Gitta Wörtwein
Associate Professor
Section of Environmental Health
Øster Farimagsgade 5, 1014 København K, 05 Øster Farimagsgade 5, Building: 05-1-08
Member of:
- 1993
- Published
Retention and relearning of spatial delayed alternation in rats after combined or sequential lesions of the prefrontal and parietal cortex
Wörtwein, Gitta, Mogensen, J. & Divac, I., 1993, In: Acta Neurobiologiae Experimentalis. 53, p. 357-366Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Cortical area in the rat that mediates visual pattern discrimination
Wörtwein, Gitta, Mogensen, J., Williams, G., Carlos, J. H. & Divac, I., 1994, In: Acta Neurobiologiae Experimentalis. 54, p. 365-376Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retention and relearning of spatial delayed alternation in rats after ablation of the prefrontal or total non-prefrontal isocortex
Wörtwein, Gitta, Mogensen, J. & Divac, I., 1994, In: Behavioural Brain Research. 63, p. 127-131Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Functional and neurochemical profile of place learning after L-nitro-arginine in the rat
Mogensen, J., Wörtwein, Gitta, Hasman, A., Nielsen, P. & Wang, Q., 1995, In: Neurobiology of Learning and Memory. 63, p. 54-65Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-Nitroarginine reduces hippocampal mediation of place learning in the rat
Mogensen, J., Wörtwein, Gitta, Gustafson, B. & Ermens, P., 1995, In: Neurobiology of Learning and Memory. 64, p. 17-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Place learning during inhibition of nitric oxide synthase in the rat
Mogensen, J., Hasman, A. & Wörtwein, Gitta, 1995, In: Homeostasis. 36, p. 12-18Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Place learning by fimbria-fornix transected rats in a modified water maze
Wörtwein, Gitta, Særup, L. H., Charlottenfeld-Starpov, D. & Mogensen, J., 1995, In: International Journal of Neuroscience. 82, p. 71-81Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Cholinergic control of nerve growth factor in adult rats: evidence from cortical cholinergic deafferentation and chronic drug treatment
Rossner, S., Wörtwein, Gitta, Gu, Z., Yu, J., Schliebs, R., Bigl, V. & Perez-Polo, J., 1998, In: Journal of Neurochemistry. Vol. 69, p. 947-953Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Responses of young and aged rat CNS to partial cholinergic immunolesions and NGF treatment
Wörtwein, Gitta, Yu, J., Toliver-Kinsky, T. & Perez-Polo, J., 1998, In: Journal of Neuroscience Research. Vol. 52, p. 322-333Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Dyremodeller i neuropsykiatrisk forskning
Mogensen, J. & Wörtwein, Gitta, 1999, Neuropsykiatriske Aspekter. Danmark, p. 116-123Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- 2000
- Published
Model for aging inthe basal forebrain cholinergic system
Wörtwein, Gitta, Gu, Z., Yu, J. & Perez-Polo, J. R., 2000, In: Antioxidants & Redox Signaling. 2,3, p. 437-447Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Place learning in scolopamine-treated rats: the role of distal cues and catecholaminergic mediation
Mogensen, J., Christensen, L. H., Johansson, A., Wörtwein, Gitta, Bang, L. E. & Holm, S., 2002, In: Neurobiology of Learning and Memory. 78(1), p. 139-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of epibatidine binding to medial habenula: potential role in analgesia
Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2002, In: Journal of Pharmacology and Experimental Therapeutics. vol. 302, p. 759-65Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain
Altar, C. A., Whitehead, R. E., Chen, R., Wörtwein, Gitta & Madsen, T. M., 2003, In: Biological Psychiatry. VOl. 54, no. 7, p. 703-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role for M5 muscarinic acetylcholine receptors in cocaine addiction
Fink-Jensen, A., Fedorova, I., Wörtwein, Gitta, Woldbye, David Paul Drucker, Rasmussen, T., Thomsen, M., Bolwig, T. G., Knitowski, K. M., McKinzie, D. L., Yamada, M., Wess, J. & Basile, A., 2003, In: Journal of Neuroscience Research. 74, 1, p. 91-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat
Madsen, T. M., Kristjansen, P. E. G., Bolwig, T. G. & Wörtwein, Gitta, 2003, In: Neuroscience. Vol. 119, p. 635-42Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of response patterns during prefrontally ablated rats acquisition of an egocentric spatial task in an 8-arm radialmaze
Mogensen, J., Montero, A. & Wörtwein, Gitta, 2003, In: Homeostasis. Vol. 42, no.1-2, p. 52-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associative an nonassociative learning after chronic imipramine in rats
Mogensen, J., Svendsen, G., Tølbøll Lauritsen, K., Ermens, P., Hasman, A., Elvertorp, S., Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2003, In: Pharmacology, Biochemistry and Behavior. Vol. 76, p. 197-212Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Place learning and object recognition by rats subjected to transection of the fimbria-fornix and/or ablation of the prefrontal cortex
Mogensen, J., Lauritsen, K. T., Elvertorp, S., Hasman, A., Moustgaard, A. & Wörtwein, Gitta, 2004, In: Brain Research Bulletin. Vol. 63, no. 3, p. 217-36Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation
Sørensen, G., Lindberg, C., Wörtwein, Gitta, Bolwig, T. G., Woldbye, David Paul Drucker & Sørensen, G., 1 Sep 2004, In: Journal of Neuroscience Research. 77, 5, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats
Greisen, M. H., Altar, C. A., Bolwig, T. G., Whitehead, R. E. & Wörtwein, Gitta, 2005, In: Journal of Neuroscience Research. 79/6, p. 772-778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal separation affects male rat copulatory behaviour and hypothalamic corticotropin releasing factor in concert
Greisen, M. H., Bolwig, T. G., Husum, H., Nedergaard, P. & Wörtwein, Gitta, 2005, In: Behavioural Brain Research. 158(2), p. 367-375Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin tetrapeptide effects on HPA axis function and elevated plus maze behaviour in maternally separated and handled rats
Greisen, M. H., Bolwig, T. G. & Wörtwein, Gitta, 2005, In: Behavioural Brain Research. Vol 161, p. 204-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Egocentric spatial orientation in a water maze by rats subjected to transection of the fimbria-fornix and/or ablation of the prefrontal cortex
Mogensen, J., Moustgaard, A., Khan, U., Wörtwein, Gitta & Sandager Nielsen, K., 2005, In: Brain Research Bulletin. 65, 1, p. 41-58Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice
Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression?
Husum, H., Aznar, S., Hoyer-Hansen, S., Larsen, M. H., Mikkelsen, J. D., Moller, A., Mathe, A. A. & Wörtwein, Gitta, 2006, In: Journal of Neuroscience Research. 84, 6, p. 1292-1302 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of maternal separation on neuropetide Y and calcitonin gene-related peptide in "depressed" Flinders Sensitive Line rats: A study of gene-environment interactions
Wörtwein, Gitta, Husum, H., Andersson, W., Bolwig, T. G. & Mathe, A. A., 2006, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30, 4, p. 684-693 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test
Thomsen, M., Wörtwein, Gitta, Olesen, M. V., Begtrup, M., Havez, S., Bolwig, T. G. & Woldbye, David Paul Drucker, 2007, In: Brain Research. 1155, p. 49-55Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels
Christensen, R., Marcussen, A. B., Wörtwein, Gitta, Knudsen, G. M. & Aznar, S., 2008, In: Experimental Neurology. 210, 1, p. 164-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of maternal separation on adult mouse behaviour and on the total neuron number in the mouse hippocampus
Fabricius, K., Wörtwein, Gitta & Pakkenberg, B., 2008, In: Brain Structure and Function (Print Edition). 212, 5, p. 403-416 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electroconvulsive stimulations prevent stress-induced morphological changes in the hippocampus
Hageman, I., Nielsen, M., Wörtwein, Gitta, Diemer, N. H. & Jorgensen, M. B., 2008, In: Stress: The International Journal on the Biology of Stress . 11, 4, p. 282-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic electroconvulsive stimulation but not chronic restraint stress modulates mRNA expression of voltage-dependent potassium channels Kv7.2 and Kv11.1 in the rat piriform cortex.
Hjæresen, M., Hageman, Ida, Wörtwein, Gitta, Plenge, P., Jørgensen, Martin Balslev & Wörtwein, Gitta, 2008, In: Brain Research. 1217C, p. 179-184 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-environment interaction affects substance P and neurokinin A in the entorhinal cortex and periaqueductal grey in a genetic animal model of depression: implications for the pathophysiology of depression
Husum, H., Wörtwein, Gitta, Andersson, W., Bolwig, T. G. & Mathé, A. A., 2008, In: International Journal of Neuropsychopharmacology. 11, 1, p. 93-101 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Escitalopram reduces increased hippocampal cytogenesis in a genetic rat depression model
Petersén, A., Wörtwein, Gitta, Gruber, S. H. M. & Mathé, A. A., 2008, In: Neuroscience Letters. 436, 3, p. 305-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice
Sørensen, G., Sager, T. N., Petersen, Jørgen Holm, Brennum, L. T., Thøgersen, P., Hee Bengtsen, C., Thomsen, M., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2008, In: Psychopharmacology. 199, 1, p. 37-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats
Thomsen, M., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wörtwein, Gitta, Sager, T., Holm, R., Pepe, L. & Barak Caine, S., 2008, In: Psychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Electroconvulsive stimulations normalizes stress-induced changes in the glucocorticoid receptor and behaviour
Hageman, Ida, Nielsen, M., Wörtwein, Gitta, Diemer, N. H. & Jorgensen, M. B., 2009, In: Behavioural Brain Research. 196, 1, p. 71-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult Brain and Behavioral Effect of Early Life Maternal Deprivation
Mathe, A. A., El Khoury, A., Gruber, S. H. M., Husum, H., Wörtwein, Gitta & Arlinde, C., 2009, Beyond neuropsychiatric diagnostics: Symptoms not disorders. Palomo, T., Beninger, R. J., Kostzewa, R. M. & Archer, T. (eds.). Mountain Home, TN, USA: F. P. Graham Publishing Co.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Nortriptyline mediates behavioral effects without affecting hippocampal cytogenesis in a genetic rat depression model
Petersén, A., Wörtwein, Gitta, Gruber, S. H. M., El-Khoury, A. & Mathé, A. A., 2009, In: Neuroscience Letters. 451, 2, p. 148-51 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine
Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mekanismer ved funktionel restitution efter hjerneskader
Wörtwein, Gitta, 2009, Klinisk neuropsykologi. Gade, A., Gerlach, C., Starrfelt, R. & Møller Pedersen, P. (eds.). København: Frydenlund Academic, p. 480-488Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2010
- Published
Increased dopaminergic activity in socially isolated rats: an electrophysiological study
Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, Gitta, Steiniger-Brach, B., Sotty, F., Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, G., Steiniger-Brach, B. & Sotty, F., 27 Sep 2010, In: Neuroscience Letters. 482, 2, p. 117-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
Jeon, J., Dencker, D., Wörtwein, G., Woldbye, D. P. D., Cui, Y., Davis, A. A., Levey, A. I., Schütz, G., Sager, T. N., Mørk, A., Li, C., Deng, C-X., Fink-Jensen, A., Wess, J., Jeon, J., Nielsen, D. D., Wörtwein, G., Woldbye, D. P. D., Cui, Y., Davis, A. A. & 8 others, , 10 Feb 2010, In: Journal of Neuroscience. 30, 6, p. 2396-405 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice
Schmidt, L. S., Miller, A. D., Lester, D. B., Bay-Richter, C., Schülein, C., Frikke-Schmidt, H., Wess, J., Blaha, C. D., Woldbye, David Paul Drucker, Fink-Jensen, Anders & Wörtwein, Gitta, 2010, In: Psychopharmacology. 207, 4, p. 547-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice
Christiansen, S. H. O., Olesen, M. V., Wörtwein, Gitta & Woldbye, David Paul Drucker, 20 Jan 2011, In: Behavioural Brain Research. 216, 2, p. 585-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline
Dencker, D., Wörtwein, Gitta, Weikop, Pia, Jeon, J., Thomsen, M., Sager, T. N., Mørk, A., Woldbye, David Paul Drucker, Wess, J. & Fink-Jensen, Anders, 2011, In: Journal of Neuroscience. 31, 16, p. 5905-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease
Dencker, D., Thomsen, M., Wörtwein, Gitta, Weikop, Pia, Cui, Y., Jeon, J., Wess, J. & Fink-Jensen, Anders, 22 Nov 2011, In: ACS Chemical Neuroscience. 3, 2, p. 80-89 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological characterization of social isolation-induced hyperactivity
Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, Gitta & Steiniger-Brach, B., 2011, In: Psychopharmacology. 215, 2, p. 257-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Socially isolated rats exhibit changes in dopamine homeostasis pertinent to schizophrenia
Fabricius, K., Steiniger-Brach, B., Helboe, L., Fink-Jensen, Anders & Wörtwein, Gitta, 2011, In: International Journal of Developmental Neuroscience. 29, 3, p. 347-50 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.
Fink-Jensen, Anders, Schmidt, L. S., Dencker, D., Schülein, C., Wess, J., Wörtwein, Gitta & Woldbye, David Paul Drucker, 10 Apr 2011, In: European Journal of Pharmacology. 656, 1-3, p. 39-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12474
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Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
Research output: Contribution to journal › Journal article › Research › peer-review
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PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis
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Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels
Research output: Contribution to journal › Journal article › Research › peer-review
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