Steffen Loft
Professor
Section of Environmental Health
Øster Farimagsgade 5, 1014 København K, 15 Øster Farimagsgade 5, Building: 15-1-07
Member of:
- 1990
- Published
Cytochrome P450 IA2 activity in man measured by caffeine metabolism: Effect of smoking, broccoli and exercise
Vistisen, K., Poulsen, Henrik Enghusen & Loft, Steffen, 1990, Biological Ractive Intermediates IV. New York: Plenum Publishing Corporation, p. 407-11Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Pharmacokinetics and Pharmadynamics of oxazepam metabolism of paracetamol in severe hypothyroidism
Sonne, J., Boesgaard, S., Poulsen, Henrik Enghusen, Loft, Steffen, Hansen, J. M., Døssing, M. & Andreasen, F., 1990, In: British Journal of Clinical Pharmacology. 30, p. 737-42Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Acute ethanol administration reduces the antidote effect of N-acetylcysteine after acetaminophen overdose in mice.
Dalhoff, K., Hansen, P. B., Ott, P., Loft, Steffen & Poulsen, Henrik Enghusen, 1991, In: Human & Experimental Toxicology. 10, p. 431-433Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of metronidazole by human liver microsomes
Loft, Steffen, Otton, S. V., Lennard, M. L., Tucker, G. T. & Poulsen, Henrik Enghusen, 1991, In: Biochemical Pharmacology. 41, p. 1127-34Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic responses to intermittent hepatic dearterialization in the rat
Sjövall, S., Ahrén, B., Hansson, P., Loft, Steffen, Poulsen, Henrik Enghusen & Bengmark, S., 1991, In: Journal of Hepatology. 13, p. 33-7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metronidazole and antipyrine metabolism in the rat: Clearance determination from one saliva sample
Loft, Steffen, Nielsen, A. J., Borg, B. E. & Poulsen, Henrik Enghusen, 1991, In: Xenobiotica. 21, p. 33-46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single dose pharmacokinetics and pharmadynamics of oral oxazepam in very elderly institutionalised subjects
Sonne, J., Loft, Steffen, Døssing, M., Boesgaard, S. & Andreasen, F., 1991, In: British Journal of Clinical Pharmacology. 31, p. 719-22Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
8-hydroxydeoxyguanosine in vitro: effects of glutathione, ascorbate and 5-aminosalicylic acid
Fischer-Nielsen, A., Poulsen, Henrik Enghusen & Loft, Steffen, 1992, In: Free Radical Biology & Medicine. 13, p. 121-126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disulfiram therapy - adverse reactions and interactions
Poulsen, Henrik Enghusen, Loft, Steffen & Andersen, M., 1992, In: Acta Psychiatrica Scandinavica. 86 suppl.369, p. 59-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disulfiram therapy – adverse drug reactions and interactions
Poulsen, Henrik Enghusen, Loft, Steffen, Andersen, Jens Rikardt & Andersen, Morten, 1992, In: Acta Psychiatrica Scandinavica. 86, 369 S, p. 59-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine
Vistisen, K., Poulsen, Henrik Enghusen & Loft, Steffen, 1992, In: Carcinogenesis. 13, p. 1561-1568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of indolyl glucosinolates (±myrosinases) on the in vivo metabolism of metronidazole and antipyrine in the rat
Loft, Steffen, Otte, J., Poulsen, Henrik Enghusen & Sørensen, H., 1992, In: Food and Chemical Toxicology. 30, p. 927-935Research output: Contribution to journal › Journal article › Research
- Published
Interaction of smoking, PAH uptake and cytochrome P450 activity among foundry workers
Sherson, D., Sigsgaard, T., Overgaard, E., Loft, Steffen, Poulsen, Henrik Enghusen & Jongeneelen, F., 1992, In: British Journal of Industrial Medicine. 49, p. 197-202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of smoking, uptake of polycyclic aromatic hydrocarbons, and cytochrome P450IA2 activity among foundry workers
Sherson, D., Sigsgaard, T., Overgaard, E., Loft, Steffen, Poulsen, H. E. & Jongeneelen, F. J., 1992, In: British Journal of Industrial Medicine. 49, 3, p. 197-202 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Miljø- og arbejdsmedicin
Hansen, E. S. & Loft, Steffen, 1992, København: FADL's Forlag. 298 p.Research output: Book/Report › Book › Research
- Published
Oxidative DNA damage estimated by 8-hydroxydeoxy guanosine excretion in humans: influence of smoking gender and body mass index
Loft, Steffen, Vistisen, K. K., Ewertz, M., Tjønneland, A., Overvad, K. & Poulsen, Henrik Enghusen, 1992, In: Carcinogenesis. 13, p. 2241-2247Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
8-Hydroxydeoxyguanosine as a urinary biomarker of Oxidative DNA-damage
Loft, Steffen, Fischer-Nielsen, A., Jeding, I. B., Vistisen, K. & Poulsen, Henrik Enghusen, 1993, In: Journal of Toxicology and Environmental Health. Part A. 40, p. 397-410Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of nitroglycerin depend on both plasma and intracellular sulfhydryl compound levels in vivo. Effect of agents with different sulfhydryl-modulating properties
Boesgaard, S., Poulsen, H. E., Aldershvile, J., Loft, Steffen, Anderson, M. E. & Meister, A., 1993, In: Circulation. 87, 2, p. 547-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of nitroglycerine depend on both plasma and intracellular sulfhydryl compound levels in vivo. Effect of agents with different sulfhydryl modulating properties
Boesgaard, S., Poulsen, Henrik Enghusen, Aldershvile, J., Loft, Steffen, Anderson, M. E. & Meister, A., 1993, In: Circulation. 87, p. 547-553Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer risk related to genetic polymorphisms in carcinogen metabolism and DNA repair
Poulsen, Henrik Enghusen, Loft, Steffen & Wasserman, K., 1993, In: Basic & Clinical Pharmacology & Toxicology. 72, suppl. 1, p. 93-103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis
Ranek, L., Dalhoff, K., Poulsen, Henrik Enghusen, Brøsen, K., Flachs, H., Loft, Steffen & Wantzin, P., 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 677-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of ascorbate and 5-aminosalicylic acid on light-induced 8-hydroxydeoxyguanosine formation in V79 Chinese hamster cells
Fischer-Nielsen, A., Loft, Steffen & Jensen, K. G., 1993, In: Carcinogenesis. 14, no. 11, p. 2431-2433Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Benzo[a]pyrene and (±)-trans-7, 8-dihydroxy-7, 8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2
Jensen, K. G., Önfelt, A., Poulsen, Henrik Enghusen, Döhmer, J. & Loft, Steffen, 1993, In: Carcinogenesis. 14, p. 2115-2118Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluvoxamine is a potent inhibitor of cytochrome P4501A2
Brøsen, K., Skjelbo, E., Rasmussen, B. B., Poulsen, Henrik Enghusen & Loft, Steffen, 1993, In: Biochemical Pharmacology. 45, p. 1211-1214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lungecancerrisici blandt støberiarbejdere
Sherson, D., Sigsgaard, T. I., Overgaard, E., Loft, Steffen, Poulsen, Henrik Enghusen & Jongeneelen, F. C., 1993, In: Ugeskrift for læger. 155, p. 620-623Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolism of phenacetin in V79 Chinese hamster cell cultures expressing rat liver CYP1A2 compared to isolated rat hepatocytes
Jensen, K. G., Loft, Steffen, Döhmer, J. & Poulsen, Henrik Enghusen, 1993, In: Biochemical Pharmacology. 45, p. 1171-1173Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No induction of extrahepatic antipyrine and metronidazole metabolism evaluated from partially hepatectomized rats
Jeding, E., Loft, Steffen & Poulsen, Henrik Enghusen, 1993, In: Xenobiotica. 23, p. 411-418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of biliary decompression on bacterial translocation in jaundiced rats
Ding, J. W., Andersson, R., Soltesz, V., Willén, R., Loft, Steffen, Poulsen, Henrik Enghusen, Pärsson, H., Olsson, K. & Bengmark, S., 1993, In: Journal of Hepato - Biliary - Pancreatic Surgery. 7, p. 99-110Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
In vivo-induced nitrate tolerance is not associated with depletion of arterial or venous thiol levels
Boesgaard, S., Aldershvile, J., Poulsen, Henrik Enghusen, Loft, Steffen, Anderson, M. E. & Meister, A., 1994, In: Circulation Research. 74, p. 115-120Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidativ DNA damage correlates with oxygen consumption in man
Loft, Steffen, Astrup, A., Buemann, B. & Poulsen, Henrik Enghusen, 1994, In: The FASEB Journal. 8, p. 534-537Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative DNA damage correlates with oxygen consumption in humans
Loft, Steffen, Astrup, A., Buemann, B. & Poulsen, Henrik Enghusen, 1994, In: FASEB Journal. 8, 8, p. 534-537 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiation induced formation of 8-hydroxy-2'-deoxyguanosine and its prevention by scavangers
Fischer-Nielsen, A., Jeding, I. B. & Loft, Steffen, 1994, In: Carcinogenesis. 15, p. 121-126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous determination of urinary free cortisol and 6*Gb-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, p. 23-29Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Oxidant and Antioxidant Functions of Estrogens
Poulsen, Henrik Enghusen, Lykkesfeldt, J. & Loft, Steffen, 1994, HRT's Impact of Menopausal Changes. Proceedings of the Novo Nordisk International Symposium, Copenhagen, Denmark, May 6th-7th, 1994. Danmark, p. 91-102Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
The impact of genetic polymorphisms in risk assessment of drugs
Poulsen, Henrik Enghusen & Loft, Steffen, 1994, In: Archives of Toxicology. Suppl. 16, p. 211-222Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 3 Oct 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, 1, p. 23-29 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Cytochrome P4502E1 Inhibition by Propylene Glycol prevents Acetaminophen (Paracetamol) Hepatotoxicity in mice without Cytochrome P4501A2 Inhibition
Thomsen, M. S., Loft, Steffen, Roberts, D. W. & Poulsen, Henrik Enghusen, 1995, In: Basic & Clinical Pharmacology & Toxicology. 76, p. 395-399Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1995, In: Analytical Biochemistry. 229, p. 329-335Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early bichemical markers of effects: Enzyme induction, oncogene activation and markers of oxidative damage
Poulsen, Henrik Enghusen & Loft, Steffen, 1995, In: Toxicology. 101, p. 55-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Energy restriction and oxidative DNA damage in humans
Loft, Steffen, Velthuis-te Wierik, E. J. M., van der Berg, H. & Poulsen, Henrik Enghusen, 1995, In: Cancer Epidemiology, Biomarkers & Prevention. 4, p. 515-519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics and inhibition by fluvoxamine of phenacetin O-deethylation in V79 cells expressing CYP1A2
Jensen, K. G., Poulsen, Henrik Enghusen, Döhmer, J. & Loft, Steffen, 1995, In: Basic & Clinical Pharmacology & Toxicology. 76, p. 286-288Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Menadione-induced DNA fragmentation without 8-hydroxy-2'-deoxyguanosine formation in isolated rat hepatocytes
Fischer-Nielsen, A., Corcoran, G. B., Poulsen, Henrik Enghusen, Kamandulis, L. & Loft, Steffen, 1995, In: Biochemical Pharmacology. 49, p. 1469-1474Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No influence of beta-carotene on oxidative DNA damage in male smokers
van Poppel. G., Poulsen, Henrik Enghusen, Loft, Steffen & Verhagen, H., 1995, In: JNCI - Journal of the National Cancer Institute. 87, p. 310-311Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative DNA damage after transplantation of the liver and small intestine in pigs
Loft, Steffen, Larsen, P. N., Rasmussen, A., Fischer-Nielsen, A., Bondesen, S., Kirkegaard, P., Rasmussen, L. S., Ejlersen, E., Tornøe, K., Bergholdt, R. & Poulsen, Henrik Enghusen, 1995, In: Transplantation. 59, p. 16-20Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of oxidative DNA in man by Brussels sprouts
Verhagen, H., Poulsen, Henrik Enghusen, Loft, Steffen, van Poppel, G., Willems, M. I. & van Bladeren, P. J., 1995, In: Carcinogenesis. 16, p. 969-970Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restricted pulmonary diffusion capacity after exercise is not an ARDS-like injury
Nielsen, H. B., Hanel, B., Loft, Steffen, Poulsen, Henrik Enghusen, Pedersen, B. K., Diamant, M., Vistisen, K. K. & Secher, N. H., 1995, In: Journal of Sports Sciences. 13, p. 109-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine
Rasmussen, B. B., Mäenpää, J., Pelkonen, O., Loft, Steffen, Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Brøsen, K., 1995, In: British Journal of Clinical Pharmacology. 39, p. 151-159Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term moderate energy restriction does not affect indicators of oxidative stress and genotoxicity in humans
Velthuis-te Wierik, E. J. M., van Leeuwen, R. E., Hendriks, H. F., Verhagen, H., Loft, Steffen, Poulsen, Henrik Enghusen & Van den Berg, H., 1995, In: Journal of Nutrition. 125, p. 2631-2639Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine
Jeppesen, U., Gram, L. F., Vistisen, K., Loft, Steffen, Poulsen, Henrik Enghusen & Brøsen, K., 1996, In: European Journal of Clinical Pharmacology. 51, 1, p. 73-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex vivo time-dependent cell DNA-degradation shown by single cell gel electrophoresis
Tuo, J., Loft, Steffen, Thomsen, M. S. & Poulsen, Henrik Enghusen, Jan 1996, In: Pharmacology & Toxicology. 78, 1, p. 55-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11086
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Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults
Research output: Contribution to journal › Journal article › Research › peer-review
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504
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Assessment of impact of traffic-related air pollution on morbidity and mortality in Copenhagen Municipality and the health gain of reduced exposure
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Long-term exposure to low levels of air pollution and mortality adjusting for road traffic noise: A Danish Nurse Cohort study
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