Evaluation of simple tests for detection of HIV antibodies: analysis of interobserver variation in Tanzania
Research output: Contribution to journal › Journal article › Research › peer-review
200 sera were tested for HIV antibodies with different tests in Tanzania. The results were interpreted by 5 different observers with different laboratory experience. There was considerable variation between observers and between testing methods. HIV-Chek was easiest to perform with little interobserver variation, but a few probably false negative readings were seen. Serodia gave many false positives. Western Blots gave more diverging results due to indeterminate sera and lack of training. HIV-Chek seems best when time, facilities, and training are limited and if combined with Serodia false negative results can be excluded.
| Original language | English |
|---|---|
| Journal | Scandinavian Journal of Infectious Diseases |
| Volume | 22 |
| Issue number | 3 |
| Pages (from-to) | 283-5 |
| Number of pages | 3 |
| ISSN | 0036-5548 |
| Publication status | Published - 1 Jan 1990 |
- Blotting, Western, Enzyme-Linked Immunosorbent Assay, False Negative Reactions, False Positive Reactions, HIV Antibodies, HIV Infections, Humans, Observer Variation, Predictive Value of Tests, Tanzania
Research areas
ID: 33890974