Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts

Research output: Contribution to journalJournal articleResearchpeer-review

Lise Aksglaede, Anna-Maria Andersson, Niels Jørgensen, Tina Kold Jensen, Elisabeth Carlsen, Robert I McLachlan, Niels E Skakkebaek, Jørgen Holm Petersen, Anders Juul

The diagnosis of androgen deficiency is based on clinical features and confirmatory low serum testosterone levels. In early primary testicular failure, a rise in serum LH levels suggests inadequate androgen action for the individual's physiological requirements despite a serum testosterone level within the normal range. The combined evaluation of serum LH and testosterone levels in the evaluation of testicular failure has not been widely advocated.
Original languageEnglish
JournalClinical Endocrinology
Volume66
Issue number2
Pages (from-to)276-81
Number of pages6
ISSN0300-0664
DOIs
Publication statusPublished - 1 Feb 2007

ID: 4031960