Severe mortality impact of the 1957 influenza pandemic in Chile

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Severe mortality impact of the 1957 influenza pandemic in Chile. / Chowell, Gerardo; Simonsen, Lone; Fuentes, Rodrigo; Flores, Jose; Miller, Mark A.; Viboud, Cécile.

In: Influenza and Other Respiratory Viruses, Vol. 11, No. 3, 05.2017, p. 230–239.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Chowell, G, Simonsen, L, Fuentes, R, Flores, J, Miller, MA & Viboud, C 2017, 'Severe mortality impact of the 1957 influenza pandemic in Chile', Influenza and Other Respiratory Viruses, vol. 11, no. 3, pp. 230–239. https://doi.org/10.1111/irv.12439

APA

Chowell, G., Simonsen, L., Fuentes, R., Flores, J., Miller, M. A., & Viboud, C. (2017). Severe mortality impact of the 1957 influenza pandemic in Chile. Influenza and Other Respiratory Viruses, 11(3), 230–239. https://doi.org/10.1111/irv.12439

Vancouver

Chowell G, Simonsen L, Fuentes R, Flores J, Miller MA, Viboud C. Severe mortality impact of the 1957 influenza pandemic in Chile. Influenza and Other Respiratory Viruses. 2017 May;11(3):230–239. https://doi.org/10.1111/irv.12439

Author

Chowell, Gerardo ; Simonsen, Lone ; Fuentes, Rodrigo ; Flores, Jose ; Miller, Mark A. ; Viboud, Cécile. / Severe mortality impact of the 1957 influenza pandemic in Chile. In: Influenza and Other Respiratory Viruses. 2017 ; Vol. 11, No. 3. pp. 230–239.

Bibtex

@article{ed3f1aae8918457eba985c013295f9d4,
title = "Severe mortality impact of the 1957 influenza pandemic in Chile",
abstract = "INTRODUCTION: Epidemiological studies of the 1957 influenza pandemic are scarce, particularly from lower income settings.METHODS: We analyzed the spatial-temporal mortality patterns of the 1957 influenza pandemic in Chile including detailed age-specific mortality data from a large city and investigated risk factors for severe mortality impact across regions.RESULTS: Chile exhibited two waves of excess mortality in winter 1957 and 1959 with a cumulative excess mortality rate of 12 per 10,000, and a ~10-fold mortality difference across provinces. High excess-mortality rates were associated with high baseline mortality (R2=41.8%; P=0.02), but not with latitude (P>0.7). Excess mortality rates increased sharply with age. Transmissibility declined from R=1.4-2.1 to R=1.2-1.4 between the two pandemic waves.CONCLUSIONS: The estimated A/H2N2 mortality burden in Chile is the highest on record for this pandemic - about 3-5 times as severe as that experienced in wealthier nations. The global impact of this pandemic may be substantially underestimated from previous studies based on high-income countries.",
author = "Gerardo Chowell and Lone Simonsen and Rodrigo Fuentes and Jose Flores and Miller, {Mark A.} and C{\'e}cile Viboud",
note = "This article is protected by copyright. All rights reserved.",
year = "2017",
month = may,
doi = "10.1111/irv.12439",
language = "English",
volume = "11",
pages = "230–239",
journal = "Influenza and other Respiratory Viruses",
issn = "1750-2640",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Severe mortality impact of the 1957 influenza pandemic in Chile

AU - Chowell, Gerardo

AU - Simonsen, Lone

AU - Fuentes, Rodrigo

AU - Flores, Jose

AU - Miller, Mark A.

AU - Viboud, Cécile

N1 - This article is protected by copyright. All rights reserved.

PY - 2017/5

Y1 - 2017/5

N2 - INTRODUCTION: Epidemiological studies of the 1957 influenza pandemic are scarce, particularly from lower income settings.METHODS: We analyzed the spatial-temporal mortality patterns of the 1957 influenza pandemic in Chile including detailed age-specific mortality data from a large city and investigated risk factors for severe mortality impact across regions.RESULTS: Chile exhibited two waves of excess mortality in winter 1957 and 1959 with a cumulative excess mortality rate of 12 per 10,000, and a ~10-fold mortality difference across provinces. High excess-mortality rates were associated with high baseline mortality (R2=41.8%; P=0.02), but not with latitude (P>0.7). Excess mortality rates increased sharply with age. Transmissibility declined from R=1.4-2.1 to R=1.2-1.4 between the two pandemic waves.CONCLUSIONS: The estimated A/H2N2 mortality burden in Chile is the highest on record for this pandemic - about 3-5 times as severe as that experienced in wealthier nations. The global impact of this pandemic may be substantially underestimated from previous studies based on high-income countries.

AB - INTRODUCTION: Epidemiological studies of the 1957 influenza pandemic are scarce, particularly from lower income settings.METHODS: We analyzed the spatial-temporal mortality patterns of the 1957 influenza pandemic in Chile including detailed age-specific mortality data from a large city and investigated risk factors for severe mortality impact across regions.RESULTS: Chile exhibited two waves of excess mortality in winter 1957 and 1959 with a cumulative excess mortality rate of 12 per 10,000, and a ~10-fold mortality difference across provinces. High excess-mortality rates were associated with high baseline mortality (R2=41.8%; P=0.02), but not with latitude (P>0.7). Excess mortality rates increased sharply with age. Transmissibility declined from R=1.4-2.1 to R=1.2-1.4 between the two pandemic waves.CONCLUSIONS: The estimated A/H2N2 mortality burden in Chile is the highest on record for this pandemic - about 3-5 times as severe as that experienced in wealthier nations. The global impact of this pandemic may be substantially underestimated from previous studies based on high-income countries.

U2 - 10.1111/irv.12439

DO - 10.1111/irv.12439

M3 - Journal article

C2 - 27883281

VL - 11

SP - 230

EP - 239

JO - Influenza and other Respiratory Viruses

JF - Influenza and other Respiratory Viruses

SN - 1750-2640

IS - 3

ER -

ID: 171796111