Risk of depressive disorder following disasters and military deployment: systematic review with meta-analysis
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Risk of depressive disorder following disasters and military deployment : systematic review with meta-analysis. / Bonde, J. P.; Utzon-Frank, Nicolai; Bertelsen, M.; Borritz, M.; Eller, N. H.; Nordentoft, M.; Olesen, K.; Rod, N. H.; Rugulies, R.
In: The British journal of psychiatry : the journal of mental science, Vol. 208, No. 4, 04.2016, p. 330-336.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Risk of depressive disorder following disasters and military deployment
T2 - systematic review with meta-analysis
AU - Bonde, J. P.
AU - Utzon-Frank, Nicolai
AU - Bertelsen, M.
AU - Borritz, M.
AU - Eller, N. H.
AU - Nordentoft, M.
AU - Olesen, K.
AU - Rod, N. H.
AU - Rugulies, R.
N1 - © The Royal College of Psychiatrists 2016.
PY - 2016/4
Y1 - 2016/4
N2 - BACKGROUND: Numerous studies describe the occurrence of post-traumatic stress disorder following disasters, but less is known about the risk of major depression.AIMS: To review the risk of depressive disorder in people surviving disasters and in soldiers returning from military deployment.METHOD: A systematic literature search combined with reference screening identified 23 controlled epidemiological studies. We used random effects models to compute pooled odds ratios (ORs).RESULTS: The average OR was significantly elevated following all types of exposures: natural disaster OR = 2.28 (95% CI 1.30-3.98), technological disaster OR = 1.44 (95% CI 1.21-1.70), terrorist acts OR = 1.80 (95% CI 1.38-2.34) and military combat OR = 1.60 (95% CI 1.09-2.35). In a subset of ten high-quality studies OR was 1.41 (95% CI 1.06-1.87).CONCLUSIONS: Disasters and combat experience substantially increase the risk of depression. Whether psychological trauma per se or bereavement is on the causal path is unresolved.
AB - BACKGROUND: Numerous studies describe the occurrence of post-traumatic stress disorder following disasters, but less is known about the risk of major depression.AIMS: To review the risk of depressive disorder in people surviving disasters and in soldiers returning from military deployment.METHOD: A systematic literature search combined with reference screening identified 23 controlled epidemiological studies. We used random effects models to compute pooled odds ratios (ORs).RESULTS: The average OR was significantly elevated following all types of exposures: natural disaster OR = 2.28 (95% CI 1.30-3.98), technological disaster OR = 1.44 (95% CI 1.21-1.70), terrorist acts OR = 1.80 (95% CI 1.38-2.34) and military combat OR = 1.60 (95% CI 1.09-2.35). In a subset of ten high-quality studies OR was 1.41 (95% CI 1.06-1.87).CONCLUSIONS: Disasters and combat experience substantially increase the risk of depression. Whether psychological trauma per se or bereavement is on the causal path is unresolved.
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
KW - Review
U2 - 10.1192/bjp.bp.114.157859
DO - 10.1192/bjp.bp.114.157859
M3 - Review
C2 - 26892850
VL - 208
SP - 330
EP - 336
JO - The Journal of mental science
JF - The Journal of mental science
SN - 0960-5371
IS - 4
ER -
ID: 166169947