Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment

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Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment. / Juul, A; Müller, J; Skakkebaek, N E.

In: European Journal of Endocrinology, Vol. 136, No. 4, 1997, p. 401-5.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Juul, A, Müller, J & Skakkebaek, NE 1997, 'Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment', European Journal of Endocrinology, vol. 136, no. 4, pp. 401-5.

APA

Juul, A., Müller, J., & Skakkebaek, N. E. (1997). Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment. European Journal of Endocrinology, 136(4), 401-5.

Vancouver

Juul A, Müller J, Skakkebaek NE. Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment. European Journal of Endocrinology. 1997;136(4):401-5.

Author

Juul, A ; Müller, J ; Skakkebaek, N E. / Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment. In: European Journal of Endocrinology. 1997 ; Vol. 136, No. 4. pp. 401-5.

Bibtex

@article{638bd1e651594a05aa71437c4ba6291c,
title = "Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment",
abstract = "In healthy boys, the pituitary-gonadal axis exhibits diurnal variation in early puberty. Serum testosterone levels are higher during the night and low or immeasurable during the day. These fluctuating levels of circulating androgens in early pubertal boys are difficult to monitor. Prostate specific antigen (PSA) is a marker of the androgen-dependent prostatic epithelial cell activity and it is used in the diagnosis and surveillance of adult patients with prostatic cancer. We have measured PSA concentrations in serum from boys with precocious puberty before and during gonadal suppression with GnRH agonists to evaluate the effect of normal and precocious puberty on PSA levels and to study the correlation between testosterone and PSA in boys.",
author = "A Juul and J M{\"u}ller and Skakkebaek, {N E}",
year = "1997",
language = "English",
volume = "136",
pages = "401--5",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment

AU - Juul, A

AU - Müller, J

AU - Skakkebaek, N E

PY - 1997

Y1 - 1997

N2 - In healthy boys, the pituitary-gonadal axis exhibits diurnal variation in early puberty. Serum testosterone levels are higher during the night and low or immeasurable during the day. These fluctuating levels of circulating androgens in early pubertal boys are difficult to monitor. Prostate specific antigen (PSA) is a marker of the androgen-dependent prostatic epithelial cell activity and it is used in the diagnosis and surveillance of adult patients with prostatic cancer. We have measured PSA concentrations in serum from boys with precocious puberty before and during gonadal suppression with GnRH agonists to evaluate the effect of normal and precocious puberty on PSA levels and to study the correlation between testosterone and PSA in boys.

AB - In healthy boys, the pituitary-gonadal axis exhibits diurnal variation in early puberty. Serum testosterone levels are higher during the night and low or immeasurable during the day. These fluctuating levels of circulating androgens in early pubertal boys are difficult to monitor. Prostate specific antigen (PSA) is a marker of the androgen-dependent prostatic epithelial cell activity and it is used in the diagnosis and surveillance of adult patients with prostatic cancer. We have measured PSA concentrations in serum from boys with precocious puberty before and during gonadal suppression with GnRH agonists to evaluate the effect of normal and precocious puberty on PSA levels and to study the correlation between testosterone and PSA in boys.

M3 - Journal article

VL - 136

SP - 401

EP - 405

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 4

ER -

ID: 48486494