Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients

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Standard

Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients. / Skinhøj, P; Hofmann, B; Jacobsen, K D; Lerche, B; Frederiksen, B; Bygbjerg, Ib Christian; Petersen, C S; Dickmeiss, E; Svejgaard, A.

In: Scandinavian Journal of Infectious Diseases, Vol. 21, No. 2, 01.01.1989, p. 149-53.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Skinhøj, P, Hofmann, B, Jacobsen, KD, Lerche, B, Frederiksen, B, Bygbjerg, IC, Petersen, CS, Dickmeiss, E & Svejgaard, A 1989, 'Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients', Scandinavian Journal of Infectious Diseases, vol. 21, no. 2, pp. 149-53.

APA

Skinhøj, P., Hofmann, B., Jacobsen, K. D., Lerche, B., Frederiksen, B., Bygbjerg, I. C., Petersen, C. S., Dickmeiss, E., & Svejgaard, A. (1989). Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients. Scandinavian Journal of Infectious Diseases, 21(2), 149-53.

Vancouver

Skinhøj P, Hofmann B, Jacobsen KD, Lerche B, Frederiksen B, Bygbjerg IC et al. Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients. Scandinavian Journal of Infectious Diseases. 1989 Jan 1;21(2):149-53.

Author

Skinhøj, P ; Hofmann, B ; Jacobsen, K D ; Lerche, B ; Frederiksen, B ; Bygbjerg, Ib Christian ; Petersen, C S ; Dickmeiss, E ; Svejgaard, A. / Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients. In: Scandinavian Journal of Infectious Diseases. 1989 ; Vol. 21, No. 2. pp. 149-53.

Bibtex

@article{d7da8dd1b3c74241ba477c34e70165b3,
title = "Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients",
abstract = "HIV antigenemia was found in 52/243 HIV antibody positive individuals attending 2 AIDS-screening clinics, giving a prevalence of 13, 25 and 76% in CDC groups II, III and IV, respectively. No correlation was found to decreased CD4 lymphocyte values in the individual groups. HIV antigen therefore identified a separate subpopulation. For 138 asymptomatic patients followed prospectively both laboratory parameters predicted HIV-related events, the relative risk factor being 4 for low CD4 value and 6 for presence of HIV antigen. Individuals presenting with HIV antigen and decreased CD4 count all developed disease within 18 months, the relative risk factor being 24. Thus the 2 markers, when measured together, effectively separated asymptomatic HIV-infected patients into 1 of 3 risk categories.",
keywords = "Antigens, Differentiation, T-Lymphocyte, HIV Antibodies, HIV Antigens, HIV Seropositivity, Humans, Leukocyte Count, Lymphocytes, Predictive Value of Tests, Prognosis, Risk Factors",
author = "P Skinh{\o}j and B Hofmann and Jacobsen, {K D} and B Lerche and B Frederiksen and Bygbjerg, {Ib Christian} and Petersen, {C S} and E Dickmeiss and A Svejgaard",
year = "1989",
month = jan,
day = "1",
language = "English",
volume = "21",
pages = "149--53",
journal = "Infectious Diseases",
issn = "2374-4235",
publisher = "Taylor & Francis",
number = "2",

}

RIS

TY - JOUR

T1 - Independent clinical significance of HIV antigen determination and CD4 counts in anti-HIV positive patients

AU - Skinhøj, P

AU - Hofmann, B

AU - Jacobsen, K D

AU - Lerche, B

AU - Frederiksen, B

AU - Bygbjerg, Ib Christian

AU - Petersen, C S

AU - Dickmeiss, E

AU - Svejgaard, A

PY - 1989/1/1

Y1 - 1989/1/1

N2 - HIV antigenemia was found in 52/243 HIV antibody positive individuals attending 2 AIDS-screening clinics, giving a prevalence of 13, 25 and 76% in CDC groups II, III and IV, respectively. No correlation was found to decreased CD4 lymphocyte values in the individual groups. HIV antigen therefore identified a separate subpopulation. For 138 asymptomatic patients followed prospectively both laboratory parameters predicted HIV-related events, the relative risk factor being 4 for low CD4 value and 6 for presence of HIV antigen. Individuals presenting with HIV antigen and decreased CD4 count all developed disease within 18 months, the relative risk factor being 24. Thus the 2 markers, when measured together, effectively separated asymptomatic HIV-infected patients into 1 of 3 risk categories.

AB - HIV antigenemia was found in 52/243 HIV antibody positive individuals attending 2 AIDS-screening clinics, giving a prevalence of 13, 25 and 76% in CDC groups II, III and IV, respectively. No correlation was found to decreased CD4 lymphocyte values in the individual groups. HIV antigen therefore identified a separate subpopulation. For 138 asymptomatic patients followed prospectively both laboratory parameters predicted HIV-related events, the relative risk factor being 4 for low CD4 value and 6 for presence of HIV antigen. Individuals presenting with HIV antigen and decreased CD4 count all developed disease within 18 months, the relative risk factor being 24. Thus the 2 markers, when measured together, effectively separated asymptomatic HIV-infected patients into 1 of 3 risk categories.

KW - Antigens, Differentiation, T-Lymphocyte

KW - HIV Antibodies

KW - HIV Antigens

KW - HIV Seropositivity

KW - Humans

KW - Leukocyte Count

KW - Lymphocytes

KW - Predictive Value of Tests

KW - Prognosis

KW - Risk Factors

M3 - Journal article

C2 - 2786246

VL - 21

SP - 149

EP - 153

JO - Infectious Diseases

JF - Infectious Diseases

SN - 2374-4235

IS - 2

ER -

ID: 33891257