zinc in PM2.5 suggests the importance of industrial emissions.",
keywords = "USE REGRESSION-MODELS, MEN, MORTALITY, RISK, POPULATION, PROFILE, DIESEL, NO2, CARCINOGENICITY, COMPONENTS",
author = "Jie Chen and Sophia Rodopoulou and Maciej Strak and {de Hoogh}, Kees and Tahir Taj and Poulsen, {Aslak Harbo} and Andersen, {Zorana J.} and Tom Bellander and Jorgen Brandt and Emanuel Zitt and Daniela Fecht and Francesco Forastiere and John Gulliver and Ole Hertel and Barbara Hoffmann and Hvidtfeldt, {Ulla Arthur} and Verschuren, {W. M. Monique} and Jorgensen, {Jeanette T.} and Klea Katsouyanni and Matthias Ketzel and Anton Lager and Karin Leander and Shuo Liu and Petter Ljungman and Gianluca Severi and Marie-Christine Boutron-Ruault and Magnusson, {Patrik K. E.} and Gabriele Nagel and Goran Pershagen and Annette Peters and Debora Rizzuto and {van der Schouw}, {Yvonne T.} and Evangelia Samoli and Mette S{\o}rensen and Massimo Stafoggia and Anne Tj{\o}nneland and Gudrun Weinmayr and Kathrin Wolf and Bert Brunekreef and Ole Raaschou-Nielsen and Gerard Hoek",
year = "2022",
doi = "10.1038/s41416-022-01735-4",
language = "English",
volume = "126",
pages = "1499–1507",
journal = "The British journal of cancer. Supplement",
issn = "0007-0920",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort

T2 - the ELAPSE project

AU - Chen, Jie

AU - Rodopoulou, Sophia

AU - Strak, Maciej

AU - de Hoogh, Kees

AU - Taj, Tahir

AU - Poulsen, Aslak Harbo

AU - Andersen, Zorana J.

AU - Bellander, Tom

AU - Brandt, Jorgen

AU - Zitt, Emanuel

AU - Fecht, Daniela

AU - Forastiere, Francesco

AU - Gulliver, John

AU - Hertel, Ole

AU - Hoffmann, Barbara

AU - Hvidtfeldt, Ulla Arthur

AU - Verschuren, W. M. Monique

AU - Jorgensen, Jeanette T.

AU - Katsouyanni, Klea

AU - Ketzel, Matthias

AU - Lager, Anton

AU - Leander, Karin

AU - Liu, Shuo

AU - Ljungman, Petter

AU - Severi, Gianluca

AU - Boutron-Ruault, Marie-Christine

AU - Magnusson, Patrik K. E.

AU - Nagel, Gabriele

AU - Pershagen, Goran

AU - Peters, Annette

AU - Rizzuto, Debora

AU - van der Schouw, Yvonne T.

AU - Samoli, Evangelia

AU - Sørensen, Mette

AU - Stafoggia, Massimo

AU - Tjønneland, Anne

AU - Weinmayr, Gudrun

AU - Wolf, Kathrin

AU - Brunekreef, Bert

AU - Raaschou-Nielsen, Ole

AU - Hoek, Gerard

PY - 2022

Y1 - 2022

N2 - BACKGROUND: The evidence linking ambient air pollution to bladder cancer is limited and mixed.METHODS: We assessed the associations of bladder cancer incidence with residential exposure to fine particles (PM2.5), nitrogen dioxide (NO2), black carbon (BC), warm season ozone (O-3) and eight PM2.5 elemental components (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in a pooled cohort (N = 302,493). Exposures were primarily assessed based on 2010 measurements and back-extrapolated to the baseline years. We applied Cox proportional hazard models adjusting for individual- and area-level potential confounders.RESULTS: During an average of 18.2 years follow-up, 967 bladder cancer cases occurred. We observed a positive though statistically non-significant association between PM2.5 and bladder cancer incidence. Hazard Ratios (HR) were 1.09 (95% confidence interval (CI): 0.93-1.27) per 5 mu g/m(3) for 2010 exposure and 1.06 (95% CI: 0.99-1.14) for baseline exposure. Effect estimates for NO2, BC and O-3 were close to unity. A positive association was observed with PM2.5 zinc (HR 1.08; 95% CI: 1.00-1.16 per 10 ng/m(3)).CONCLUSIONS: We found suggestive evidence of an association between long-term PM2.5 mass exposure and bladder cancer, strengthening the evidence from the few previous studies. The association with zinc in PM2.5 suggests the importance of industrial emissions.

AB - BACKGROUND: The evidence linking ambient air pollution to bladder cancer is limited and mixed.METHODS: We assessed the associations of bladder cancer incidence with residential exposure to fine particles (PM2.5), nitrogen dioxide (NO2), black carbon (BC), warm season ozone (O-3) and eight PM2.5 elemental components (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in a pooled cohort (N = 302,493). Exposures were primarily assessed based on 2010 measurements and back-extrapolated to the baseline years. We applied Cox proportional hazard models adjusting for individual- and area-level potential confounders.RESULTS: During an average of 18.2 years follow-up, 967 bladder cancer cases occurred. We observed a positive though statistically non-significant association between PM2.5 and bladder cancer incidence. Hazard Ratios (HR) were 1.09 (95% confidence interval (CI): 0.93-1.27) per 5 mu g/m(3) for 2010 exposure and 1.06 (95% CI: 0.99-1.14) for baseline exposure. Effect estimates for NO2, BC and O-3 were close to unity. A positive association was observed with PM2.5 zinc (HR 1.08; 95% CI: 1.00-1.16 per 10 ng/m(3)).CONCLUSIONS: We found suggestive evidence of an association between long-term PM2.5 mass exposure and bladder cancer, strengthening the evidence from the few previous studies. The association with zinc in PM2.5 suggests the importance of industrial emissions.

KW - USE REGRESSION-MODELS

KW - MEN

KW - MORTALITY

KW - RISK

KW - POPULATION

KW - PROFILE

KW - DIESEL

KW - NO2

KW - CARCINOGENICITY

KW - COMPONENTS

U2 - 10.1038/s41416-022-01735-4

DO - 10.1038/s41416-022-01735-4

M3 - Journal article

C2 - 35173304

VL - 126

SP - 1499

EP - 1507

JO - The British journal of cancer. Supplement

JF - The British journal of cancer. Supplement

SN - 0007-0920

ER -

ID: 299391536