Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene? / Rudolph, S.S.; Jehu, G.; Nielsen, S.L.; Nielsen, K.; Siersma, Volkert Dirk; Rasmussen, L.S.

In: Resuscitation, Vol. 82, No. 11, 2011, p. 1414-1418.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Rudolph, SS, Jehu, G, Nielsen, SL, Nielsen, K, Siersma, VD & Rasmussen, LS 2011, 'Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene?', Resuscitation, vol. 82, no. 11, pp. 1414-1418. https://doi.org/10.1016/j.resuscitation.2011.06.027

APA

Rudolph, S. S., Jehu, G., Nielsen, S. L., Nielsen, K., Siersma, V. D., & Rasmussen, L. S. (2011). Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene? Resuscitation, 82(11), 1414-1418. https://doi.org/10.1016/j.resuscitation.2011.06.027

Vancouver

Rudolph SS, Jehu G, Nielsen SL, Nielsen K, Siersma VD, Rasmussen LS. Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene? Resuscitation. 2011;82(11):1414-1418. https://doi.org/10.1016/j.resuscitation.2011.06.027

Author

Rudolph, S.S. ; Jehu, G. ; Nielsen, S.L. ; Nielsen, K. ; Siersma, Volkert Dirk ; Rasmussen, L.S. / Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene?. In: Resuscitation. 2011 ; Vol. 82, No. 11. pp. 1414-1418.

Bibtex

@article{6ccf760e90214cca9af64c1a0ce58687,
title = "Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene?",
abstract = "INTRODUCTION: In the prehospital setting opioid overdose is often treated with naloxone. In our physician-based medical emergency care unit (MECU) we have adopted a discharge-on-scene policy, where patients are released on scene if no residual signs of opioid intoxication are found after treatment. The aim of this study was to describe our experience with the discharge-on-scene policy used during a 10-year-period with focus on the frequency of rebound opioid toxicity. METHODS: Data were prospectively recorded in our MECU database and we reviewed all cases of opioid overdose between 1994 and 2003. The MECU database was cross-referenced with the Central Personal Registry. For patients who died within 48 h of MECU contact we reviewed the forensic autopsy reports to establish whether rebound opioid toxicity was likely. RESULTS: We found 4762 cases of acute opioid overdose. In 3245 cases positive identification was obtained. Over this ten year period fourteen patients who were released on-scene after having been treated with naloxone died within 48 h, but only in 3 of these we found a rebound opioid toxicity to be the likely cause of death, corresponding to 0.13% of those 2241 released on scene who were identified. CONCLUSION: Prehospital discharge-on-scene after naloxone treatment is associated with a low risk of death due to rebound toxicity",
keywords = "care, Cause of Death, Denmark, methods, Naloxone, Overdose, PATIENT, Patients, Registries, Risk",
author = "S.S. Rudolph and G. Jehu and S.L. Nielsen and K. Nielsen and Siersma, {Volkert Dirk} and L.S. Rasmussen",
note = "Copyright {\textcopyright} 2011 Elsevier Ireland Ltd. All rights reserved.",
year = "2011",
doi = "http://dx.doi.org/10.1016/j.resuscitation.2011.06.027",
language = "English",
volume = "82",
pages = "1414--1418",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",
number = "11",

}

RIS

TY - JOUR

T1 - Prehospital treatment of opioid overdose in Copenhagen--is it safe to discharge on-scene?

AU - Rudolph, S.S.

AU - Jehu, G.

AU - Nielsen, S.L.

AU - Nielsen, K.

AU - Siersma, Volkert Dirk

AU - Rasmussen, L.S.

N1 - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

PY - 2011

Y1 - 2011

N2 - INTRODUCTION: In the prehospital setting opioid overdose is often treated with naloxone. In our physician-based medical emergency care unit (MECU) we have adopted a discharge-on-scene policy, where patients are released on scene if no residual signs of opioid intoxication are found after treatment. The aim of this study was to describe our experience with the discharge-on-scene policy used during a 10-year-period with focus on the frequency of rebound opioid toxicity. METHODS: Data were prospectively recorded in our MECU database and we reviewed all cases of opioid overdose between 1994 and 2003. The MECU database was cross-referenced with the Central Personal Registry. For patients who died within 48 h of MECU contact we reviewed the forensic autopsy reports to establish whether rebound opioid toxicity was likely. RESULTS: We found 4762 cases of acute opioid overdose. In 3245 cases positive identification was obtained. Over this ten year period fourteen patients who were released on-scene after having been treated with naloxone died within 48 h, but only in 3 of these we found a rebound opioid toxicity to be the likely cause of death, corresponding to 0.13% of those 2241 released on scene who were identified. CONCLUSION: Prehospital discharge-on-scene after naloxone treatment is associated with a low risk of death due to rebound toxicity

AB - INTRODUCTION: In the prehospital setting opioid overdose is often treated with naloxone. In our physician-based medical emergency care unit (MECU) we have adopted a discharge-on-scene policy, where patients are released on scene if no residual signs of opioid intoxication are found after treatment. The aim of this study was to describe our experience with the discharge-on-scene policy used during a 10-year-period with focus on the frequency of rebound opioid toxicity. METHODS: Data were prospectively recorded in our MECU database and we reviewed all cases of opioid overdose between 1994 and 2003. The MECU database was cross-referenced with the Central Personal Registry. For patients who died within 48 h of MECU contact we reviewed the forensic autopsy reports to establish whether rebound opioid toxicity was likely. RESULTS: We found 4762 cases of acute opioid overdose. In 3245 cases positive identification was obtained. Over this ten year period fourteen patients who were released on-scene after having been treated with naloxone died within 48 h, but only in 3 of these we found a rebound opioid toxicity to be the likely cause of death, corresponding to 0.13% of those 2241 released on scene who were identified. CONCLUSION: Prehospital discharge-on-scene after naloxone treatment is associated with a low risk of death due to rebound toxicity

KW - care

KW - Cause of Death

KW - Denmark

KW - methods

KW - Naloxone

KW - Overdose

KW - PATIENT

KW - Patients

KW - Registries

KW - Risk

U2 - http://dx.doi.org/10.1016/j.resuscitation.2011.06.027

DO - http://dx.doi.org/10.1016/j.resuscitation.2011.06.027

M3 - Journal article

VL - 82

SP - 1414

EP - 1418

JO - Resuscitation

JF - Resuscitation

SN - 0300-9572

IS - 11

ER -

ID: 37581381