SARS-CoV-2 infection causes COVID-19. Most infected children have asymptomatic or mild clinical manifestations. A few develop serious illness, and the case fatality rate is lower than in adults. The most frequent symptoms are fever and cough. Studies indicate that children might be less susceptible to infection than adults as summarised in this review. Despite mild manifestation, some children experience a hyper-inflammatory response to SARS-CoV-2 infection called multisystem inflammatory syndrome, similarly to Kawasaki disease. The syndrome is still very rare, and the pathogenesis remains unknown.